Research Outputs (51)

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ZBP-89 reduces histone deacetylase 3 by degrading IkappaB in the presence of Pin1
Cai Guo Ye, Liping Liu, George G Chen, Xiao Lin Tang, Zhiwei He, Ming-Liang He, Paul BS Lai ( 2015 )
Journal of Translational Medicine
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1186/s12967-015-0382-7
Yoga for secondary prevention of coronary heart disease
Kwong JSW, Lau HLC, Yeung F, Chau PH, Woo J ( 2015 )
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1002/14651858.CD009506.pub3
Truncated HBx-dependent silencing of GAS2 promotes hepatocarcinogenesis through deregulation of cell cycle, senescence and p53-mediated apoptosis
Zhu RX, Mok MTS, Kang W, Lau SSK, Yip WK, Chen YC, Lai PBS, Wong VWS, To KF, Sung JJY, Cheng ASL, Chan HLY ( 2015 )
JOURNAL OF PATHOLOGY
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1002/path.4554
The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling
Wang CD, Kam RKT, Shi WL, Xia Y, Chen XF, Cao Y, Sun JM, Du YZ, Lu G, Chen ZJ, Chan WY, Chan SO, Deng Y, Zhao H ( 2015 )
JOURNAL OF BIOLOGICAL CHEMISTRY
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1074/jbc.M115.644864
The Choice of Mitral Annuloplastic Ring – Beyond “Surgeon’s Preference"
WAN Song, LEE Pui-Wai Alex, JIN, Chunna 金春娜, WONG H. L. Randolph, CHAN H M Herman, NG Sze Hang Calvin, WAN Y P Innes, UNDERWOOD Malcolm John ( 2015 )
Annals of Cardiothoracic Surgery
Publication in refereed journal
Targeting of YAP1 by microRNA-15a and microRNA-16-1 exerts tumor suppressor function in gastric adenocarcinoma
Kang W, Tong JHM, Lung RWM, Dong YJ, Zhao JH, Liang QY, Zhang L, Pan Y, Yang WQ, Pang JCS, Cheng ASL, Yu J, To KF ( 2015 )
MOLECULAR CANCER
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1186/s12943-015-0323-3
Serrated polyps and the risk of synchronous colorectal advanced neoplasia: A systematic review and meta-analysis
Gao Q., Tsoi K.K.F., Hirai H.W., Wong M.C.S., Chan F.K.L., Wu J.C.Y., Lau J.Y.W., Sung J.J.Y., Ng S.C. ( 2015 )
American Journal of Gastroenterology
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1038/ajg.2015.49
Risk factors for incident dementia after stroke and transient ischemic attack
Yang J, Wong A, Wang ZL, Liu WY, Au L, Xiong YY, Chu WWC, Leung EYL, Cheng SR, Lau C, Chan AYY, Lau AYL, Fan F, Ip V, Soo Y, Leung T, Ho CL, Wong LKS, Mok VCT ( 2015 )
Alzheimers & Dementia
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jalz.2014.01.003
Relationships between Sleep Behaviors and Unintentional Injury in Southern Chinese School-Aged Children: A Population-Based Study
Tan YF, Ma D, Chen Y, Cheng FY, Liu XX, Li LP ( 2015 )
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.3390/ijerph121012999
Reduced striatal dopamine transmission in REM sleep behavior disorder comorbid with depression
Wing YK, Lam SP, Zhang JH, Leung E, Ho CL, Chen SR, Cheung MK, Li SX, Chan JWY, Mok V, Tsoh J, Chan A, Ho CKW ( 2015 )
NEUROLOGY
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1212/WNL.0000000000001215
Pulse Pressure and Cognitive Decline in Stroke Patients With White Matter Changes
Zhaolu Wang, Adrian Wong, Wenyan Liu, Jie Yang, Winnie C.W. Chu, Lisa Au, Alexander Lau, Yunyun Xiong, Vincent C.T. Mok ( 2015 )
Journal of Clinical Hypertension
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1111/jch.12583
Pharmacogenetics of cutaneous flushing response to niacin/ laropiprant combination in Hong Kong Chinese patients with dyslipidemia
Hu M, Yang YL, Chan P, Tomlinson B ( 2015 )
PHARMACOGENOMICS
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.2217/PGS.15.79
Personalized Medicine for Severe Asthma: How Far Have We Achieved?
