Research Outputs (174)

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1,25-Dihydroxyvitamin D3 suppresses gastric cancer cell growth through VDR- and mutant p53-mediated induction of p21.
Mingxing LI, Longfei LI, Lin ZHANG, Wei HU, Jing SHEN, Zhangang XIAO, X. WU, Leung Franky CHAN, Chi Hin CHO ( 2017 )
Life sciences
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.lfs.2017.04.021
18beta-glycyrrhetinic acid protects against pyrrolizidine alkaloid-induced hepatotoxicity by inhibition of CYPs-mediated metabolic activation
ZT WANG, J MA, L ZHU, Y YE, G LIN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Adduct ion-targeted qualitative and quantitative analysis of polyoxypregnanes by ultra-high pressure liquid chromatography coupled with triple quadrupole mass spectrometry
Xu Wu, Lin Zhu, Jiang Ma, Yang Ye, Ge Lin ( 2017 )
Journal of pharmaceutical and biomedical analysis
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jpba.2017.06.038
Adequacy of Using a Three-Item Questionnaire to Determine Zygosity in Chinese Young Twins
Connie Suk-Han Ho, Mo Zheng, Bonnie Wing-Yin Chow, Simpson W. L. Wong, Cadmon K. P. Lim, Mary M. Y. Waye ( 2017 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1007/s10519-016-9826-y
Alpha-9 nicotinic acetylcholine receptors mediate hypothermic responses elicited by provocative motion in mice
Longlong TU, Lauren POPPI, John RUDD, Ethan T. CRESSWELL, Doug W. SMITH, Alan BRICHTA, Eugene NALIVAIKO ( 2017 )
Physiology & behavior
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.physbeh.2017.03.012
An abnormal TRPV4-related cytosolic Ca(2+) rise in response to uniaxial stretch in induced pluripotent stem cells-derived cardiomyocytes from dilated cardiomyopathy patients
Jun LU, Yee-Ki LEE, Xinru RAN, Wing-Hon LAI, Ronald A. LI, Wendy KEUNG, Kennis TSE, Hung-Fat TSE, Xiaoqiang YAO ( 2017 )
Biochimica et biophysica acta
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.bbadis.2017.07.021
An easily integratable behavioral system for high-throughput drug screening in zebrafish
Steven. L WALKER, Danny Cheuk-Wing CHAN, Hong-Di LIU, Wing-Ho YUNG, Ya KE ( 2017 )
Refereed conference paper presented and published in conference proceedings
Angiotensin II Type 2 Receptor Activation With Compound 21 Augments Islet Function and Regeneration in Streptozotocin-Induced Neonatal Rats and Human Pancreatic Progenitor Cells
Wang Lin, Wang Yi, Li Xingyu, Leung Po Sing ( 2017 )
PANCREAS
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1097/MPA.0000000000000754
A RasGAP, DAB2IP, regulates lipid droplet homeostasis by serving as GAP toward RAB40C
Xiaomin Luo, Chunman Li, Ran Tan, Xiaohui Xu, William K.K. Wu, Ayano Satoh, Tuanlao Wang, Sidney Yu ( 2017 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.18632/oncotarget.19960
Association of mTOR genetic variants and kidney function decline in Chinese with type 2 diabetes: The Hong Kong Diabetes Registry (HKDR)
Lee-Ling Lim, Katie K.H. Chan, Ronald C.W. Ma, Eric S.H. Lau, Claudia H.T. Tam, Guozhi Jiang, Heung-Man Lee, Cadmon K.P. Lim, Alex C.W. Ng, Risa Ozaki, Andrea O.Y. Luk, Juliana C.N. Chan, Alice P.S. Kong ( 2017 )
Other conference paper
Association of mTOR genetic variants with anthropometric traits in Hong Kong Chinese with type 2 diabetes
Lee-Ling Lim, Katie K.H. Chan, Ronald C.W. Ma, Eric S.H. Lau, Claudia H.T. Tam, Guozhi Jiang, Heung-Man Lee, Cadmon K.P. Lim, Risa Ozaki, Andrea O.Y. Luk, Juliana C.N. Chan, Alice P.S. Kong ( 2017 )
Other conference paper
A thirty-year quest for a role of R-Ras in cancer: from an oncogene to a multitasking GTPase
LIU Wai Nam, YAN Mingfei, CHAN Man Lok Andrew ( 2017 )
Cancer letters
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.canlet.2017.06.003
Beta-amyloid in the Gastrointestinal Tract May Cause Cognitive Deficits: Protective Action of Soy Flavonoids
Julia Y.H. Liu, Ge Lin and John A. Rudd ( 2017 )
Other conference paper
Bi-directionally protective communication between neurons and astrocytes under ischemia.
