Research Outputs (1632)

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Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19
Zuo T, Liu Q, Zhang F, Lui GC, Tso EY, Yeoh YK, Chen Z, Boon SS, Chan FK, Chan PK, Ng SC ( 2021 )
Gut
Publication in refereed journal
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276.full.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1136/gutjnl-2020-322294
Population-level configurations of gut mycobiome across six ethnicities in urban and rural China
Sun Y, Zuo T, Cheung CP, Gu W, Wan Y, Zhang F, Chen N, Zhan H, Yeoh YK, Niu J, Du Y, Zhang F, Wen Y, Yu J, Sung JJ, Chan PK, Chan FK, Wang K, Ng SC, Miao Y ( 2021 )
Gastroenterology
Publication in refereed journal
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1-s2.0-S0016508520351623-main.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1053/j.gastro.2020.09.014
Acceptability and Feasibility of HPV Self-Sampling as an Alternative Primary Cervical Cancer Screening in Under-Screened Population Groups: A Cross-Sectional Study
Wong Eliza Lai-Yi, Cheung Annie Wai-Ling, Wong Amy Yuen-Kwan, Chan Paul Kay-Sheung ( 2020 )
International Journal of Environmental Research and Public Health
Publication in refereed journal
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ijerph-17-06245-v2.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.3390/ijerph17176245
Adherence to Treatment Guideline Improves Patient Outcomes in a Prospective Cohort of Adults Hospitalized for Community-Acquired Pneumonia
Lui Grace , To W K Heather , Lee Nelson , Chan W Y Renee , Li Timothy , Wong K Y Rity , Hui C S David , Ip Margaret ( 2020 )
Publication in refereed journal
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ofaa146.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1093/OFID/OFAA146
Alterations in Fecal Fungal Microbiome of Patients With COVID-19 During Time of Hospitalization until Discharge
Zuo T, Zhan H, Zhang F, Liu Q, Tso EYK, Lui GCY, Chen N, Li A, Lu W, Chan FKL, Chan PKS, Ng SC ( 2020 )
Gastroenterology
Publication in refereed journal
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Alterations in Fecal Fungal Microbiome of Patients With COVID-19 During Time of Hospitalization until Discharge.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1053/j.gastro.2020.06.048
Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization
Zuo T, Zhang F, Lui GCY, Yeoh YK, Li AYL, Zhan H, Wan Y, Chung A, Cheung CP, Chen N, Lai CKC, Chen Z, Tso EYK, Fung KSC, Chan V, Ling L, Joynt G, Hui DSC, Chan FKL, Chan PKS, Ng SC ( 2020 )
Gastroenterology
Publication in refereed journal
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Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1053/j.gastro.2020.05.048
A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa
Lo SW, Gladstone RA, van Tonder AJ, Du Plessis M, Cornick JE, Hawkins PA, Madhi SA, Nzenze SA, Kandasamy R, Ravikumar KL, Elmdaghri N, Kwambana-Adams B, Almeida SCG, Skoczynska A, Egorova E, Titov L, Saha SK, Paragi M, Everett DB, Antonio M, Klugman KP, Li Y, Metcalf BJ, Beall B, McGee L, Breiman RF, Bentley SD, von Gottberg A, Global Pneumococcal Sequencing Consortium ( 2020 )
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1093/jac/dkz477
Anti-inflammatory mechanisms of the novel cytokine interleukin-38 in allergic asthma
Xiaoyu Sun, Tianheng Hou, Edwin Cheung, Tiffany Nga-Teng Iu, Victor Wai-Hou Tam, Ida Miu-Ting Chu, Miranda Sin-Man Tsang, Paul Kay-Sheung Chan, Christopher Wai-Kei Lam, Chun-Kwok Wong ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1038/s41423-019-0300-7
A polysaccharide extract from the medicinal plant Maidong inhibits the IKK-NF-κB pathway and IL-1β-induced islet inflammation and increases insulin secretion
Dandan Mao, Xiao Yu Tian, Di Mao, Sze Wan Hung, Chi Chiu Wang, Clara Bik San Lau, Heung Man Lee, Chun Kwok Wong, Elaine Chow, Xing Ming, Huanyi Cao, Ronald C. Ma, Paul K. S. Chan, Alice P. S. Kong, Joshua J. X. Li, Guy A. Rutter, Wing Hung Tam, Juliana C. N. Chan ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1074/jbc.RA120.014357