LEUNG Ting Fan, TANG, Man Fung, WONG Wing Kin Gary ( 2015 )
Journal of Pharmacogenomics & Pharmacoproteomics
Publication in refereed journal
Patient acceptability, efficacy, and skin biophysiology of a cream and cleanser containing lipid complex with shea butter extract versus a Ceramide product for eczema
Hon K.L., Tsang Y.C., Pong N.H., Lee V.W.Y., Luk N.M., Chow C.M., Leung T.F. ( 2015 )
Hong Kong Medical Journal
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.12809/hkmj144472
Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer
Yu J, Wu WKK, Li XC, He J, Li XX, Ng SSM, Yu C, Gao ZB, Yang J, Li M, Wang QX, Liang QY, Pan Y, Tong JH, To KF, Wong N, Zhang N, Chen J, Lu YY, Lai PBS, Chan FKL, Li YR, Kung HF, Yang HM, Wang J, Sung JJY ( 2015 )
GUT
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1136/gutjnl-2013-306620
Novel biomarkers for the identification and targeted therapy of gastric cancer
Liu L, Cao L, Gong BA, Yu J ( 2015 )
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1586/17474124.2015.1072466
Non-linear relationship between birthweight and cardiometabolic risk factors in Chinese adolescents and adults
Tam CHT, Wang Y, Luan J, Lee HM, Luk AOY, Tutino GE, Tong PCY, Ko GTC, Ozaki R, Tam WH, Kong APS, So WY, Chan JCN, Ma RCW ( 2015 )
DIABETIC MEDICINE
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1111/dme.12630
Noninvasive assessments of liver fibrosis with transient elastography and Hui index predict survival in patients with chronic hepatitis B
Wong G.L.-H., Chan H.L.-Y., Yu Z., Wong C.K.-Y., Leung C., Ho P.P.-L., Chan C.Y., Chung V.C.-Y., Chan Z.C.-Y., Tse Y.-K., Chim A.M.-L., Lau T.K.-T., Chan H.-Y., Tse C.-H., Wong V.W.-S. ( 2015 )
Journal of Gastroenterology and Hepatology (Australia)
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1111/jgh.12779
Neuropsychiatry Syndromes Following Ischemic Stroke.
LIANG Huajun, LIANG, Yan, UNGVARI Gs, TANG Wai Kwong ( 2015 )
Neuropsychiatry Journal
Publication in refereed journal
Montreal Cognitive Assessment One Cutoff Never Fits All
Wong A, Law LSN, Liu W, Wang ZL, Lo ESK, Lau A, Wong LKS, Mok VCT ( 2015 )
STROKE
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1161/STROKEAHA.115.011226
Members of the receptor for advanced glycation end products axis as potential therapeutic targets in patients with lupus nephritis
Yu SL, Wong CK, Szeto CC, Li EK, Cai Z, Tam LS ( 2015 )
LUPUS
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1177/0961203314559631
MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome
Wang K., Liang Q., Li X., Tsoi H., Zhang J., Wang H., Go M.Y.Y., Chiu P.W.Y., Ng E.K.W., Sung J.J.Y., Yu J. ( 2015 )
Gut
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1136/gutjnl-2015-309276
Mapping the Relationship of Contributing Factors for Preclinical Alzheimer's Disease
Shi L., Zhao L., Wong A., Wang D., Mok V. ( 2015 )
Scientific Reports
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1038/srep11259
Long-term safety of oral nucleos(t)ide analogs for patients with chronic hepatitis B: A cohort study of 53,500 subjects
Wong G.L.-H., Tse Y.-K., Wong V.W.-S., Yip T.C.-F., Tsoi K.K.-F., Chan H.L.-Y. ( 2015 )
Hepatology
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1002/hep.27894
Left ventricular long-axis performance during exercise is an important prognosticator in patients with heart failure and preserved ejection fraction
Wang J, Fang F, Yip GWK, Sanderson JE, Feng W, Xie JM, Luo XX, Lee APW, Lam YY ( 2015 )
INTERNATIONAL JOURNAL OF CARDIOLOGY
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.ijcard.2014.10.130
Influence of Amyloid-β on Cognitive Decline after Stroke/Transient Ischemic Attack: Three-Year Longitudinal Study
Liu W., Wong A., Au L., Yang J., Wang Z., Leung E.Y.L., Chen S., Ho C.L., Mok V.C.T. ( 2015 )
Stroke
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1161/STROKEAHA.115.010449
IL-33 and soluble ST2 levels as novel predictors for remission and progression of carotid plaque in early rheumatoid arthritis: A prospective study