Xiao-Mei WU, Christopher QIAN, Yu-Fu ZHOU, Yick-Chun YAN, Qian-Qian LUO, Wing-Ho YUNG, Fa-Li ZHANG, Li-Rong JIANG, Zhong Ming QIAN, Ya KE ( 2017 )
Redox biology
Publication in refereed journal
View Full-text in CUHK:
10.1016_j.redox.2017.05.010.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.redox.2017.05.010
Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species
Li MY, Song LH, Yue GGL, Lee JKM, Zhao LM, Li L, Zhou XN, Tsui SKW, Ng SSM, Fung KP, Tan NH, Lau CBS ( 2017 )
SCIENTIFIC REPORTS
Publication in refereed journal
View Full-text in CUHK:
10.1038_srep42176.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1038/srep42176
Biomarker development and risk assessment of P450-mediated metabolism of pyrrolizidine alkaloids induced livery injury
Jiang MA, Mengbi YANG, Jianqing RUAN, Ge LIN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Bmal1 Deficiency in Myeloid Cells Promotes Hypertension and Hypertension-associated Renal and Vascular Inflammation in Mice
Mingyu HUO, Danyang TIAN, Chi Wai LAU, Hongsong ZHANG, Ajay CHAWLA, Yu HUANG, Xiao Yu TIAN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Brain Activation by H-1 Antihistamines Challenges Conventional View of Their Mechanism of Action in Motion Sickness: A Behavioral, c-Fos and Physiological Study in Suncus murinus (House Musk Shrew)
Longlong TU, Zengbing LU, Karolina Dieser, Christina Schmitt, Sze Wa Chan, Man P. Ngan, Paul L. R. Andrews, Eugene Nalivaiko, John A. Rudd ( 2017 )
FRONTIERS IN PHYSIOLOGY
Publication in refereed journal
View Full-text in CUHK:
10.3389_fphys.2017.00412.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.3389/fphys.2017.00412
BRE modulates granulosa cell death to affect ovarian follicle development and atresia in the mouse
Cheung Kwan YEUNG, Guang WANG, Yao YAO, Jianxin LIANG, Cheuk Yiu Tenny CHUNG, Manli CHUAI, Kenneth Ka Ho LEE, Xuesong YANG ( 2017 )
CELL DEATH & DISEASE
Publication in refereed journal
View Full-text in CUHK:
41370978.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1038/cddis.2017.91
Cathelicidin-encoding Lactococcus lactis promotes mucosal repair in murine experimental colitis
Wong CM, Zhang Lin, Wu William KK, Shen Jing, Chan Ruby LY, Lu Lan, Hu Wei, Li MingX, Li LongF, Ren ShunX, Li YiF, Li Jiang, Cho ChiH ( 2017 )
Journal of Gastroenterology and Hepatology
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1111/jgh.13499
CD147 regulates extrinsic apoptosis in spermatocytes by modulating NFκB signaling pathways
WANG Chaoqun, FOK Kin Lam, CAI Zhiming, CHEN Hao, CHAN Hsiao Chang ( 2017 )
Oncotarget
Publication in refereed journal
View Full-text in CUHK:
10.18632_oncotarget.13624.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.18632/oncotarget.13624
CFTR-β-catenin interaction regulates mouse embryonic stem cell differentiation and embryonic development
Zhengqing LIU, Jinghui GUO, Yan WANG, Zhihui WENG, Biao HUANG, Mei Kuen YU, Xiaohu ZHANG, Ping YUAN, Hui ZHAO, Wai Yee CHAN, Xiaohua JIANG, Hsiao Chang CHAN ( 2017 )
Cell death and differentiation
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1038/cdd.2016.118
Chronic liver injury induced by pyrrolizidine alkaloids
Xinmeng CHEN, Jiang MA, Qihe XU, Ge LIN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Co-culture of Human Fetal Bone Marrow-Derived Mesenchymal Stem Cells Promotes the Proliferation and Differentiation of Human Pancreatic Progenitor Cells into Islet-like Cell Clusters
