研究成果 (111)

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ZNF312 AT 3p14.2 is a novel tumor suppressor gene frequently inactivated in nasopharyngeal carcinoma, 13-14 Nov 2010
SHU Xingsheng, FAN Yichao, YING JIANMING, NG Ka Man, CHENG Y, CHAN Anthony Tak Cheung, TAO Qian ( 2010 )
The 15th Annual Scientific Symposium of Hong Kong Cancer Institute - 5th Sino-US Conference: Personalized Medicine in Cancer Therapy
Invited conference paper presented and published in conference proceedings
WNT5A antagonizes WNT/beta-catenin signaling and is frequently silenced by promoter CpG methylation in esophageal squamous cell carcinoma
Li JS, Ying JM, Fan YC, Wu LT, Ying Y, Chan ATC, Srivastava G, Tao QA ( 2010 )
CANCER BIOLOGY & THERAPY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.4161/cbt.10.6.12609
Towards Personalized Therapy in Breast cancer
YEO Winnie ( 2010 )
Annual Scientific Meeting in Novel Therapeutic in Medical Practice
Invited conference paper presented and published in conference proceedings
Thromboxane synthase suppression induces lung cancer cell apoptosis via inhibiting NF-kappa B
Leung KC, Li MY, Leung BCS, Hsin MKY, Mok TSK, Underwood MJ, Chen GG ( 2010 )
EXPERIMENTAL CELL RESEARCH
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.yexcr.2010.07.003
The use of serum hepatitis B viral DNA in prognostication of liver cancers undergoing non-surgical therapy
CHAN Lam Stephen, MO Kwok Fai, WONG Wai Sun Vincent, CHAN Lik Yuen Henry, CHAN Kay Sheung Paul, WONG K, YEO Winnie ( 2010 )
Health Research Symposium 2010: Improving Health and Recognising Excellence
Other conference paper
The Tumor Suppressor UCHL1 Forms a Complex with p53/MDM2/ARF to Promote p53 Signaling and Is Frequently Silenced in Nasopharyngeal Carcinoma
Li LL, Tao Q, Jin HC, van Hasselt A, Poon FF, Wang X, Zeng MS, Jia WH, Zeng YX, Chan ATC, Cao Y ( 2010 )
CLINICAL CANCER RESEARCH
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1158/1078-0432.CCR-09-3178
The significance of serum interleukin - 10 on the outcome of unresectable Hepatocellular Carcinoma (HCC)
CHAN Lam Stephen, WONG Sze Chuen Cesar, MO Kwok Fai, HUI Pun Edwin, MA Buig Yue Brigette, CHAN Anthony Tak Cheung, MOK Shu Kam Tony, YEO Winnie ( 2010 )
5th Sino-US Conference Personalized Medicine in Cancer Therapy in conjunction with the 15th Annual Scientific Symposium of the Hong Kong Cancer Institute
Other conference paper
The Role of Thromboxane A2 in the Proliferation of Lung Cancer Cells Induced by Smoking Carcinogen 4-methylnitrosamino-1-3-pyridyl-1-butanone
Chen GG, Huang R, Li M, Hsin MKY, Mok TSK, Underwood MJ ( 2010 )
JOURNAL OF THORACIC ONCOLOGY
Other conference paper
The Role Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Management of Advanced Non-Small Cell Lung Cancer
MOK Shu Kam Tony ( 2010 )
8th Annual Meeting of Japanese Society of Medical Oncology
Invited conference paper presented and published in conference proceedings
The Relationship of White Matter Lesion and Contract Enhanced Lesion Development Course in Radiation Induced Brain Injury: an MRI Based Study
HUANG H, DENG min, LEUNG Sing Fai, CHAN Yl, YEUNG Ka Wai Daivd, CHAN Hc, AHUJA Anil Tejbhan, WANG Yixiang ( 2010 )
Joint Scientific Meeting of ISMRM-ESMRMB
Other conference paper
Therapeutics in Hepatocellular Carcinoma
YEO Winnie ( 2010 )
5th Sino-US Conference Personalized Medicine in Cancer Therapy in conjunction with the 15th Annual Scientific Symposium of the Hong Kong Cancer Institute
Invited conference paper presented and published in conference proceedings
The preparation of bi-functional organophosphine oxides as potential antitumor agents
Lam KH, Chui CH, Gambari R, Wong RSM, Cheng GYM, Lau FY, Lai PBS, Tong SW, Chan KW, Wong WY, Chan ASC, Tang JCO ( 2010 )
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.ejmech.2010.08.038
The preclinical activity of the histone deacetylase inhibitor PXD101 (belinostat) in hepatocellular carcinoma cell lines