Shen JY, Shang Q, Wong CK, Li EK, Wang S, Li RJ, Lee KL, Leung YY, Ying KY, Yim CW, Kun EW, Leung MH, Li M, Li TK, Zhu TY, Yu SL, Kuan WP, Yu CM, Tam LS ( 2015 )
SEMINARS IN ARTHRITIS AND RHEUMATISM
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.semarthrit.2015.02.001
IL-33 and soluble ST2 levels as novel predictors for remission and progression of carotid plaque in early rheumatoid arthritis: A prospective study
Shen J., Shang Q., Wong C.-K., Li E.K., Wang S., Li R.-J., Lee K.-L., Leung Y.-Y., Ying K.-Y., Yim C.-W., Kun E.W., Leung M.-H., Li M., Li T.K., Zhu T.Y., Yu S.-L., Kuan W.-P., Yu C.-M., Tam L.-S. ( 2015 )
Seminars in Arthritis and Rheumatism
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.semarthrit.2015.02.001
Histone Deacetylase HDAC8 Promotes Insulin Resistance and beta-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma
Tian Y, Wong VWS, Wong GLH, Yang WQ, Sun HY, Shen JY, Tong JHM, Go MYY, Cheung YS, Lai PBS, Zhou MY, Xu G, Huang THM, Yu J, To KF, Cheng ASL, Chan HLY ( 2015 )
CANCER RESEARCH
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1158/0008-5472.CAN-14-3786
High Blood Pressure Increases the Risk of Poor Outcome at Discharge and 12-month Follow-up in Patients with Symptomatic Intracranial Large Artery Stenosis and Occlusions: Subgroup analysis of the CICAS Study
Yu D.-D., Pu Y.-H., Pan Y.-S., Zou X.-Y., Soo Y., Leung T., Liu L.-P., Wang D.Z., Wong K.-S., Wang Y.-L., Wang Y.-J. ( 2015 )
CNS Neuroscience and Therapeutics
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1111/cns.12400
Heat Shock 70-kDa Protein 5 (Hspa5) Is Essential for Pronephros Formation by Mediating Retinoic Acid Signaling
Shi WL, Xu G, Wang CD, Sperber SM, Chen YL, Zhou Q, Deng Y, Zhao H ( 2015 )
JOURNAL OF BIOLOGICAL CHEMISTRY
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1074/jbc.M114.591628
Gut Mucosal Microbiome across Stages of Colorectal Carcinogenesis
Geicho Nakatsu, Xiangchun Li, Haokui Zhou, Jianqiu Sheng, Sunny Hei Wong,William Ka Kai Wu, Siew Chien Ng, Ho Tsoi, Yujuan Dong, Ning Zhang, Yuqi He, Qian Kang, Lei Cao, Kunning Wang, Jingwan Zhang, Qiaoyi Liang, Jun Yu, Joseph J.Y. Sung ( 2015 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1038/ncomms9727
Factors associated with mucosal healing in patients with ulcerative colitis in clinical remission
Shi H.Y., Chan F.K.L., Tsang S.W.C., Hui Y.T., Sze S.F., Ching J.Y.L., Chung T., Iu C.Y.Y., Lo F.H., Shan E.H.S., Li M.K.K., Wu J.C.Y., Sung J.J.Y., Ng S.C. ( 2015 )
Inflammatory Bowel Diseases
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1097/MIB.0000000000000334
ER stress mediates homocysteine-induced endothelial dysfunction: Modulation of IKCa and SKCa channels
Wang XC, Sun WT, Yu CM, Pun SH, Underwood MJ, He GW, Yang Q ( 2015 )
ATHEROSCLEROSIS
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.atherosclerosis.2015.07.021
Effects of Phenotypic and Genotypic Factors on the Lipid Responses to Niacin in Chinese Patients With Dyslipidemia
Hu M, Yang YL, Ng CF, Lee CP, Lee VWY, Hanada H, Masuda D, Yamashita S, Tomlinson B ( 2015 )
MEDICINE
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1097/MD.0000000000000881
Effect of Extended-Release Niacin/Laropiprant Combination on Plasma Adiponectin and Insulin Resistance in Chinese Patients with Dyslipidaemia
Hu M, Yang YL, Masuda D, Yamashita S, Tomlinson B ( 2015 )
DISEASE MARKERS
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1155/2015/154014
Early diastolic dyssynchrony in relation to left ventricular remodeling and function in hypertension
Sun JP, Xu TY, Lee APW, Yang XS, Liu M, Li Y, Wang JG, Yu CM ( 2015 )
INTERNATIONAL JOURNAL OF CARDIOLOGY
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.ijcard.2014.10.158
DACT2 is a functional tumor suppressor through inhibiting Wnt/beta-catenin pathway and associated with poor survival in colon cancer
Wang S, Dong Y, Zhang Y, Wang X, Xu L, Yang S, Li X, Dong H, Xu L, Su L, Ng SSM, Chang Z, Sung JJ, Zhang X, Yu J ( 2015 )