Li X, Wu S, Leung PS ( 2017 )
Other conference paper
Collapsin response mediator protein-1 (CRMP1) acts as an invasion and metastasis suppressor of prostate cancer via its suppression of epithelial–mesenchymal transition and remodeling of actin cytoskeleton organization
Cai G., Wu D., Wang Z., Xu Z., Wong K.-B., Ng C.-F., Chan F.L., Yu S. ( 2017 )
Oncogene
Publication in refereed journal
View Full-text in CUHK:
onc2016227.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1038/onc.2016.227
Comparison of Brain- and Non-brain Penetrating Anti-histamines Against Motion-induced Emesis in Suncus Murinus (House Musk Shrew)
Longlong TU, John A. RUDD ( 2017 )
Other conference paper
Comparison of Brain-and non-brain Penetrating Anti-Histamines Against Motion-induced Emesis in Suncus Murinus (House Musk Shrew)
Tu Longlong, Rudd John A. ( 2017 )
Other conference paper
Comprehensive Analysis of Acylcarnitine Species in db/db Mouse Using a Novel Method of High-Resolution Parallel Reaction Monitoring Reveals Widespread Metabolic Dysfunction Induced by Diabetes
Li Xiang, Juntong Wei, Xiao Yu Tian, Bei Wang, Wan Chan, Shangfu Li, Zhi Tang, Hongsong Zhang, Wai San Cheang, Qian Zhao, Hongzhi Zhao, Zhiyi Yang, Yanjun Hong, Yu Huang, Zongwei Cai ( 2017 )
Analytical chemistry
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1021/acs.analchem.7b02283
COPI-TRAPPII activates Rab18 and regulates its lipid droplet association
LI Chunman, LUO Xiaomin, ZHAO Shan, SIU Gavin K.Y., LIANG Yongheng, CHAN Hsiao Chang, SATOH Ayano, YU Siu Bun Sidney ( 2017 )
EMBO JOURNAL
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.15252/embj.201694866
CRISPR/Cas9-mediated gene correction in iPSCs derived from Dominant megacolon mouse skin fibroblasts
Yuejiao LI, Bo FENG, Hui ZHAO, Wood Yee CHAN ( 2017 )
Refereed conference paper presented and published in conference proceedings
CRISPR/Cas9-mediated Knock-in of Large DNA in Human Cells
Xiangjun HE, Bo FENG ( 2017 )
Other conference paper
CRISPR/Cas9-mediated Knock-in of Large DNA in Human Cells
Xiangjun HE, Bo FENG ( 2017 )
Other conference paper
CRISPR/Cas9 Technology Targeting Fas Gene Protects Mice From Concanavalin-A Induced Fulminant Hepatic Failure
Wei-Cheng Liang, Pu-Ping Liang, Cheuk-Wa Wong, Tzi-Bun Ng, Jun-Jiu Huang, Jin-Fang Zhang, Mary Miu-Yee Waye, Wei-Ming Fu ( 2017 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1002/jcb.25722
CRISPR / Cas9 介导的非同源性外源DNA 在基因组中的高效敲入
Xiangjun HE, Bo FENG ( 2017 )
Other conference paper
Critical Role of Vitamin D3 in Helicobacter pylori Eradication in Stomachs
Hu W, Cho CH ( 2017 )
Other conference paper
Defective autophagy participates in endothelial dysfunction in diabetic mice
Lei ZHAO, Jian LIU, Li WANG, Jiang-Yun LUO, Lingshan GOU, Chi Wai LAU, Xiao Yu TIAN, Yu HUANG ( 2017 )
Other conference paper
Deficiency in retinoic acid leads to inborn nephron deficit in offspring exposed to diabetes in utero
A.S.W. SHUM, S.T.K. TAM, L.M.Y. LEE, A.S. WOOLF, P.J. MCCAFFERY ( 2017 )
Refereed conference paper presented and published in conference proceedings
Digital Object Identifier (DOI): http://dx.doi.org/10.1017/S2040174417000848
Delineating the epigenetic regulation of myeloid derived suppressor cell generation in hepatocellular carcinoma associated with cirrhosis