A Randomized Controlled Trial of Different Young Child Formulas on Upper Respiratory and Gastrointestinal Tract Infections in Chinese Toddlers
Ting Fan Leung, Laurien H. Ulfman, Marc Ka Chun Chong, Kam Lun Hon, Ilse M. S. L. Khouw, Paul Kay Sheung Chan, Dianne J. Delsing, Guus A. M. Kortman, Ingeborg M. J. Bovee-Oudenhoven ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1111/pai.13276
A simple, rapid typing method for Streptococcus agalactiae based on ribosomal subunit proteins by MALDI-TOF MS
Rothen J, Sapugahawatte DN, Li C, Lo N, Vogel G, Foucault F, Pflüger V, Pothier JF, Blom J, Daubenberger C, Ip M ( 2020 )
Scientific reports
Publication in refereed journal
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s41598-020-65707-5.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1038/s41598-020-65707-5
Association between meteorological variations and activities of influenza A and B across different climate zones: A multi-region modelling analysis across the globe
Ka Chun Chong, Tsz Cheung Lee, Seweryn Bialasiewicz, Jian Chen, David W. Smith, Wisely S.C. Choy, Mel Krajden, Hamid Jalal, Lance Jennings, Burmaa Alexander, Hong Kai Lee, Pieter Fraaij, Avram Levy, Apple C.M. Yeung, Sarah Tozer, Steven Y.F. Lau, Katherine M. Jia, Julian W.T. Tang, David S.C. Hui, Paul K.S. Chan ( 2020 )
Journal of Infection
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jinf.2019.09.013
Association of HPV35 with cervical carcinogenesis among women of African ancestry: Evidence of viral-host interaction with implications for disease intervention
Pinheiro M, Gage JC, Clifford GM, Demarco M, Cheung LC, Chen ZG, Yeager M, Cullen M, Boland JF, Chen XJ, Raine-Bennett T, Steinberg M, Bass S, Befano B, Xiao YZ, Tenet V, Walker J, Zuna R, Poitras NE, Gold MA, Dunn T, Yu K, Zhu B, Burdett L, Turan S, Lorey T, Castle PE, Wentzensen N, Burk RD, Schiffman M, Mirabello L ( 2020 )
INTERNATIONAL JOURNAL OF CANCER
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1002/ijc.33033
A systematic review on current osteosynthesis-associated infection animal fracture models
Ronald M.Y. Wong, Tsz-kiu Li, Jie Li, Wing-Tung Ho, Simon K.-H. Chow, Sharon S.Y. Leung, Wing-Hoi Cheung, Margaret Ip ( 2020 )
Journal of orthopaedic translation
Publication in refereed journal
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1-s2.0-S2214031X20300322-main.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jot.2020.03.002
Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancer
Xia XX, Wu WKK, Wong SH, Liu D, Kwong TNY, Nakatsu G, Yan PS, Chuang YM, Chan MWY, Coker O, Chen ZG, Yeoh YK, Zhao LY, Wang XS, Cheng WY, Chan MTV, Chan PKS, Sung JJY, Wang MHT, Yu J ( 2020 )
Publication in refereed journal
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s40168-020-00847-4.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1186/s40168-020-00847-4
Benzyl and Benzoyl Benzoic Acid Inhibitors of Bacterial RNA Polymerase-Sigma Factor Interaction
Ye J, Chu AJ, Lin L, Chan ST, Harper R, Xiao M, Artsimovitch I, Zuo Z, Ma C, Yang X ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.ejmech.2020.112671
Biological characteristics associated with virulence in Clostridioides difficile ribotype 002 in Hong Kong
Ka Yi Kong , Thomas N Y Kwong , Hung Chan , Kristine Wong , Samuel S Y Wong , Anu P Chaparala , Raphael C Y Chan , Lin Zhang , Joseph J Y Sung , Jun Yu , Peter M Hawkey , Margaret Ip , William K K Wu , Sunny H Wong ( 2020 )
Publication in refereed journal
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Biological characteristics associated with virulence in Clostridioides difficile ribotype 002 in Hong Kong.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1080/22221751.2020.1739564