ONCOGENE
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1038/onc.2014.201
Cortical thinning and progressive cortical porosity in female patients with systemic lupus erythematosus on long-term glucocorticoids: a 2-year case-control study
Zhu TY, Griffith JF, Qin L, Hung VWY, Fong TN, Au SK, Tang XL, Kun EW, Kwok AW, Leung PC, Li EK, Tam LS ( 2015 )
OSTEOPOROSIS INTERNATIONAL
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1007/s00198-015-3077-2
Childhood asthma is associated with polymorphic markers of PROC on 2q14 in addition to 17q21 locus
Chan WC, Sy HY, Kong APS, Wong CK, Tse LY, Hon KL, Chan JCN, Wong GWK, Leung TF ( 2015 )
PEDIATRIC ALLERGY AND IMMUNOLOGY
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1111/pai.12336
Childhood asthma and spirometric indices are associated with polymorphic markers of two vitamin D 25-hydroxylase genes
Leung TF, Wang SS, Tang MF, Kong APS, Sy HY, Hon KL, Chan JCN, Wong GWK ( 2015 )
PEDIATRIC ALLERGY AND IMMUNOLOGY
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1111/pai.12392
Characterization of the nasopharyngeal carcinoma methylome identifies aberrant disruption of key signaling pathways and methylated tumor suppressor genes
Li L., Zhang Y., Fan Y., Sun K., Su X., Du Z., Tsao S.W., Loh T.K.S., Sun H., Chan A.T.C., Zeng Y.-X., Chan W.Y., Chan F.K.L., Tao Q. ( 2015 )
Epigenomics
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.2217/EPI.14.79
Cerebrovascular Disease, Amyloid Plaques, and Dementia
Liu WY, Wong A, Law ACK, Mok VCT ( 2015 )
STROKE
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1161/STROKEAHA.114.006571
Automated quantification of mitral valve anatomy using anatomical intelligence in three-dimensional echocardiography
Jin CN, Salgo IS, Schneider RJ, Feng W, Meng FX, Kam KKH, Chi WK, So CY, Chan C, Sun JP, Tsui G, Wong KYK, Yu CM, Wan S, Wong R, Underwood M, Au S, Ng SK, Lee APW ( 2015 )
INTERNATIONAL JOURNAL OF CARDIOLOGY
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.ijcard.2015.07.018
Association between sleep architecture and glucose tolerance in children and adolescents
Zhu Y., Li A.M., Au C.T., Kong A.P.S., Zhang J., Wong C.K., Chan J.C.N., Wing Y.K. ( 2015 )
Journal of Diabetes
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1111/1753-0407.12138
Association between sleep architecture and glucose tolerance in children and adolescents
Zhu Y, Li AM, Au CT, Kong APS, Zhang JH, Wong CK, Chan JCN, Wing YK ( 2015 )
JOURNAL OF DIABETES
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1111/1753-0407.12138
A school-based sleep education program for adolescents: A cluster randomized trial
Wing Y.K., Chan N.Y., Yu M.W.M., Lam S.P., Zhang J., Li S.X., Kong A.P.S., Li A.M. ( 2015 )
Pediatrics
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1542/peds.2014-2419
Altered Sleep Stage Transitions of REM Sleep: A Novel and Stable Biomarker of Narcolepsy
Liu Y., Zhang J., Lam V., Ho C.K.W., Zhou J., Li S.X., Lam S.P., Yu M.W.M., Tang X., Wing Y.-K. ( 2015 )
Journal of Clinical Sleep Medicine
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.5664/jcsm.4940
A CCRK-EZH2 epigenetic circuitry drives hepatocarcinogenesis and associates with tumor recurrence and poor survival of patients
Feng H, Yu Z, Tian Y, Lee YY, Li MS, Go MYY, Cheung YS, Lai PBS, Chan AML, To KF, Chan HLY, Sung JJY, Cheng ASL ( 2015 )
JOURNAL OF HEPATOLOGY
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jhep.2014.11.040
Abnormal mitral–aortic intervalvular coupling in mitral valve diseases: a study using real-time three-dimensional transesophageal echocardiography
Looi J.-L., Lee A.P.-W., Fang F., Hsiung M.C., Sun J.-P., Yin W.-H., Wei J., Tsai S.-K., Wan S., Wong R.H.L., Underwood M.J., Lin Q.-S., Jin C.-N., Chen L., Yu C.-M. ( 2015 )
Clinical Research in Cardiology
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1007/s00392-015-0851-2

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Research Outputs (51)

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