Man Liu, Jingying Zhou, John Wong, Anthony W.H. Chan, Zhiwei Chen, Alfred Sze Lok Cheng ( 2017 )
Refereed conference paper presented and published in conference proceedings
Development and characterization of a bone-targeting small molecule drug delivery system
Zeru TIAN, Fengjie ZHANG, Chao WAN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Development of hyaluronic acid-based drug delivery system for promoting articular cartilage repair
Lin WANG, Wing Pui TSANG, Fengjie ZHANG, Chi WU, Chao WAN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Development of iPSC-induced Neural Crest Cells and Enteric Neural Crest Stem Cells in the Gut Following Transplantation
Allan LUI, Yuzhe NIU, Wood Yee CHAN ( 2017 )
Other conference paper
Discovery of a Novel HIV-1 Integrase/p75 Interacting Inhibitor by Docking Screening, Biochemical Assay, and in Vitro Studies
Yan WANG, Huang-Quan LIN, Ping WANG, Jian-Shu HU, Tsz-Ming IP, Liu-Meng YANG, Yong-Tang ZHENG,
David Chi-Cheong WAN ( 2017 )
JOURNAL OF CHEMICAL INFORMATION AND MODELING
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1021/acs.jcim.7b00402
Disruption of enhancer network prevent MDSC generation and promote mature myeloid cell differentiation
Liu M, Cheng SL, Zhou J, Wu F ( 2017 )
Other conference paper
Effects of a lower-limb exoskeleton on muscle synergies in healthy and chronic stroke patients
L. RINALDI, L. YEUNG, P. LAM, M. PANG, R. TONG, V. CHEUNG ( 2017 )
Refereed conference paper presented and published in conference proceedings
Effects of neonatal maternal separation on the colonic motility and enteric nervous system of adult rats
Bo LI, Cynthia Kwan Yui CHEUNG, John Anthony RUDD, Justin Che Yuen WU, Wood Yee CHAN ( 2017 )
Other conference paper
Effects of PTEN localization and phosphatase activity on gene expression profiling of glioblastoma cells
Wang Yubing, Chan Man Lok Andrew ( 2017 )
Other conference paper
Empowering liver cancer immunotherapy by specific inhibition of histone deacetylase 8
Alfred Sze Lok CHENG, Weiqin YANG, Yu FENG, Jingying ZHOU, Hangyong SUN, Zhiwei CHEN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Endothelial Smad4 Contributes to Beiging of White Adipose Tissue by Regulating Angiogenesis and Adipogenic Precursor Proliferation
Xiao Yu TIAN, Hongsong ZHANG, Chenguang WANG, Mingyu HUO, Ronald C. MA, Yu HUANG ( 2017 )
Refereed conference paper presented and published in conference proceedings
Enhanced Hematopoietic Stem Cell Self-Renewal-Promoting Ability of Clonal Primary Mesenchymal Stromal/Stem cells Versus Their Osteogenic Progeny
Qiling He, Claude Scott Swindle, Chao Wan, Robert J. Flynn, Robert A. Oster, Dongquan Chen, Fengjie Zhang, Yinglan Shu, Christopher A. Klug ( 2017 )
STEM CELLS
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1002/stem.2481
Epigenetic Modification of the CCL5/CCR1/ERK Axis Enhances Glioma Targeting in Dedifferentiation-Reprogrammed BMSCs
Chen R, Lee Wayne YW, Zhang XH, Zhang JT, Lin S, Xu LL, Huang B, Yang FY, Liu HL, Wang B, Tsang LL, Willaime-Morawek S, Li G, Chan HC, Jiang X ( 2017 )
STEM CELL REPORTS
Publication in refereed journal
View Full-text in CUHK:
10.1016_j.stemcr.2017.01.016.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.stemcr.2017.01.016
Epigenomic profiling of primary hepatocellular carcinoma reveals super-enhancer-associated chromatin regulator network
