研究成果 (75)

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Adaptation of host transmission cycle during Clostridium difficile speciation
Kumar N, Browne HP, Viciani E, Forster SC, Clare S, Harcourt K, Stares MD, Dougan G, Fairley DJ, Roberts P, Pirmohamed M, Clokie MRJ, Jensen MBF, Hargreaves KR, Ip M, Wieler LH, Seyboldt C, Norén T, Riley TV, Kuijper EJ, Wren BW, Lawley TD ( 2019 )
Nature genetics
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1038/s41588-019-0478-8
An Interim Analysis on the First Hong Kong Chinese Newborn Microbiome Cohort - Smart Baby (Stool Microbiome & Allergic Reaction Study)
Paul KS Chan, TF Leung, WH Tam, YK Yeoh, Apple CM Yeung, Jenifer WK Yau ( 2019 )
Refereed conference paper presented and published in conference proceedings
Antibiotic-Resistant Community-Acquired Bacterial Pneumonia
Ho J., Ip M. ( 2019 )
Infectious Disease Clinics of North America
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.idc.2019.07.002
A randomized controlled trial evaluating efficacy of promoting human papillomavirus (HPV) vaccination among Chinese men who have sex with men
Wang Z, Lau JT, Ip M, Lam PKP, Fong F, Chan P ( 2019 )
Refereed conference paper presented and published in conference proceedings
Are reusable blood collection tube holders the culprit for nosocomial hepatitis C virus transmission?
Tsang DNC, Ip M, Chan PKS, Ching PTY, Lam HS, Seto WH ( 2019 )
Infection Control and Hospital Epidemiology
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1017/ice.2018.302
A Small RNA Transforms the Multidrug Resistance of Pseudomonas aeruginosa to Drug Susceptibility
Law COK, Huang C, Pan Q, Lee J, Hao Q, Chan TF, Lo NWS, Ang IL, Koon A, Ip M, Chan E, Lau TCK ( 2019 )
Molecular Therapy - Nucleic Acids
Publication in refereed journal
典藏於此文庫的全文:
95486376.pdf
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.omtn.2019.02.011
Bioﬁlm production among bloodstream isolates of Candida albicans, C. tropicalis and C. parapsilosis
Y Poon, M Hui ( 2019 )
Other conference paper
Clinical Implications of Unmasking Dormant Conduction After Circumferential Pulmonary Vein Isolation in Atrial Fibrillation Using Adenosine: A Systematic Review and Meta-Analysis
Chen C, Li DB, Ho J, Liu T, Li XT, Wang Z, Lin YJ, Zou FQ, Tse G, Xia YL ( 2019 )
Frontiers in Physiology
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.3389/fphys.2018.01861
Comparison of high-flow nasal cannula versus oxygen face mask for environmental bacterial contamination in critically ill pneumonia patients: a randomized controlled crossover trial
Leung, Joynt, Gomersall, Wong, Lee, Ling, Chan, Lui, Tsoi, Ling, Hui ( 2019 )
The Journal of hospital infection
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.jhin.2018.10.007
Design, synthesis and biological evaluation of antimicrobial diarylimine and -amine compounds targeting the interaction between the bacterial NusB and NusE proteins
Yangyi Qiu, Shu Ting Chan, Lin Lin, Tsun Lam Shek, Tsz Fung Tsang, Nilakshi Barua, Yufeng Zhang, Margaret Ip, Paul Kay-sheung Chan, Nicolas Blanchard, Gilles Hanquet, Zhong Zuo, Xiao Yang, Cong Ma ( 2019 )
European journal of medicinal chemistry
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.ejmech.2019.05.090
Detection of Human Pegivirus in Blood of Immunocompromised Children with Acute Myeloid Leukemia
Martin Chi-Wai Chan, Kirran N. Mohammad, Lin-Yao Zhang, Wai-Ling Lam, Frankie W.T. Cheng, Paul K.S. Chan ( 2019 )
Refereed conference paper presented and published in conference proceedings
