研究成果 (45)

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Accurate Deducing of Fractional Fetal DNA Concentration From Massively Parallel Sequencing of DNA in Maternal Plasma Using Statistical Mixture Model
JIANG Peiyong, CHAN Allen K.c., LIAO Jiawei Gary, ZHENG Wenli, CHIU Wai Kwun Rossa, LO Yuk Ming Dennis, SUN Hao ( 2013 )
BIT’s 3rd annual world congress of MolMed-2013
Invited conference paper presented and published in conference proceedings
A novel miR-193a-5p-YY1-APC regulatory axis in human endometrioid endometrial adenocarcinoma
Yang Y, Zhou L, Lu L, Wang L, Li X, Jiang P, Chan LKY, Zhang T, Yu J, Kwong J, Cheung T, Chung T, Mak K, Sun H, Wang H ( 2013 )
ONCOGENE
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1038/onc.2012.360
A Novel PCDH10-Wnt/β-Catenin-Malat 1 Regulatory Axis in Endometrioid Endometrial Adenocarcinoma
ZHAO, Yu 趙喻, YANG Yihua, ZHOU Liang, SUN, Kun, SUN Hao, WANG Huating ( 2013 )
Noncoding RNAs in Development and Cancer
Refereed conference paper presented and published in conference proceedings
A Novel PCDH10-β-Catenin-MALAT1 Regulatory Axis in Endometriold Endometrial Carcinoma (EEC)
ZHAO, Yu 趙喻, YANG Yihua, ZHOU Liang, SUN Kun, SUN Hao, WANG Huating ( 2013 )
Epigenetic Marks and Cancer Drugs
Refereed conference paper presented and published in conference proceedings
Anti-Allergic and Anti-Inflammatory Activities of Pentaherbs Formula on Atopic Dermatitis using Novel Cell-Based System and Bioassay Guided Methods
LIU, Yan Ping Kelly, HU, SHUIQING, CHAN Chung Lap, LAU Bik San Clara, HON Kam Lun, FUNG Kwok Pui, LEUNG Ping Chung, LAM Wai Kei Christopher, WONG Chun Kwok ( 2013 )
The 20th Anniversary & 2013 Annual General Meeting and Scientific Meeting of The Hong Kong Society for Immunology
Other conference paper
Anti-Allergic and Anti-Inflammatory Activities of Pentaherbs Formula on Atopic Dermatitis using Novel Cell-Based System and Bioassay Guided Methods
LIU, Yan Ping Kelly, HU, SHUIQING, CHAN Chung Lap, LAU Bik San Clara, HON Kam Lun, FUNG Kwok Pui, LEUNG Ping Chung, LAM Wai Kei Christopher, WONG Chun Kwok ( 2013 )
The 18th Annual General Meeting and Scientific Meeting of The Hong Kong Society of Flow Cytometry
Other conference paper
Anti-Inflammatory and Anti-Allergic Activities of Pentaherb Formula, Moutan Cortex (Danpi) and Gallic Acid
Liu KYP, Hu SQ, Chan BCL, Wat ECL, Lau CBS, Hon KL, Fung KP, Leung PC, Hui PCL, Lam CWK, Wong CK ( 2013 )
MOLECULES
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.3390/molecules18032483
Anti-inflammatory effects of exendin-4, a glucagon-like peptide-1 analog, on human peripheral lymphocytes in patients with type 2 diabetes
He L, Wong CK, Cheung KKT, Yau HC, Fu A, Zhao HL, Leung KML, Kong APS, Wong GWK, Chan PKS, Xu G, Chan JCN ( 2013 )
JOURNAL OF DIABETES INVESTIGATION
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1111/jdi.12063
A Single Nucleotide Polymorphism in MicroRNA-146a Is Associated With the Risk for Nasopharyngeal Carcinoma
Lung RWM, Wang XY, Tong JHM, Chau SL, Lau KM, Cheng SH, Woo JKS, Woo J, Leung PC, Ng MHL, Tang NLS, To KF ( 2013 )
MOLECULAR CARCINOGENESIS
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1002/mc.21937
Associations of Dyslipoproteinaemia with BMI, Fasting Plasma Glucose, HbA1c, and Insulin Resistance in Chronic Kidney Disease Patients
CHU, Man, WANG Angela Yee Moon, CHAN Hiu Shuen, CHU S H, WONG Chun Kwok, LAM Wai Kei Christopher ( 2013 )
Journal of Macau University of Science and Technology