Contemporary approaches and future perspectives of antibacterial photodynamic therapy (aPDT) against methicillin-resistant Staphylococcus aureus (MRSA): A systematic review
Priyanga Dharmaratne, Dulmini Nanayakkara Sapugahawatte, Baiyan Wang, Chung Lap Chan, Kit-Man Lau, Clara Lau, Kwok Pui Fung, Dennis KP. Ng, Margaret IP ( 2020 )
European Journal of Medicinal Chemistry
Publication in refereed journal
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1-s2.0-S0223523420303111-main.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.ejmech.2020.112341
Cost-effectiveness analysis of fecal microbiota transplantation for recurrent Clostridium difficile infection in patients with inflammatory bowel disease
Joyce HS You, Xinchan Jiang, Wally H Lee, Paul K S Chan, Siew C Ng ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1111/jgh.15002
Detection of SARS-CoV-2 RNA in fecal specimens of patients with confirmed COVID-19: a meta-analysis
Wong MCS, Huang JJ, Lai C, Ng R, Chan FKL, Chan PKS ( 2020 )
The Journal of infection
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jinf.2020.06.012
Development of thermosensitive hydrogel containing methylene blue for topical antimicrobial photodynamic therapy
Leung B, Dharmaratne P, Yan W, Chan BCL, Lau CBS, Fung KP, Ip M, Leung SSY ( 2020 )
Journal of photochemistry and photobiology. B, Biology
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jphotobiol.2020.111776
Discovery of Antibacterials That Inhibit Bacterial RNA Polymerase Interactions with Sigma Factors
Ye J, Chu AJ, Harper R, Chan ST, Shek TL, Zhang Y, Ip M, Sambir M, Artsimovitch I, Zuo Z, Yang X, Ma C ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1021/acs.jmedchem.0c00520
Epidemiological characteristics of the first 100 cases of coronavirus disease 2019 (COVID-19) in Hong Kong Special Administrative Region, China, a city with a stringent containment policy
Lai CKC, Ng RWY, Wong MCS, Chong KC, Yeoh YK, Chen ZG, Chan PKS ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1093/ije/dyaa106
Facilitators and barriers to completing recommended doses of pneumococcal vaccination among community-living individuals aged ≥65 years in Hong Kong – a population-based study
Wang ZX, Fang Y, Ip M, Lau M, Lau JTF ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1080/21645515.2020.1776545
Fecal microbial DNA markers serve for screening colorectal neoplasm in asymptomatic subjects
Jessie Qiaoyi Liang, Sunny H Wong, Chun Ho Szeto, Eagle SH Chu, Harry C Lau, Yingxuan Chen, Jingyuan Fang, Jun Yu, Joseph JY Sung ( 2020 )
Publication in refereed journal
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jgh.15171.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1111/jgh.15171
Genome Sequence of a Human Norovirus GII.4 Hong Kong[P31] Variant in Hong Kong, China
Tse EHY, Zhang L, Lau S, Chan MC ( 2020 )
Microbiology Resource Announcements
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1128/MRA.01391-19
Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia
Kelly L. Wyres, To N. T. Nguyen, Margaret M. C. Lam, Louise M. Judd, Nguyen van Vinh Chau, David A. B. Dance, Margaret Ip, Abhilasha Karkey, Clare L. Ling, Thyl Miliya, Paul N. Newton, Nguyen Phu Huong Lan, Amphone Sengduangphachanh, Paul Turner, Balaji Veeraraghavan, Phat Voong Vinh, Manivanh Vongsouvath, Nicholas R. Thomson, Stephen Baker, Kathryn E. Holt ( 2020 )
Genome medicine
Publication in refereed journal
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s13073-019-0706-y.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1186/s13073-019-0706-y
Human-Gut-DNA Virome Variations across Geography, Ethnicity, and Urbanization
Zuo T, Sun Y, Wan Y, Yeoh YK, Zhang F, Cheung CP, Chen N, Luo J, Wang W, Sung JJY, Chan PKS, Wang K, Chan FKL, Miao Y, Ng SC ( 2020 )
Cell host & microbe
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.chom.2020.08.005
Human Papillomavirus 58 E7 T20I/G63S Variant Isolated from an East Asian Population Possesses High Oncogenicity