Donor Fungi and Bacteria Engraftment After Successful Eradication of Carbapenem-Resistant Enterobacteriaceae with Fecal Microbiota Transplantation: Serial Fecal Metagenomics Analysis
Liu Q, Yang K, XU Z, Zuo T, Tang W, Zhang F, Lau LHS, Lui RN, Wong R, Chin ML, Chan PK, Chan FK, Lui GC, Ng SC ( 2019 )
Gastroenterology
Refereed conference paper presented and published in conference proceedings
數位物件識別號 (DOI): http://dx.doi.org/10.1016/S0016-5085(19)37116-1
Early-life Emollient Use and Skin Hydration are Predictive Factors for Infantile Eczema in Chinese Babies
Ting Fan Leung, Shuk Man Li, Ye-Hao Chen, Jennifer Wing Ki Yau, Agnes Sze Yin Leung, Kate Ching Ching Chan, Cecily Woon Wa Leung, Nam Sze Cheng, Mei Kam Chang, Paul Kay Sheung Chan, Wing Hung Tam ( 2019 )
Refereed conference paper presented and published in conference proceedings
Economic Analysis of Herpes Zoster in a Hospital Setting in Hong Kong
Wai-kit Ming, Wing-yin Yu, Owen Tak-yin Tsang, Paul Kay-sheung Chan, Joyce Hoi-sze You ( 2019 )
Acta dermato-venereologica
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.2340/00015555-3118
Effectiveness of antimicrobial hospital curtains on reducing bacterial contamination—A multicenter study
Luk S, Chow VCY, Yu KCH, Hsu EK, Tsang NC, Chuang VWM, Lai CKC, Hui M, Lee RA, Lai WM, Que TL, Fung SC, To WK, Cheng VCC, Wong ATY ( 2019 )
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1017/ice.2018.315.
Establishment of three human intestinal enteroid lines to study human norovirus infection
Jenny C.M. Chan, Kirran N. Mohammad, Sunny Hei Wong, Martin Chi-Wai Chan ( 2019 )
Refereed conference paper presented and published in conference proceedings
Evaluation of Oral Cavity DNA Extraction Methods on Bacterial and Fungal Microbiota
Rosenbaum, Usyk, Chen, Zolnik, Jones, Waldron, Dowd, Thorpe, Burk ( 2019 )
Scientific reports
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1038/s41598-018-38049-6
Evaluation of potential herb-drug interactions between oseltamivir and commonly used anti-influenza Chinese medicinal herbs
Yufeng Zhang, Chunming Lyu, Sophia Yui Kau Fong, Qian Wang, Chenrui Li, Nicolas James Ho, Kay Sheung Chan, Xiaoyu Yan, Zhong Zuo ( 2019 )
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.jep.2019.112097
Evolution and global transmission of a multidrug-resistant, community-associated methicillin-resistant staphylococcus aureus lineage from the Indian subcontinent
Eike J. Steinig, Sebastian Duchene, D. Ashley Robinson, Stefan Monecke, Maho Yokoyama, Maisem Laabei, Peter Slickers, Patiyan Andersson, Deborah Williamson, Angela Kearns, Richard V. Goering, Elizabeth Dickson, Ralf Ehricht, Margaret Ip, Matthew V. N. O’Sullivan, Geoffrey W. Coombs, Andreas Petersen, Grainne Brennan, Anna C. Shore, David C. Coleman, Annalisa Pantosti, Herminia de Lencastre, Henrik Westh, Nobumichi Kobayashi, Helen Heffernan, Birgit Strommenger, Franziska Layer, Stefan Weber, Hege Vangstein Aamot, Leila Skakni, Sharon J. Peacock, Derek Sarovich, Simon Harris, Julian Parkhill, Ruth C. Massey, Mathew T. G. Holden, Stephen D. Bentley, Steven Y. C. Tong ( 2019 )
mBio
Publication in refereed journal
典藏於此文庫的全文:
143798099.pdf
數位物件識別號 (DOI): http://dx.doi.org/10.1128/mBio.01105-19
Faecal microbiota transplantation for treatment of recurrent or refractory Clostridioides difficile infection in Hong Kong
Lui, Wong, Lau, Chan, Cheung, Li, Chin, Tang, Ching, Lam, Chan, Wu, Sung, Chan, Ng ( 2019 )
Hong Kong medical journal = Xianggang yi xue za zhi
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.12809/hkmj197855
Fecal microbiota transplantations reconstitute gut fungal and viral microbiota in graft-versus-host disease