Liangliang XU, Feng WU, Otto K.W. CHEUNG, Lemuel L.M. SZETO, Myth T.S. MOK, Alfred S.L. CHENG ( 2017 )
Refereed conference paper presented and published in conference proceedings
Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Upregulates Glucose Transporter 1 Transcription via the mTORC1/NF-κB Signaling Pathways
Zhang J, Jia L, Lin W, Yip YL, Lo KW, Lau VM, Zhu D, Tsang CM, Zhou Y, Deng W, Lung HL, Lung ML, Cheung LM, Tsao SW ( 2017 )
Journal of virology
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1128/JVI.02168-16
Eradication of hepatocellular carcinoma by augmenting PD-L1 blockade efficacy with suppression of cell-cycle related kinase (CCRK)-induced myeloid-derived suppressor cells
ZHOU Jingying, LIU Man, SUN Hangyong, FENG Yu, WONG John, CHAN Anthony W.H., CHOW King-Lau, CHEN Zhiwei, CHENG Alfred S.L. ( 2017 )
The Journal of Immunology
Publication in refereed journal
Eriocalyxin B, a novel autophagy inducer, exerts anti-tumor activity through the suppression of Akt/mTOR/p70S6K signaling pathway in breast cancer.
ZHOU Xunian, YUE Gar-Lee Grace, CHAN Man Lok Andrew, TSUI Kwok Wing, FUNG Kwok Pui, SUN Handong, PU Jianxin, LAU Clara Bik San ( 2017 )
Biochemical pharmacology
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.bcp.2017.06.133
Evaluation of progressive hepatotoxicity induced by chronic exposure to pyrrolizidine alkaloids
Yisheng HE, Jiang MA, Yang YE, Ge LIN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Exome and Genome Sequencing of Nasopharynx Cancer Identifies NF-kB Pathway Activating Mutations
Yvonne Y Li, Grace Tin-Yun Chung, Vivian W.Y. Lui, Ka-Fai To, Brigette Buig-Yue Ma, Chit Chow, John Kong-Sang Woo, Kevin Y. Yip, Jeongsun Seo, Edwin Pun Hui, Michael Ko-Fung Mak, Maria Rusan, Nicole G. Chau, Yvonne Yan-Yan Or, Marcus Hung-Nam Law, Peggy Pui-Ying Law, Zoey Wing-Yee Liu, Hoi Lam Ngan, Krista R. Verhoeft, Peony H.Y. Poon, Seong-Keun Yoo, Jong-Yeon Shin, Sau-Dan Lee, Samantha Wei-Man Lun, Anthony Wing-Hung Chan, Jason Ying-Kuen Chan, Paul Bo-San Lai, Choi-Yi Fung, Suet-Ting Hung, Lin Wang Lin, Ann Margaret V. Chang, Simion I. Chiosea, Matthew Louis Hedberg, Sai-Wah Tsao, Charles Andrew van Hasselt, Anthony Tak-Cheung Chan, Jennifer R. Grandis, Peter S. Hammerman, Kwok-Wai Lo ( 2017 )
Publication in refereed journal
View Full-text in CUHK:
ncomms14121.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1038/ncomms14121
Expression of Iron Transporters and Pathological Hallmarks of Parkinson's and Alzheimer's Diseases in the Brain of Young, Adult, and Aged Rats
Li-Na Lu, Zhong-Ming Qian, Ka-Chun Wu, Wing-Ho Yung, Ya Ke ( 2017 )
Molecular neurobiology
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1007/s12035-016-0067-0
FGF21/analogue suppresses high-fat diet induced islet cell dysfunction and cell apoptosis in mice
Ting XIE, Po Sing LEUNG ( 2017 )
Other conference paper
FGF21
Tsz Wai CHENG, Po Sing LEUNG ( 2017 )
Chapter in an edited book (author)
Digital Object Identifier (DOI): http://dx.doi.org/10.1007/978-1-4614-6438-9_101992-1
Fibroblast Growth Factor 21: A Regulator of Metabolic Disease and Health Span
Ting XIE, Po Sing LEUNG ( 2017 )
American Journal of Physiology - Endocrinology and Metabolism
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1152/ajpendo.00101.2017