Publication in refereed journal
Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing
Chan KCA, Jiang PY, Zheng YWL, Liao GJW, Sun H, Wong J, Siu SSN, Chan WC, Chan SL, Chan ATC, Lai PBS, Chiu RWK, Lo YMD ( 2013 )
CLINICAL CHEMISTRY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1373/clinchem.2012.196014
Development and validation of a sensitive method for simultaneous determination of rosuvastatin and N-desmethyl rosuvastatin in human plasma using liquid chromatography/negative electrospray ionization/tandem mass spectrometry
Lee HK, Ho CS, Hu M, Tomlinson B, Wong CK ( 2013 )
BIOMEDICAL CHROMATOGRAPHY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1002/bmc.2944
Distinct roles of Smads and microRNAs in TGF-β signaling during kidney diseases
Li R., Lan H.Y., Chung A.C.K. ( 2013 )
Hong Kong Journal of Nephrology
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.hkjn.2013.03.003
Effect of Tumor Necrosis Factor Family Member LIGHT on the Activation of Human Bronchial Epithelial Cells
QIU, Huaina, WONG Chun Kwok, LAM Wai Kei Christopher ( 2013 )
The 20th Anniversary & 2013 Annual General Meeting and Scientific Meeting of The Hong Kong Society for Immunology
Other conference paper
Effect of Tumor Necrosis Factor Family Member LIGHT on the Activation of Human Bronchial Epithelial Cells
QIU, Huaina, WONG Chun Kwok, LAM Wai Kei Christopher ( 2013 )
The 18th Annual General Meeting and Scientific Meeting of The Hong Kong Society of Flow Cytometry
Other conference paper
Effects of polymorphisms in ABCG2, SLCO1B1, SLC10A1 and CYP2C9/19 on plasma concentrations of rosuvastatin and lipid response in Chinese patients
Lee HK, Hu M, Lui SSH, Ho CS, Wong CK, Tomlinson B ( 2013 )
PHARMACOGENOMICS
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.2217/pgs.13.115
Functional Characterization of a Large Intergenic Non-coding RNA in Muscle Stem Cells and Muscle Regeneration
ZHOU Liang, SUN Kun, CHEN Xiaona, SUN Hao, WANG Huating ( 2013 )
Myogenesis
Refereed conference paper presented and published in conference proceedings
Functional Role of Mst1/Mst2 in Embryonic Stem Cell Differentiation
Li P, Chen Y, Mak KK, Wong CK, Wang CC, Yuan P ( 2013 )
PLOS ONE
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1371/journal.pone.0079867
Functional Role of MST1/MST2 in Embryonic Stem Cell Differentiation
LI, Peng, CHEN Ying, YUAN Ping ( 2013 )
International Society for Stem Cell Research 11th Annual Meeting
Other conference paper
Genome-wide survey by ChIP-seq reveals YY1 regulation of lincRNAs in skeletal myogenesis
Lu LN, Sun K, Chen XN, Zhao Y, Wang LJ, Zhou L, Sun H, Wang HT ( 2013 )
EMBO JOURNAL
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1038/emboj.2013.182
High Resolution Profiling of Fetal DNA Clearance from Maternal Plasma
YU, Cheuk Yin Jandy, LEE Wee Yee Shara, JIANG Peiyong, LEUNG Tak Yeung, CHAN Kwan Chee, CHIU Wai Kwun Rossa, LO Yuk Ming Dennis ( 2013 )
Joint Conference of HGM 2013 and 21st International Congress of Genetics: Genetics & Genomics of Global Health and Sustainability
Refereed conference paper presented and published in conference proceedings
High-Resolution Profiling of Fetal DNA Clearance from Maternal Plasma by Massively Parallel Sequencing
Yu SCY, Lee SWY, Jiang PY, Leung TY, Chan KCA, Chiu RWK, Lo YMD ( 2013 )
CLINICAL CHEMISTRY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1373/clinchem.2013.203679
Immunopathological Roles of Pattern-recognition Receptors in Systemic Lupus Erythematosus