Zhang F, Yeoh YK, Zuo T, Cheng F, Tang W, Cheung K, Yang K, Liu Q, Cheung CP, Mo CC, Hui M, Chan F, Li C, Chan P ( 2019 )
Gut; Gut
Refereed conference paper presented and published in conference proceedings
數位物件識別號 (DOI): http://dx.doi.org/10.1136/gutjnl-2019-IDDFAbstracts.172
First-In-Class Inhibitors Targeting the Interaction between Bacterial RNA Polymerase and Sigma Initiation Factor Affect the Viability and Toxin Release of Streptococcus pneumoniae
J Ye, AJ Chu, L Lin, X Yang, C Ma ( 2019 )
Molecules
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.3390/molecules24162902
Genetic Susceptibility of Hong Kong Ethnic Chinese to Severe Influenza and RSV Infections
Chan Martin Chi Wai, Lee Nelson, Ma Ronald Ching Wan, Graham Colin A, Chan Paul Kay Sheung ( 2019 )
Refereed conference paper presented and published in conference proceedings
Genetic susceptibility to Tuberculosis: Interaction between HLA-DQA1 and age of onset
Tang NLS, Wang XY, Chang KC, Chan CY, Szeto NWS, Huang D, Wu JY, Lui GCY, Leung CC, Hui M ( 2019 )
INFECTION GENETICS AND EVOLUTION
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.meegid.2018.12.014
Global Pediatric Norovirus Surveillance Network (NoroSurv)
Vinje J, Selvarangan R, Pietsch C, Bonifacio J, Pang X, Rahman M, Giri S, Sakon N, Chan M ( 2019 )
Refereed conference paper presented and published in conference proceedings
Gut mucosal virome alterations in ulcerative colitis
Zuo T, Lu XJ, Zhang Y, Cheung CP, Lam S, Zhang F, Tang W, Ching JYL, Zhao R, Chan PKS, Sung JJY, Yu J, Chan FKL, Cao Q, Sheng JQ, Ng SC ( 2019 )
Gut
Publication in refereed journal
典藏於此文庫的全文:
Gut mucosal virome alterations in ulcerative colitis.pdf
數位物件識別號 (DOI): http://dx.doi.org/10.1136/gutjnl-2018-318131
Higher viral load of emerging norovirus GII.P16-GII.2 than pandemic GII.4 and epidemic GII.17, Hong Kong, China
Sarah K.C. Cheung, Kirsty Kwok, Lin-Yao Zhang, Kirran N. Mohammad, Grace C.Y. Lui, Nelson Lee, E. Anthony S. Nelson, Raymond W.M. Lai, Ting F. Leung, Paul K.S. Chan, Martin Chi-Wai Chan ( 2019 )
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.3201/eid2501.180395
Human organoids: past, present, and future
Martin Chi-Wai Chan, Jenny C.M. Chan ( 2019 )
Chapter in an edited book (author)
Human papillomavirus 16 sub-lineage dispersal and cervical cancer risk worldwide: Whole viral genome sequences from 7116 HPV16-positive women
Clifford G., Tenet V., Georges D., Alemany L., Pavón M., Chen Z., Yeager M., Cullen M., Boland J., Bass S., Steinberg M., Raine-Bennett T., Lorey T., Wentzensen N., Walker J., Zuna R., Schiffman M., Mirabello L. ( 2019 )
Papillomavirus Research
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.pvr.2019.02.001
Human papillomavirus E6 oncoprotein interacts with Aurora kinase B
Siaw Shi Boon, KYC Lee, PKS Chan ( 2019 )
Refereed conference paper presented and published in conference proceedings
Human papillomavirus type 18 oncoproteins exert their oncogenicity in esophageal and tongue squamous cell carcinoma cell lines distinctly
Siaw Shi Boon, Zigui Chen, Jintao Li, Karen Y. C. Lee, Liuyang Cai, Rugang Zhong, Paul K. S. Chan ( 2019 )
BMC Cancer
Publication in refereed journal
典藏於此文庫的全文:
s12885-019-6413-7.pdf
數位物件識別號 (DOI): http://dx.doi.org/10.1186/s12885-019-6413-7
Impact of inter- and intra-individual variation, sample storage and sampling fraction on human stool microbial community profiles
Yeoh YK, Chen ZG, Hui MM, Wong MCS, Ho WCS, Chin ML, Ng SC, Chan FKL, Chan PKS ( 2019 )
PEERJ
Publication in refereed journal
典藏於此文庫的全文:
peerj-6172.pdf
數位物件識別號 (DOI): http://dx.doi.org/10.7717/peerj.6172