First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans
Mengbi YANG, Jianqing RUAN, Hong GAO, Na LI, Jiang MA, Junyi XUE, Yang YE, Peter Pi‑Cheng FU, Jiyao WANG, Ge LIN ( 2017 )
Archives of Toxicology
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1007/s00204-017-2013-y
Follistatin-like 1 (FSTL1) Increases Transepithelial Resistance in Kidney Epithelial Cells
Zhang Y, Huang H, Liu W, Xia Y ( 2017 )
Refereed conference paper presented and published in conference proceedings
Follistatin-like protein 1 increases transepithelial resistance in kidney epithelial cells through Akt signaling
Fei CHEN, Qiang HU, Huihui HUANG, Binbin CHEN, Yin XIA, Wenjing LIU ( 2017 )
MOLECULAR MEDICINE REPORTS
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.3892/mmr.2017.7113
Gastrodin Inhibits Store-Operated Ca(2+) Entry and Alleviates Cardiac Hypertrophy
Changbo Zheng, Chun-Yin Lo, Zhaoyue Meng, Zhichao Li, Mingkui Zhong, Peng Zhang, Jun Lu, Zhaoxiang Yang, Fuman Yan, Yunting Zhang, Yu Huang, Xiaoqiang Yao ( 2017 )
Frontiers in pharmacology
Publication in refereed journal
View Full-text in CUHK:
fphar-08-00222.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.3389/fphar.2017.00222
Gene correction of a Sox10 mutation in mouse iPSCs using CRISPR/Cas9 gene editing system
LI Yuejiao, FENG Bo, CHAN Wood Yee ( 2017 )
Other conference paper
Generation and characterization of bio-ink for 3D bioprinting
Tak Keung PANG, Chao WAN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Generation and characterization of bioink for 3D bioprinting
Tak Keung PANG, Chao WAN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Generation of a Bag1 homozygous knockout mouse embryonic stem cell line using CRISPR/Cas9
Cheng-cheng Tanga, Li Pik Shan, Wu-ming Wang, Gang Lu, Rahul S. Tare, Kenneth Ka Ho Lee ( 2017 )
Stem Cell Research
Publication in refereed journal
View Full-text in CUHK:
10.1016_j.scr.2017.03.016.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.scr.2017.03.016
Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells
Yang, Wang, Zhou, Wong, Tian, Hong, Lai, Au, Wei, Liu, Cheng, Liang, Huang, Fan, Zhao, Wang, Ibañez, Luo, Li, Zhong, Chen, Wang, Li, Lai, Qin, Bao, Hutchins, Siu, Huang, Esteban, Tse ( 2017 )
Stem cell reports
Publication in refereed journal
View Full-text in CUHK:
10.1016 j.stemcr.2017.01.027.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.stemcr.2017.01.027
Generation of novel hyaluronic acid-based biodegradable functional scaffolds for cartilage tissue engineering
Lin WANG, Wing Pui TSANG, Fengjie ZHANG, Chi WU, Chao WAN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Germline-specific dgcr8 knockout in zebrafish using a BACK approach
Yun Liu, Zeyao Zhu, Idy H. T. Ho, Yujian Shi, Yuxin Xie, Jianzhen Li, Yong Zhang, Matthew T. V. Chan, Christopher H. K. Cheng ( 2017 )
Cellular and molecular life sciences : CMLS
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1007/s00018-017-2471-7
GLP-1 Receptor Agonist Exenatide Attenuates Endothelial Dysfunction by Reducing Oxidative Stress in Hyperhomocysteinemia via AMPK/eNOS Pathway
Chak Kwong CHENG, Chi Wai LAU, Xiaoyu TIAN, Yu HUANG ( 2017 )
Other conference paper
GPR120 mediated pdx1 signaling protects against palmitic acid-induced pancreatic beta-cell dysfunction
Yi WANG, Po Sing LEUNG ( 2017 )
Other conference paper