Siaw Shi Boon, Chichao Xia, Jin Yan Lim, Zigui Chen, Priscilla T. Y. Law, Apple C. M. Yeung, Miranda Thomas, Lawrence Banks, Paul K. S. Chan ( 2020 )
Publication in refereed journal
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Journal of Virology-2020-Boon-e00090-20.full.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1128/JVI.00090-20
Long-Term Outcomes Following Infant Group B Streptococcal Sepsis and Meningitis in Hong Kong
Reema Subramanian, Hugh Simon Hung San Lam, Carmen Li, Ting Fan Leung, Margaret IP ( 2020 )
Publication in refereed journal
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long-term-outcomes-following-infant-group-B-streptococcal-sepsis-and-meningitis-in-hong-kong.pdf
Metagenomic Analysis of Human Fecal Virome Showed Geography and Population-Specific Signatures in Obesity
Keli Yang, Junkun Niu, Zhilu XU, Yang Sun, Tao Zuo, Whitney Tang, Jingwan Zhang, Qin Liu, Enders K. Ng, Simon K. Wong, Paul K. Chan, Francis K. Chan, Yinglei Miao, Siew C. Ng ( 2020 )
Refereed conference paper presented and published in conference proceedings
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/S0016-5085(20)33150-4
Monosubstituted tricationic Zn(II) phthalocyanine enhances antimicrobial photodynamic inactivation (aPDI) of methicillin-resistant Staphylococcus aureus (MRSA) and cytotoxicity evaluation for topical applications: in vitro and in vivo study
Priyanga Dharmaratne, Baiyan Wang, Roy C H Wong, Ben C L Chan, Kit-Man Lau, Mei-Rong Ke, Clara B S Lau, Dennis K P Ng, Kwok-Pui Fung, Margaret Ip ( 2020 )
Publication in refereed journal
View Full-text in CUHK:
(214) EMI-20-1628.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1080/22221751.2020.1790305
Multidrug-Resistant Streptococcus agalactiae Strains Found in Human and Fish with High Penicillin and Cefotaxime Non-Susceptibilities
Li Carmen, Sapugahawatte Dulmini Nanayakkara, Yang Ying, Wong Kam Tak, Lo Norman Wai Sing, Ip Margaret ( 2020 )
Microorganisms
Publication in refereed journal
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microorganisms-08-01055.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.3390/microorganisms8071055
Nusbiarylins inhibit transcription and target virulence factors in bacterial pathogen Staphylococcus aureus
Chu AJ, Qiu Y, Harper R, Lin L, Cong Ma, Yang X ( 2020 )
Publication in refereed journal
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ijms-21-05772-v2.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.3390/ijms21165772
Persistence and clearance of oral human papillomavirus infections: a prospective population-based cohort study
Martin CS Wong, Alexander C Vlantis, Miaoyin Liang, Po Yee Wong, Wendy CS Ho, Siaw S Boon, Colette Leung, Paul KS Chan, Zigui Chen ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1002/jmv.26130
Predicting the dominant influenza A serotype by quantifying mutation activities
Lou JZ, Zhao S, Cao LR, Chong MKC, Chan RWY, Chan PKS, Zee BCY, Yeoh EK, Wang MHT ( 2020 )
Publication in refereed journal
View Full-text in CUHK:
1-s2.0-S1201971220306822.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.ijid.2020.08.053
Prevalence and associated factors for carriage of Enterobacteriaceae producing ESBLs or carbapenemase and methicillin-resistant Staphylococcus aureus in Hong Kong community
Kin-On Kwok, Emily Chan, Pui-Hong Chung, Arthur Tang , Wan-In Wei, Chendi Zhu, Steven Riley, Margaret Ip ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jinf.2020.05.033
Prevalence and Characteristics of Extended-Spectrum-β-Lactamase-Producing and Carbapenemase-Producing Enterobacteriaceae from Freshwater Fish and Pork in Wet Markets of Hong Kong
Sapugahawatte DN, Li C, Zhu C, Dharmaratne P, Wong KT, Lo N, Ip M ( 2020 )
mSphere
Publication in refereed journal
View Full-text in CUHK:
mSphere-2020-Sapugahawatte-e00107-20.full.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1128/mSphere.00107-20