Impact of Preservation Method and 16S rRNA Hypervariable Region on Gut Microbiota Profiling
Zigui Chen, Pak Chun Hui, Mamie Hui, Yun Kit Yeoh, Po Yee Wong, Martin C. W. Chan, Martin C. S. Wong, Siew C. Ng, Francis K. L. Chan, Paul K. S. Chan ( 2019 )
mSystems
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1128/mSystems.00271-18
Increased Bacteriophage Abundance and Loss of Viralbacterial Interactions in the Mucosa of Ulcerative Colitis: Key to Pathogenesis?
Zuo T, Lu X, Cheung CP, Lam S, Zhang F, Tang W, Ching JY, Zhao R, Chan PK, Sung JJ, Yu J, Chan FK, Sheng J, Ng SC ( 2019 )
Gastroenterology
Refereed conference paper presented and published in conference proceedings
數位物件識別號 (DOI): http://dx.doi.org/10.1016/S0016-5085(19)36903-3
Initial experience of faecal microbiota transplantation with frozen stools for the treatment of recurrent or refractory clostridioides difficile infection – a retrospective review from a quaternary referral centre in Hong Kong
Lui R, Lau L, Chan T, Wong S, Cheung K, Li A, Chin M, Tang W, Ching J, Lam K, Chan P, Wu J, Sung J, Chan F, CNG S ( 2019 )
Gut; Gut
Refereed conference paper presented and published in conference proceedings
數位物件識別號 (DOI): http://dx.doi.org/10.1136/gutjnl-2019-IDDFAbstracts.189
In vitro inhibition on biofilm production of Candida species by probiotic Lactobacillus strains
Y Poon, M Hui ( 2019 )
Other conference paper
Liquid biopsy of HPV DNA in cervical cancer
Tak Hong Cheung, So Fan Yim, Mei Yun Yu, Michael J. Worley, Stephen J. Fiascone, Rossa W.K. Chiu, Keith W.K. Lo, Nelson S.S. Siu, Martin C.S. Wong, Apple C.M. Yeung, Raymond R.Y. Wong, Zi Gui Chen, Kevin M. Elias, Tony K.H. Chung, Ross S. Berkowitz, Yick Fu Wong, Paul K.S. Chan ( 2019 )
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.jcv.2019.03.005
Metagenomic identification and winter seasonality of picobirnavirus in stool of hospitalized patients with acute gastroenteritis
Martin Chi-Wai Chan, Lin-Yao Zhang, Liutao Guo, Paul K.S. Chan ( 2019 )
Refereed conference paper presented and published in conference proceedings
Molecular detection of respiratory pathogens and typing of human rhinovirus of adults hospitalized for exacerbation of asthma and chronic obstructive pulmonary disease
Fanny Wai-san Ko, Paul Kay-sheung Chan, Renee W. Y. Chan, Ka-Pang Chan, April Ip, Angela Kwok, Jenny Chun-li Ngai, So-Shan Ng, Chan Tat On, David Shu-cheong Hui ( 2019 )
RESPIRATORY RESEARCH
Publication in refereed journal
典藏於此文庫的全文:
141776791.pdf
數位物件識別號 (DOI): http://dx.doi.org/10.1186/s12931-019-1181-0
Molecular epidemiological study of enterovirus D68 in hospitalised children in Hong Kong in 2014-2015 and their complete coding sequences
Haichao Wang, Kin Pong Tao, Cheuk Yin Leung, Kam Lun Hon, Apple CM Yeung, Zigui Chen, Paul KS Chan, Ting-Fan Leung, Renee WY Chan ( 2019 )
BMJ Open Respiratory Research
Publication in refereed journal
典藏於此文庫的全文:
e000437.full.pdf
數位物件識別號 (DOI): http://dx.doi.org/10.1136/bmjresp-2019-000437
Non-human Primate Papillomaviruses Share Similar Evolutionary Histories and Niche Adaptation as the Human Counterparts
Chen Zigui, Long Teng, Wong Po Yee, Ho Wendy C.S., Burk Robert D., Chan Paul K.S. ( 2019 )
Frontiers in Microbiology
Publication in refereed journal
典藏於此文庫的全文:
fmicb-10-02093.pdf
數位物件識別號 (DOI): http://dx.doi.org/10.3389/fmicb.2019.02093
Norovirus-induced immune response in human intestinal enteroids
Chan J, Mohammad K, Zhang L, Wong S, Chan M ( 2019 )
Refereed conference paper presented and published in conference proceedings
Norovirus Virus-like Particles - Good Surrogates for Native Virions in Binding Analyses?