GPR120
Yi WANG, Po Sing LEUNG ( 2017 )
Chapter in an edited book (author)
Digital Object Identifier (DOI): http://dx.doi.org/10.1007/978-1-4614-6438-9_101625-1
Growth Horomone Releasing-hormone Receptor (GHRHR) Antagonist Inhibits Synthesis and Secretion of Pro-Inflammatory Cytokines in Explant Cultures of Rat Iris and Ciliary Body During Lipopolysaccharide-induced Inflammation
Jialin REN, Sun On CHAN, Puiying LEUNG, Calvin PANG, Qiuxiao YU ( 2017 )
Refereed conference paper presented and published in conference proceedings
HDAC8 inhibition modulates liver tumor microenvironment: Rationale for combined epigenetic and immunotherapy
CHENG Alfred Sze Lok, FENG Yu, ZHOU Jingying, YANG Weiqin, SUN Hangyong, CHEN Zhiwei, TYLER Goodwin, LIU Rihe, HUANG Leaf ( 2017 )
The Journal of Immunology
Invited conference paper presented and published in conference proceedings
HDAC8 inhibition modulates liver tumor microenvironment: Rationale for combined epigenetic and immunotherapy
CHENG Alfred Sze Lok, FENG Yu, ZHOU Jingying, YANG Weiqin, SUN Hangyong, CHEN Zhiwei, TYLER Goodwin, LIU Rihe, HUANG Leaf ( 2017 )
The Journal of Immunology
Refereed conference paper presented and published in conference proceedings
Hepatic KLF2 Regulates Lipid Metabolism in Obese Mice
Huang Yuhong, Tian Xiao Yu, Huo Mingyu, Luo Jiangyun, Huang Yu ( 2017 )
Other conference paper
Hepatotoxicity induced by pyrrolizidine alkaloids and pyrrolizidine alkaloid n-oxides
Mengbi YANG, Jianqing RUAN, Ge LIN ( 2017 )
Refereed conference paper presented and published in conference proceedings
HIF-1α signaling in osteoblast regulates B lineage differentiation
Shuang LIANG, Qiling HE, Fengjie ZHANG, Wing Pui TSANG, Christopher A KLUG, Chao WAN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Histone Deacetylase Inhibitors Relax Mouse Aorta Partly through Their Inhibitory Action on L-Type Ca2+ Channels
Changbo ZHENG, Mingkui ZHONG, Zenghua QI, Fan SHEN, Qiannan ZHAO, Lulu WU, Yu HUANG, Suk-
Ying TSANG, Xiaoqiang YAO ( 2017 )
The Journal of pharmacology and experimental therapeutics
Publication in refereed journal
View Full-text in CUHK:
10.1124_jpet.117.242685.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1124/jpet.117.242685
Hypoxia regulates collagen type II secretion through autophagy-lysosome degradation pathway
Yichen ZHAO, Chao WAN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Identification and Functional Implications of Sodium/Myo-Inositol Cotransporter 1 in Pancreatic β-Cells and Type 2 Diabetes
Li SYT, Cheng STW, Zhang D, Leung PS ( 2017 )
Diabetes
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.2337/db16-0880
Identification of de novo genetic targets associated with natural & accelerated ageing by single-cell whole exome sequencing
Qian Y., Liao J., Zeng X., Chi L., Chung C. H., Kong G. W., Leung T. Y., Chan W. Y., Li T. C., Lee T. L. ( 2017 )
Other conference paper
Identification of Genes Associated with Pancreatic Cancer Metastasis by Genome-wide CRISPR Cas9 Screening
Li YJ, Feng HY, Liu GJ, Wong CH, Li CH, Chen YC ( 2017 )
Refereed conference paper presented and published in conference proceedings
Identifying super enhancer-associated master transcription factors in primary human hepatocellular carcinoma
Otto Ka-Wing CHEUNG, Feng WU, Sau Dan LEE, Patrick TAN, Kevin Yuk-Lap YIP, Alfred S CHENG ( 2017 )