WONG Chun Kwok, TAM Lai Shan, YU, Shuilian, WONG Tsz Yan, CHEN Dapeng, LI Kwok Ming Edmund ( 2013 )
Autoimmunity Congress Asia 2013
Other conference paper
Impact of Statistical Analyses in the Latest Genomic Eras: from GWAS to Gene Expression
TANG Leung Sang Nelson, YEUNG, Hau Man, HU, Fuyan 胡复艷 ( 2013 )
"數學、計算機與生命科學交叉研究"青年學者論壇
Other conference paper
iSeeRNA: identification of long intergenic non-coding RNA transcripts from transcriptome sequencing data
Sun K, Chen XN, Jiang PY, Song XF, Wang HT, Sun H ( 2013 )
BMC GENOMICS
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1186/1471-2164-14-S2-S7
Linc-YY1, A Novel Functional Long Non-coding RNA in Myogenic Differentiation and Muscle Regeneration
ZHOU Liang, SUN, Kun, LU Leina, CHEN, Xiaona, WANG Lijun, TANG Ling Yin, WANG Chi Chiu, SUN Hao, WANG Huating ( 2013 )
6th Guangzhou International Conference on Stem Cell and Regenerative Medicine and the 2nd Annual Conference of Chinese Society for Regenerative Cell Biology
Refereed conference paper presented and published in conference proceedings
miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes
Zhong X, Chung ACK, Chen HY, Dong Y, Meng XM, Li R, Yang W, Hou FF, Lan HY ( 2013 )
DIABETOLOGIA
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1007/s00125-012-2804-x
Molecular Mechanisms Regulating the Synergism between IL-32g and NOD Ligands for the Induction of Adhesion Molecules, Cytokines and Chemokines of Eosinophils in Allergic Inflammation
DONG, Jie 董杰, WONG Chun Kwok, LAM Wai Kei Christopher ( 2013 )
The 20th Anniversary & 2013 Annual General Meeting and Scientific Meeting of The Hong Kong Society for Immunology
Other conference paper
Molecular Mechanisms Regulating the Synergism between IL-32g and NOD Ligands for the Induction of Adhesion Molecules, Cytokines and Chemokines of Eosinophils in Allergic Inflammation
DONG, Jie 董杰, WONG Chun Kwok, LAM Wai Kei Christopher ( 2013 )
The 18th Annual General Meeting and Scientific Meeting of The Hong Kong Society of Flow Cytometry
Other conference paper
Muramyl dipeptide mediated activation of human bronchial epithelial cells interacting with basophils: a novel mechanism of airway inflammation
Qiu HN, Wong CK, Chu IMT, Hu S, Lam CWK ( 2013 )
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1111/cei.12031
NOD-like receptors mediated activation of eosinophils interacting with bronchial epithelial cells: a link between innate immunity and allergic asthma
Wong CK, Hu SQ, Leung KML, Dong J, He L, Chu YJ, Chu IMT, Qiu HN, Liu KYP, Lam CWK ( 2013 )
CELLULAR & MOLECULAR IMMUNOLOGY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1038/cmi.2012.77
Noninvasive detection of cancer-associated genomewide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing
Allen Chan K.C., Jiang P., Chan C.W.M., Sun K., Wong J., Hui E.P., Chan S.L., Chan W.C., Hui D.S.C., Ng S.S.M., Chan H.L.Y., Wong C.S.C., Ma B.B.Y., Chan A.T.C., Lai P.B.S., Sun H., Chiu R.W.K., Dennis Lo Y.M. ( 2013 )
Proceedings of the National Academy of Sciences of the United States of America
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1073/pnas.1313995110
Non-invasive Detection of Somatic Mitochondrial Mutations in Plasma by Massively Parallel Sequencing in Cancer Patients
CHAN Wai Man, JIANG Peiyong, WONG, IN CHUN, CHAN Kwan Chee, ZHENG Wenli, LIAO Jiawei Gary, SUN Hao, WONG John, SIU Shing Shun Nelson, CHAN Wing Cheong, CHAN Lam Stephen, CHAN Anthony Tak Cheung, LAI Bo San Paul, CHIU Wai Kwun Rossa, LO Yuk Ming Dennis ( 2013 )