Ma BBY, Sung F, Tao Q, Poon FF, Lui VW, Yeo W, Chan SL, Chan ATC ( 2010 )
INVESTIGATIONAL NEW DRUGS
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1007/s10637-009-9219-7
The KRAB-Containing Zinc Finger Protein ZNF545 Is A Functional Tumor Suppressor Exerting Proapoptotic and Anti-proliferation Abilities with Frequent Epigenetic Inactivation in Multiple Carcinomas
CHENG Yingduan, LIANG Pei, GENG Hua, CHENG Suk Hang, NG Heung Ling Margaret, CHAN Anthony Tak Cheung, TAO Qian ( 2010 )
AACR Annual meeting 2010
Refereed conference paper presented and published in conference proceedings
數位物件識別號 (DOI): http://dx.doi.org/10.1158/1538-7445.AM10-197
The impact of antiviral therapy on the outcome of hepatitis B viral (HBV)-related hepatocellular carcinoma (HCC) detected in surveillance prorgram
Wong VW, Mo F, Liem GS, Mok T, Chan AT, Chan HL, Yeo W, Chan SL ( 2010 )
Journal of Clinical Oncology
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1200/jco.2010.28.15_suppl.4028
The Impact of Antiviral Therapy on the Outcome of Hepatitis B Viral (HBV)-related Hepatocellular Carcinoma (HCC) Detected in Surveillance Program
WONG Wai Sun Vincent, MO Kwok Fai, LIEM Giok Siong, MOK Shu Kam Tony, CHAN Anthony Tak Cheung, CHAN H.L.Y., YEO Winnie, CHAN Lam Stephen ( 2010 )
ASCO Annual Meeting 2010
Refereed conference paper presented and published in conference proceedings
The expression of CYP1B1 predicts neutropenia after adjuvant chemotherapy in breast cancer patients
YEO Winnie, SUEN Joyce, CHAN Tung Ching, MO Kwok Fai, NG Wing Yam, PANG Elizabeth Summing, HO W Ming, LIAO Chen Di, FU B Y, TANG Leung Sang Nelson ( 2010 )
7th European Breast Cancer Conference (EBCC7)
Refereed conference paper presented and published in conference proceedings
The Clinical role of suppression of Hepatitis B viral activity in patients with established Hepatocellular Carcinoma
CHAN Lam Stephen, MO Kwok Fai, WONG Wai Sun Vincent, CHAN Lik Yuen Henry, CHAN Kay Sheung Paul, WONG Kenneth, MA Buig Yue Brigette, CHAN Anthony Tak Cheung, MOK Shu Kam Tony, YEO Winnie ( 2010 )
5th Sino-US Conference Personalized Medicine in Cancer Therapy in conjunction with the 15th Annual Scientific Symposium of the Hong Kong Cancer Institute
Other conference paper
The activity of mTOR inhibitor RAD001 (everolimus) in nasopharyngeal carcinoma and cisplatin-resistant cell lines
Ma BBY, Lui VWY, Hui EP, Lau CPY, Ho K, Ng MHL, Cheng SH, Tsao SW, Chan ATC ( 2010 )
INVESTIGATIONAL NEW DRUGS
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1007/s10637-009-9269-x
T-Cell Response to Human Papillomavirus Type 58 L1, E6, and E7 Peptides in Women with Cleared Infection, Cervical Intraepithelial Neoplasia, or Invasive Cancer
Chan PKS, Liu SJ, Cheung TH, Yeo W, Ngai SM, Cheung JLK, Chong P, Man S ( 2010 )
CLINICAL AND VACCINE IMMUNOLOGY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1128/CVI.00105-10
Systemic Therapy for Advanced Gastric Cancer
YEO Winnie ( 2010 )
The First Oncology Forum of Hong Kong
Invited conference paper presented and published in conference proceedings
Systemic therapy for advanced gastric cancer
Yeo W. ( 2010 )
Journal of the Hong Kong College of Radiologists
Publication in refereed journal
Synthesis, characterization and preliminary analysis of in vivo biological activity of chitosan/celecoxib microcapsules
Cheng SY, Yuen CWM, Lam PL, Gambari R, Wong RSM, Cheng GYM, Lai PBS, Tong SW, Chan KW, Lau FY, Kok SHL, Lam KH, Chui CH ( 2010 )
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.bmcl.2010.05.054
Risk of second primary malignancies following nasopharyngeal carcinoma in Hong Kong
Goggins W.B., Yu I.T.S., Tse L.A., Leung S.F., Tung S.Y., Yu K.S. ( 2010 )
Cancer Causes and Control
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1007/s10552-010-9574-x
Reverse phase protein array identifies novel anti-invasion mechanisms of YC-1