Refereed conference paper presented and published in conference proceedings
Identifying super enhancer-associated master transcription factors in primary human hepatocellular carcinoma
Otto Ka-Wing CHEUNG, Feng WU, Sau Dan LEE, Patrick TAN, Kevin Yuk-Lap YIP, Alfred S CHENG ( 2017 )
Refereed conference paper presented and published in conference proceedings
Immunoassay approach for diagnosis of exposure to pyrrolizidine alkaloids
LI Na, ZHANG Fan, LIAN Wei, WANG Huali, ZHENG Jiang, LIN Ge ( 2017 )
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1080/10590501.2017.1328828
Impact of Treadmill Exercise on Endothelial Function during Estrogen Deficiency in Ovariectomized db/db female Mice
Wencong SONG, Yu HUANG ( 2017 )
Refereed conference paper presented and published in conference proceedings
Incidence of Hepatotoxic Pyrrolizidine Alkaloid Contamination in Retail Honey
He Yi-Sheng and Lin Ge ( 2017 )
Other conference paper
Induction of mouse neural crest cells from induced pluripotent stem cells in vitro
NIU Yuzhe, FENG Bo, ZHAO Hui, SHAM Mai Har, CHAN Wood Yee ( 2017 )
Other conference paper
Inhibition of ovulation in zebrafish by microRNA
Wen XU, Zeyao ZHU, Jianzhen LI, Christopher H.K. CHENG ( 2017 )
Refereed conference paper presented and published in conference proceedings
Insulinotropic effects of GPR120 agonists are altered in obese diabetic and obese non-diabetic states
Dan Zhang, Wing Yan So, Yi Wang, Shang Ying Wu, Qianni Cheng, Po Sing Leung ( 2017 )
CLINICAL SCIENCE
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1042/CS20160545
Integrative epigenomic analysis of functional enhancers in liver carcinogenesis
Lei XIONG, Wei KANG, Qiong WU, Feng WU, Raymond W. LUNG, Ken H. YU, Sau-Dan LEE, Joseph LIU, Guangcun HUANG, Chiou-Miin WANG, Jian-Liang ZHOU, Michael W. CHAN, Nathalie WONG, Tim H. HUANG, Kevin Y. YIP, Alfred S. CHENG, Ka F. TO ( 2017 )
Refereed conference paper presented and published in conference proceedings
Intermittent vibration protects aged muscle from mechanical and oxidative damage under prolonged compression
Sing Wan WONG, Brian Chun Ho CHEUNG, Bruce Tak Keung PANG, Ateline KWONG, Anna CHUNG, Kenneth Ka Ho LEE, Arthur Fut Tak MAK ( 2017 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jbiomech.2017.02.023
Investigating the Mechanisms of Tumor Suppression Mediated by PTEN PDZ-binding Domain in a Murine Breast Cancer Model
Yan MF, Many A, Guan H, Or, MY, Chan ML ( 2017 )
Other conference paper
Investigation of Pyrrolizidine Alkaloid-Induced Pulmonary Toxicity
Lian Wei, Ma Jiang, Wong Chi-Wai, Zhu Lin, Lin Ge ( 2017 )
Refereed conference paper presented and published in conference proceedings
Investigation of the Mechanism Initiating Pyrrolizidine Alkaloid-induced Pulmonary Vascular Remodeling
Wei LIAN, Jiang MA, Lin ZHU, Ge LIN ( 2017 )
Refereed conference paper presented and published in conference proceedings
Investigation of the Slitrk6 function in the enteric nervous system development of Sox10 mutant Dominant megacolon mouse
Taida HUANG, Tiantian PAN, Yonghui HOU, Wood Yee CHAN ( 2017 )
Other conference paper
Involvement of TM9SF4 in Actin Cytoskeleton Function in Breast Cancer Cells
Yifei ZHU, Xiaoqiang YAO ( 2017 )
Refereed conference paper presented and published in conference proceedings

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