Joint Conference of HGM 2013 and 21st International Congress of Genetics: Genetics & Genomics of Global Health and Sustainability
Refereed conference paper presented and published in conference proceedings
Noninvasive Prenatal Determination of Twin Zygosity by Maternal Plasma DNA Analysis
Qu JZZ, Leung TY, Jiang PY, Liao GJW, Cheng YKY, Sun H, Chiu RWK, Chan KCA, Lo YMD ( 2013 )
CLINICAL CHEMISTRY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1373/clinchem.2012.194068
Noninvasive Prenatal Methylomic Analysis by Genomewide Bisulfite Sequencing of Maternal Plasma DNA
Lun FMF, Chiu RWK, Sun K, Leung TY, Jiang PY, Chan KCA, Sun H, Lo YMD ( 2013 )
CLINICAL CHEMISTRY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1373/clinchem.2013.212274
Noninvasive twin zygosity assessment and aneuploidy detection by maternal plasma DNA sequencing
Leung T.Y., Qu J.Z.Z., Liao G.J.W., Jiang P., Cheng Y.K.Y., Chan K.C.A., Chiu R.W.K., Lo Y.M.D. ( 2013 )
Prenatal Diagnosis
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1002/pd.4132
Noninvasive twin zygosity assessment and aneuploidy detection by maternal plasma DNA sequencing
Leung TY, Qu JZZ, Liao GJW, Jiang PY, Cheng YKY, Chan KCA, Chiu RWK, Lo YMD ( 2013 )
PRENATAL DIAGNOSIS
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1002/pd.4132
Pattern Recognition Receptors of Eosinophils and Basophils: implications in Allergic inflammation
WONG Chun Kwok, QIU, Huaina, HU, SHUIQING, LEUNG, Ming Lam, LAM Wai Kei Christopher ( 2013 )
13th Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress
Invited conference paper presented and published in conference proceedings
Smad7 suppresses renal fibrosis via altering expression of TGF-β/Smad3-regulated microRNAs
Chung A.C.K., Dong Y., Yang W., Zhong X., Li R., Lan H.Y. ( 2013 )
Molecular Therapy
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1038/mt.2012.251
Suppression of Azin1 by miR-433 enhances renal fibrosis
LI Rong, CHUNG Chi Kong Arthur, DONG Yuan, LAN Hui Yao ( 2013 )
ISN World Congress of Nephrology 2013
Refereed conference paper presented and published in conference proceedings
Suppression of malignancy by Smad3 in mouse embryonic stem cell formed teratoma
Li P, Chen Y, Meng XM, Kwok KY, Huang XR, Choy KW, Wang CC, Lan HY, Yuan P ( 2013 )
STEM CELL REVIEWS AND REPORTS
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1007/s12015-013-9452-5
The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-beta/Smad3-Azin1 pathway
Li R, Chung ACK, Dong Y, Yang WQ, Zhong X, Lan HY ( 2013 )
KIDNEY INTERNATIONAL
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1038/ki.2013.272
YY1TargetDB: an integral information resource for Yin Yang 1 target loci
Guo AM, Sun K, Su XX, Wang HT, Sun H ( 2013 )
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1093/database/bat007
YY1TargetDB: An integral information resource for Yin Yang 1 target loci
Guo A.M., Sun K., Su X., Wang H., Sun H. ( 2013 )
Database
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1093/database/bat007
Zinc-finger protein 545 is a novel tumour suppressor that acts by inhibiting ribosomal RNA transcription in gastric cancer
Wang SY, Cheng YD, Du W, Lu LN, Zhou L, Wang HT, Kang W, Li XX, Tao Q, Sung JJY, Yu J ( 2013 )
GUT
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1136/gutjnl-2011-301776

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研究成果 (45)

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