Prospective Study Comparing Deep Throat Saliva With Other Respiratory Tract Specimens in the Diagnosis of Novel Coronavirus Disease 2019
Lai CKC, Chen ZG, Lui G, Ling L, Li T, Wong MCS, Ng RWY, Tso EYK, Ho T, Fung KSC, Ng ST, Wong BKC, Boon SS, Hui DSC, Chan PKS ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1093/infdis/jiaa487
Prospective Study Comparing Deep Throat Saliva With Other Respiratory Tract Specimens in the Diagnosis of Novel Coronavirus Disease 2019
Lai CKC, Chen Z, Lui G, Ling L, Li T, Wong MCS, Ng RWY, Tso EYK, Ho T, Fung KSC, Ng ST, Wong BKC, Boon SS, Hui DSC, Chan PKS ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1093/infdis/jiaa487
Quantifying the importance of the key sites on haemagglutinin in determining the selection advantage of influenza virus: Using A/H3N2 as an example
Zhao S, Lou JZ, Cao LR, Chen ZG, Chan RWY, Chong MKC, Zee BCY, Chan PKS, Wang MHT ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jinf.2020.05.066
Regional differences in temporal incidence of Clostridium difficile infection: a systematic review and meta-analysis
Ho J, Wong SH, Doddangoudar VC, Boost MV, Tse G, Ip M ( 2020 )
AMERICAN JOURNAL OF INFECTION CONTROL
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.ajic.2019.07.005
Sa1915 Population-level configurations of gut mycobiome across six ethnicities in urban and rural China
Yang Sun, Tao Zuo, Chun Pan Cheung, Junkun Niu, Yating Wan, Fen Zhang, Yun Kit Yeoh, Jun Yu, Joseph J. Sung, Paul K. Chan, Francis K. Chan, Kunhua Wang, Siew C. Ng, Yinglei Miao ( 2020 )
Refereed conference paper presented and published in conference proceedings
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/S0016-5085(20)31874-6
SARS-CoV-2 detection by nasal strips: a superior tool for surveillance of paediatric population
Renee WY Chan, Kate C Chan, Kathy YY Chan, Grace CY Lui, Joseph GS Tsun, Rity YK Wong, Michelle WL Yu, Maggie HT Wang, Paul KS Chan, Hugh Simon Lam, Albert M Li ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jinf.2020.11.009
SARS-CoV-2 Detection by Nasal Strips: A Versatile Tool for Self-Screening
Renee WY Chan, Kate C Chan, Kathy YY Chan, Grace CY Lui, Joseph GS Tsun, Rity YK Wong, Michelle WL Yu, Maggie HT Wang, Paul KS Chan, Hugh Simon Lam, Albert M Li ( 2020 )
Refereed conference paper presented and published in conference proceedings
SARS-CoV-2 RNA Detection on Disposable Wooden Chopsticks, Hong Kong
Lui G, Lai CKC, Chen Z, Tong SLY, Ho WCS, Yeung ACM, Boon SS, Ng RWY, Chan PKS ( 2020 )
Emerging infectious diseases
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.3201/eid2609.202135
Scientific frontiers in faecal microbiota transplantation: joint document of Asia-Pacific Association of Gastroenterology (APAGE) and Asia-Pacific Society for Digestive Endoscopy (APSDE)
Siew C Ng, Michael A Kamm, Yun Kit Yeoh, Paul K S Chan, Tao Zuo, Whitney Tang, Ajit Sood, Akira Andoh, Naoki Ohmiya, Yongjian Zhou, Choon Jin Ooi, Varocha Mahachai, Chun-Ying Wu, Faming Zhang, Kentaro Sugano, Francis K L Chan ( 2020 )
Gut
Publication in refereed journal
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Scientific frontier in faecal microbiota transplantation.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1136/gutjnl-2019-319407
Screening FMT donors during the COVID-19 pandemic: a protocol for stool SARS-CoV-2 viral quantification
Ng SC, Chan FKL, Chan PKS ( 2020 )
The lancet. Gastroenterology & hepatology
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/S2468-1253(20)30124-2
Seasonal dynamics and starvation impact on the gut microbiome of urochordate ascidian Halocynthia roretzi
Wei Jiankai, Gao Hongwei, Yang Yang, Liu Haiming, Yu Haiyan, Chen Zigui, Dong Bo ( 2020 )
Publication in refereed journal
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s42523-020-00048-2.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1186/S42523-020-00048-2
Severe Group A and Group B Streptococcus diseases at a Pediatric ICU: Are they still sensitive to the penicillins?