Hong B, Lui VWY, Hui EP, Lu YL, Leung HSY, Wong EYL, Cheng SH, Ng MHL, Mills GB, Chan ATC ( 2010 )
BIOCHEMICAL PHARMACOLOGY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.bcp.2009.10.021
RANDOMIZED TRIALS IN PATIENTS WITH EGFR MUTATIONS
Mok T ( 2010 )
JOURNAL OF THORACIC ONCOLOGY
Other conference paper
Randomized, Open-Label Phase II Study of Motesanib or Bevacizumab in Combination with Paclitaxel and Carboplatin (P/C) for Advanced Nonsquamous Non-Small Cell Lung Cancer (NSCLC)
BLUMENSCHEIN R. G., KABBINAVAR F. F., MENON H., MOK Shu Kam Tony, STEPHENSON J., BECK T. J., LAKSHMAIAH K., KRACHT K., SIKORSKI S. R., SCHWARTZBERG S. L. ( 2010 )
ASCO Annual Meeting 2010
Refereed conference paper presented and published in conference proceedings
Randomized, Open Label, Phase III Trial of Figitumumab in Combination With Paclitaxel and Carboplatin Versus Paclitaxel and Carboplatin in Patients With Non-Small Cell Lung Cancer (NSCLC)
MOK Shu Kam Tony, JASSEM J., LANGER J. C., KARP D. D., BENNER J. R., GREEN J. S., PARK K., NOVELLO S., STRAUSZ J., GUALBERTO A. ( 2010 )
ASCO Annual Meeting 2010
Refereed conference paper presented and published in conference proceedings
Quality of Life (QOL) in a Randomized Phase III First-Line Study of Gefitinib (G) vs Carboplatin/Paclitaxel (CP) in Clinically Selected Asian Patients (PTS) with Advanced NSCLC (IPASS)
THONGPRASERT S, DUFFIELD E, WU Y, YANG C, SAIJO N, CHU D.t., CHAN V, MOK Shu Kam Tony, MAGILL P, FUKUOKA M ( 2010 )
2nd European Lung Cancer Conference
Refereed conference paper presented and published in conference proceedings
Quality of Life Assessment with Eortic-HCC18 as a Predictor for Survival of Patients with Hepatocellular Carcinoma
YEO Winnie, LI Leung, CHAN Lam Stephen, KOH J., HUI Pun Edwin, MA Buig Yue Brigette, LAM Kwok Chi, HO Ming Wing, POON Annette, MOK Shu Kam Tony, CHAN Anthony Tak Cheung, MO Kwok Fai ( 2010 )
12th World Congress on Gastrointestinal Cancer
Invited conference paper presented and published in conference proceedings
QUALITY OF LIFE ASSESSMENT WITH COMBINED EORTC QLQ-C30 AND EORTC-HCC18 AS A PROGNOSTIC FACTOR FOR PATIENTS WITH HEPATOCELLULAR CARCINOMA: A PROSPECTIVE STUDY
LI Leung, CHAN Lam Stephen, MO Kwok Fai, KOH J., HUI Pun Edwin, MA Buig Yue Brigette, MOK Shu Kam Tony, CHAN Anthony Tak Cheung, YEO Winnie ( 2010 )
35th ESMO Congress
Invited conference paper presented and published in conference proceedings
QOL Assessment in patients with liver cancer. (Abt#S3B.1)
YEO Winnie ( 2010 )
2010 Asian Chinese Quality of Life Conference, "Quality of Life - Outcome for All"
Invited conference paper presented and published in conference proceedings
Preoperative Transarterial Chemoembolization for Resectable Large Hepatocellular Carcinoma Reply
Lau WY, Lai ECH, Wu MC, Zhou WP ( 2010 )
ANNALS OF SURGERY
Other outputs
數位物件識別號 (DOI): http://dx.doi.org/10.1097/SLA.0b013e3181cb8940
Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC
Turke AB, Zejnullahu K, Wu YL, Song Y, Dias-Santagata D, Lifshits E, Toschi L, Rogers A, Mok T, Sequist L, Lindeman NI, Murphy C, Akhavanfard S, Yeap BY, Xiao Y, Capelletti M, Iafrate AJ, Lee C, Christensen JG, Engelman JA, Janne PA ( 2010 )
CANCER CELL
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.ccr.2009.11.022
Preclinical evaluation of the PI3K inhibitor BEZ235 in nasopharyngeal carcinoma cell lines
MA Buig Yue Brigette, LUI V, HO K, LAU P Y, NG M, CHENG S H, TSANG C M, TSAO S W, SHI M, HUI Pun Edwin, CHAN Anthony Tak Cheung ( 2010 )
Proc American Association of Cancer Research meeting, 2010
Invited conference paper presented and published in conference proceedings
Preclinical evaluation of the P13K inhibitor BEZ235 in nasopharyngeal carcinoma
MA Buig Yue Brigette, LUI Wai Yan Vivian, HO Kakiu, LAU Pik Yuk Cecilia, NG Heung Ling Margaret, CHENG Suk Hang, TSANG Chi Man, TSAO Sai Wah, SHI Michael, HUI Edwin P, CHAN Anthony Tak Cheung ( 2010 )
AACR Annual meeting 2010
Other conference paper
Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response
Ma BBY, Lui VWY, Poon FF, Wong SCC, To KF, Wong E, Chen HL, Lo KW, Tao Q, Chan ATC ( 2010 )
INVESTIGATIONAL NEW DRUGS
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1007/s10637-009-9316-7
PPAR gamma Activation Extinguishes Smoking Carcinogen by Inhibiting NNK-Mediated Proliferation
Li MY, Hsin MKY, Yip J, Mok TSK, Underwood MJ, Chen GG ( 2010 )
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1165/rcmb.2008-0463OC
Population-based differences in treatment outcome following anticancer drug therapies
Ma BBY, Hui EP, Mok TSK ( 2010 )
LANCET ONCOLOGY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/S1470-2045(09)70160-3
PLCD1 is a functional tumor suppressor inducing G(2)/M arrest and frequently methylated in breast cancer
Xiang TX, Li LL, Fan YC, Jiang YY, Ying Y, Putti TC, Tao QA, Ren GS ( 2010 )
CANCER BIOLOGY & THERAPY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.4161/cbt.10.5.12726
Phospho-HSP27 as a novel target of celecoxib in nasopharyngeal carcinoma cell lines
CHAN C M L, MO Kwok Fai, MA Buig Yue Brigette, LAM M, AU T, CHAN Anthony Tak Cheung, HUI Pun Edwin, WONG S C ( 2010 )
ASCO-NCI-EORTC Molecular Markers Meeting
Invited conference paper presented and published in conference proceedings
Phase I pharmacokinetics and metabolic pathway of belinostat in patients with hepatocellular carcinoma. Abstr No. 2585
WANG L, GOH B C, LWIN T W, LEE H, CHAN Lam Stephen, LIM R S, CHAN Anthony Tak Cheung, YEO Winnie ( 2010 )
American Society Clinical Oncology (ASCO) annual meeting 2010
Refereed conference paper presented and published in conference proceedings
數位物件識別號 (DOI): http://dx.doi.org/10.1200/jco.2010.28.15_suppl.2585
Personalized medicine for non-small-cell lung cancer
Mok TS, Zhou Q, Leung L, Loong HH ( 2010 )
EXPERT REVIEW OF ANTICANCER THERAPY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1586/ERA.10.76
Personalized Management of Lung Cancer: EGFR Mutation and Beyond
MOK Shu Kam Tony ( 2010 )
35th ESMO Congress
Refereed conference paper presented and published in conference proceedings
Personalized cancer therapy coming of age: clinical highlights in 2009 and future directions
Ma BBY, Loong H ( 2010 )
PERSONALIZED MEDICINE
Publication in policy or professional journal
數位物件識別號 (DOI): http://dx.doi.org/10.2217/PME.10.11
PARP inhibition in BRCA-mutated breast and ovarian cancers
Chan SL, Mok T ( 2010 )
LANCET
Publication in policy or professional journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/S0140-6736(10)61119-1
Osteoradionecrosis of the upper cervical spine: MR imaging following radiotherapy for nasopharyngeal carcinoma
King AD, Griffith JF, Abrigo JM, Leung SF, Yau FK, Tse GMK, Ahuja AT ( 2010 )
EUROPEAN JOURNAL OF RADIOLOGY
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1016/j.ejrad.2008.12.016
Oncology and Palliative Care - QOL assessment in patients with liver cancer
YEO Winnie ( 2010 )
2010 Asian Quality of Life Conference- Quality of Life, the Outcome for All
Invited conference paper presented and published in conference proceedings
Novel Use of Silymarin as Delayed Therapy for Acetaminophen-Induced Acute Hepatic Injury
Hau DKP, Wong RSM, Cheng GYM, Wong WY, Tong SW, Chan KW, Leung AKM, Zhu GY, Lai PBS, Lau FY, Chui CH, Gambari R, Fong DWF ( 2010 )
FORSCHENDE KOMPLEMENTARMEDIZIN
Publication in refereed journal
數位物件識別號 (DOI): http://dx.doi.org/10.1159/000319317
Novel Therapeutic Potential in Targeting the Microtubules by Nanoparticle Albumin-bound Paclitaxel in Hepatocellular Carcinoma
ZHOU, Qian, CHING K K, LEUNG K C, SZETO Y Y, HO S M, HOLMES C, YUAN Y F, LAI Bo San Paul, YEO Winnie, WONG Nathalie ( 2010 )
101st Annual Meeting of the American Association for Cancer Research
Refereed conference paper presented and published in conference proceedings

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研究成果 (111)

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