Martin Chi-Wai Chan, Sarah K.C. Cheung ( 2019 )
Refereed conference paper presented and published in conference proceedings
Novel N-Substituted oseltamivir derivatives as potent influenza neuraminidase inhibitors: Design, synthesis, biological evaluation, ADME prediction and molecular docking studies
J Ye, X Yang, M Xu, PK Chan, C Ma ( 2019 )
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.ejmech.2019.111635
Nusbiarylins, a new class of antimicrobial agents: Rational design of bacterial transcription inhibitors targeting the interaction between the NusB and NusE proteins
Qiu Y, Chan ST, Lin L, Shek TL, Tsang TF, Zhang Y, Ip M, Chan PK, Blanchard N, Hanquet G, Zuo Z, Yang X, Ma C ( 2019 )
Bioorganic Chemistry
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.bioorg.2019.103203
Oncogenic comparison of human papillomavirus type 58 E7 variants
Priscilla TY Law, Siaw Shi Boon, Chenghua Hu, Raymond WM Lung, Grace PY Cheung, Wendy CS Ho, Zigui Chen, Paola Massimi, Miranda Thomas, David Pim, Lawrence Banks, Paul KS Chan ( 2019 )
Journal of cellular and molecular medicine
Publication in refereed journal
典藏於此文庫的全文:
Law_et_al-2019-Journal_of_Cellular_and_Molecular_Medicine.pdf
數位物件識別號 (DOI): http://dx.doi.org/10.1111/jcmm.14059
Oncogenicitiy Comparison of Human Papillomavirus Type 52 E6 Variants
Lai, Boon, Law, Chen, Thomas, Banks, Chan ( 2019 )
The Journal of general virology
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1099/jgv.0.001222
Oncogenic role of human papillomavirus type 58 E7 variants
Siaw Shi Boon, Priscilla TY Law, Chenghua Hu, Raymond WM Lung, Grace PY Cheung, Wendy CS Ho, Zigui Chen, Paola Massimi, Miranda Thomas, David Pim, Lawrence Banks, Paul KS Chan ( 2019 )
Refereed conference paper presented and published in conference proceedings
Optimal gender-specific age for cost-effective vaccination with adjuvanted herpes zoster subunit vaccine in Chinese adults
Joyce H. S. You, Wai-kit Ming, Owen Tak-yin Tsang, Paul Kay-sheung Chan ( 2019 )
PloS one
Publication in refereed journal
典藏於此文庫的全文:
88174083.pdf
數位物件識別號 (DOI): http://dx.doi.org/10.1371/journal.pone.0210005
Pharmacokinetic interactions between metformin and berberine in rats: Role of oral administration sequences and microbiota
Yuanfeng Lyu, Yufeng Zhang, Mengbi Yang, Lin Lin, Xiao Yang, Stanley Chun Kai Cheung, Pang Chui Shaw, Paul Kay Sheung Chan, Alice Pik Shan Kong, Zhong Zuo ( 2019 )
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.lfs.2019.116818

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