Kam Lun Hon, Tai Cheong Chow, Tsun Sum Cheung, Wai Tin Lam, Lok Tin Hung, King Woon So, Margaret Ip, Su Yun Qian ( 2020 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.2174/1574884714666190926124714
Southern Chinese populations harbour non-nucleatum Fusobacteria possessing homologues of the colorectal cancer-associated FadA virulence factor
Yeoh YK, Chen Z, Wong MCS, Hui M, Yu J, Ng SC, Sung JJY, Chan FKL, Chan PKS ( 2020 )
Gut
Publication in refereed journal
View Full-text in CUHK:
1998.full.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1136/gutjnl-2019-319635
Stringent containment measures without complete city lockdown to achieve low incidence and mortality across two waves of COVID-19 in Hong Kong
Wong MCS, Ng RWY, Chong KC, Lai CKC, Huang J, Chen Z, Boon SS, Chan PKS ( 2020 )
BMJ Global Health
Publication in refereed journal
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e003573.full.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1136/bmjgh-2020-003573
Swine methicillin-resistant Staphylococcus aureus carrying toxic-shock syndrome toxin gene in Hong Kong, China
Sapugahawatte Dulmini Nanayakkara, Li Carmen, Yeoh Yun Kit, Dharmaratne Priyanga, Zhu Chendi, Ip Margaret ( 2020 )
Emerging Microbes & Infections
Publication in refereed journal
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Swine methicillin resistant Staphylococcus aureus carrying toxic shock syndrome toxin gene in Hong Kong China.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1080/22221751.2020.1785335
Synthesis and In Vitro Photodynamic Activity of Cationic Boron Dipyrromethene-Based Photosensitizers Against Methicillin-Resistant Staphylococcus aureus
Priyanga DHARMARATNE, Roy C H WONG, Jun WANG, Pui-Chi LO, Baiyan WANG, Ben C L CHAN, Kit-Man LAU, Clara B S LAU, Kwok-Pui FUNG, Margaret IP, Dennis K P NG ( 2020 )
Publication in refereed journal
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10.3390_biomedicines8060140.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.3390/biomedicines8060140
Systematic review of human gut resistome studies revealed variable definitions and approaches
Jeffery Ho, Yun Kit Yeoh, Nilakshi Barua, Zigui Chen, Grace Lui, Sunny H Wong, Xiao Yang, Martin CW Chan, Paul KS Chan, Peter M Hawkey, Margaret Ip ( 2020 )
Publication in refereed journal
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Systematic review of human gut resistome studies revealed variable definitions and approaches.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1080/19490976.2019.1700755
The Practice of Gastrointestinal Motility Laboratory During COVID-19 Pandemic: Position Statements of the Asian Neurogastroenterology and Motility Association (ANMA-GML-COVID-19 Position Statements)
Siah KTH, Rahman MM, Ong AML, Soh AYS, Lee YY, Xiao Y, Sachdeva S, Jung KW, Wang YP, Oshima T, Patcharatrakul T, Tseng PH, Goyal O, Pang J, Lai CKC, Park JH, Mahadeva S, Cho YK, Wu JCY, Ghoshal UC, Miwa H ( 2020 )
Journal of neurogastroenterology and motility
Publication in refereed journal
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JNM026-03-03.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.5056/jnm20107
Viral dynamics of SARS-CoV-2 across a spectrum of disease severity in COVID-19
Lui G, Ling L, Lai CK, Tso EY, Fung KS, Chan V, Ho TH, Luk F, Chen Z, Ng JK, Chow KM, Cheng PK, Chan RC, Tsang DN, Gomersall CD, Hui DS, Chan PK ( 2020 )
The Journal of infection
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jinf.2020.04.014
Adaptation of host transmission cycle during Clostridium difficile speciation
Kumar N, Browne HP, Viciani E, Forster SC, Clare S, Harcourt K, Stares MD, Dougan G, Fairley DJ, Roberts P, Pirmohamed M, Clokie MRJ, Jensen MBF, Hargreaves KR, Ip M, Wieler LH, Seyboldt C, Norén T, Riley TV, Kuijper EJ, Wren BW, Lawley TD ( 2019 )
Nature genetics
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1038/s41588-019-0478-8
An Interim Analysis on the First Hong Kong Chinese Newborn Microbiome Cohort - Smart Baby (Stool Microbiome & Allergic Reaction Study)
Paul KS Chan, TF Leung, WH Tam, YK Yeoh, Apple CM Yeung, Jenifer WK Yau ( 2019 )
Refereed conference paper presented and published in conference proceedings
Antibiotic-Resistant Community-Acquired Bacterial Pneumonia
Ho J., Ip M. ( 2019 )
Infectious Disease Clinics of North America
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.idc.2019.07.002
A randomized controlled trial evaluating efficacy of promoting human papillomavirus (HPV) vaccination among Chinese men who have sex with men
Wang Z, Lau JT, Ip M, Lam PKP, Fong F, Chan P ( 2019 )
Refereed conference paper presented and published in conference proceedings
Are reusable blood collection tube holders the culprit for nosocomial hepatitis C virus transmission?
Tsang DNC, Ip M, Chan PKS, Ching PTY, Lam HS, Seto WH ( 2019 )
Infection Control and Hospital Epidemiology
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1017/ice.2018.302
A Small RNA Transforms the Multidrug Resistance of Pseudomonas aeruginosa to Drug Susceptibility
Law COK, Huang C, Pan Q, Lee J, Hao Q, Chan TF, Lo NWS, Ang IL, Koon A, Ip M, Chan E, Lau TCK ( 2019 )
Molecular Therapy - Nucleic Acids
Publication in refereed journal
View Full-text in CUHK:
95486376.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.omtn.2019.02.011
Bioﬁlm production among bloodstream isolates of Candida albicans, C. tropicalis and C. parapsilosis
Y Poon, M Hui ( 2019 )
Other conference paper
Clinical Implications of Unmasking Dormant Conduction After Circumferential Pulmonary Vein Isolation in Atrial Fibrillation Using Adenosine: A Systematic Review and Meta-Analysis
Chen C, Li DB, Ho J, Liu T, Li XT, Wang Z, Lin YJ, Zou FQ, Tse G, Xia YL ( 2019 )
Frontiers in Physiology
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.3389/fphys.2018.01861
Comparison of high-flow nasal cannula versus oxygen face mask for environmental bacterial contamination in critically ill pneumonia patients: a randomized controlled crossover trial
Leung, Joynt, Gomersall, Wong, Lee, Ling, Chan, Lui, Tsoi, Ling, Hui ( 2019 )
The Journal of hospital infection
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jhin.2018.10.007
Design, synthesis and biological evaluation of antimicrobial diarylimine and -amine compounds targeting the interaction between the bacterial NusB and NusE proteins
Yangyi Qiu, Shu Ting Chan, Lin Lin, Tsun Lam Shek, Tsz Fung Tsang, Nilakshi Barua, Yufeng Zhang, Margaret Ip, Paul Kay-sheung Chan, Nicolas Blanchard, Gilles Hanquet, Zhong Zuo, Xiao Yang, Cong Ma ( 2019 )
European journal of medicinal chemistry
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.ejmech.2019.05.090
Detection of Human Pegivirus in Blood of Immunocompromised Children with Acute Myeloid Leukemia
Martin Chi-Wai Chan, Kirran N. Mohammad, Lin-Yao Zhang, Wai-Ling Lam, Frankie W.T. Cheng, Paul K.S. Chan ( 2019 )
Refereed conference paper presented and published in conference proceedings
Donor Fungi and Bacteria Engraftment After Successful Eradication of Carbapenem-Resistant Enterobacteriaceae with Fecal Microbiota Transplantation: Serial Fecal Metagenomics Analysis
Liu Q, Yang K, XU Z, Zuo T, Tang W, Zhang F, Lau LHS, Lui RN, Wong R, Chin ML, Chan PK, Chan FK, Lui GC, Ng SC ( 2019 )
Gastroenterology
Refereed conference paper presented and published in conference proceedings
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/S0016-5085(19)37116-1
Early-life Emollient Use and Skin Hydration are Predictive Factors for Infantile Eczema in Chinese Babies
Ting Fan Leung, Shuk Man Li, Ye-Hao Chen, Jennifer Wing Ki Yau, Agnes Sze Yin Leung, Kate Ching Ching Chan, Cecily Woon Wa Leung, Nam Sze Cheng, Mei Kam Chang, Paul Kay Sheung Chan, Wing Hung Tam ( 2019 )
Refereed conference paper presented and published in conference proceedings
Economic Analysis of Herpes Zoster in a Hospital Setting in Hong Kong
Wai-kit Ming, Wing-yin Yu, Owen Tak-yin Tsang, Paul Kay-sheung Chan, Joyce Hoi-sze You ( 2019 )
Acta dermato-venereologica
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.2340/00015555-3118
Effectiveness of antimicrobial hospital curtains on reducing bacterial contamination—A multicenter study
Luk S, Chow VCY, Yu KCH, Hsu EK, Tsang NC, Chuang VWM, Lai CKC, Hui M, Lee RA, Lai WM, Que TL, Fung SC, To WK, Cheng VCC, Wong ATY ( 2019 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1017/ice.2018.315.
Establishment of three human intestinal enteroid lines to study human norovirus infection
Jenny C.M. Chan, Kirran N. Mohammad, Sunny Hei Wong, Martin Chi-Wai Chan ( 2019 )
Refereed conference paper presented and published in conference proceedings
Evaluation of Oral Cavity DNA Extraction Methods on Bacterial and Fungal Microbiota
Rosenbaum, Usyk, Chen, Zolnik, Jones, Waldron, Dowd, Thorpe, Burk ( 2019 )
Scientific reports
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1038/s41598-018-38049-6
Evaluation of potential herb-drug interactions between oseltamivir and commonly used anti-influenza Chinese medicinal herbs
Yufeng Zhang, Chunming Lyu, Sophia Yui Kau Fong, Qian Wang, Chenrui Li, Nicolas James Ho, Kay Sheung Chan, Xiaoyu Yan, Zhong Zuo ( 2019 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jep.2019.112097
Evolution and global transmission of a multidrug-resistant, community-associated methicillin-resistant staphylococcus aureus lineage from the Indian subcontinent
Eike J. Steinig, Sebastian Duchene, D. Ashley Robinson, Stefan Monecke, Maho Yokoyama, Maisem Laabei, Peter Slickers, Patiyan Andersson, Deborah Williamson, Angela Kearns, Richard V. Goering, Elizabeth Dickson, Ralf Ehricht, Margaret Ip, Matthew V. N. O’Sullivan, Geoffrey W. Coombs, Andreas Petersen, Grainne Brennan, Anna C. Shore, David C. Coleman, Annalisa Pantosti, Herminia de Lencastre, Henrik Westh, Nobumichi Kobayashi, Helen Heffernan, Birgit Strommenger, Franziska Layer, Stefan Weber, Hege Vangstein Aamot, Leila Skakni, Sharon J. Peacock, Derek Sarovich, Simon Harris, Julian Parkhill, Ruth C. Massey, Mathew T. G. Holden, Stephen D. Bentley, Steven Y. C. Tong ( 2019 )
mBio
Publication in refereed journal
View Full-text in CUHK:
143798099.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1128/mBio.01105-19
Faecal microbiota transplantation for treatment of recurrent or refractory Clostridioides difficile infection in Hong Kong
Lui, Wong, Lau, Chan, Cheung, Li, Chin, Tang, Ching, Lam, Chan, Wu, Sung, Chan, Ng ( 2019 )
Hong Kong medical journal = Xianggang yi xue za zhi
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.12809/hkmj197855
Fecal microbiota transplantations reconstitute gut fungal and viral microbiota in graft-versus-host disease
Zhang F, Yeoh YK, Zuo T, Cheng F, Tang W, Cheung K, Yang K, Liu Q, Cheung CP, Mo CC, Hui M, Chan F, Li C, Chan P ( 2019 )
Gut; Gut
Refereed conference paper presented and published in conference proceedings
Digital Object Identifier (DOI): http://dx.doi.org/10.1136/gutjnl-2019-IDDFAbstracts.172
First-In-Class Inhibitors Targeting the Interaction between Bacterial RNA Polymerase and Sigma Initiation Factor Affect the Viability and Toxin Release of Streptococcus pneumoniae
J Ye, AJ Chu, L Lin, X Yang, C Ma ( 2019 )
Molecules
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.3390/molecules24162902
Genetic Susceptibility of Hong Kong Ethnic Chinese to Severe Influenza and RSV Infections
Chan Martin Chi Wai, Lee Nelson, Ma Ronald Ching Wan, Graham Colin A, Chan Paul Kay Sheung ( 2019 )
Refereed conference paper presented and published in conference proceedings
Genetic susceptibility to Tuberculosis: Interaction between HLA-DQA1 and age of onset
Tang NLS, Wang XY, Chang KC, Chan CY, Szeto NWS, Huang D, Wu JY, Lui GCY, Leung CC, Hui M ( 2019 )
INFECTION GENETICS AND EVOLUTION
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.meegid.2018.12.014
Global Pediatric Norovirus Surveillance Network (NoroSurv)
Vinje J, Selvarangan R, Pietsch C, Bonifacio J, Pang X, Rahman M, Giri S, Sakon N, Chan M ( 2019 )
Refereed conference paper presented and published in conference proceedings
Gut mucosal virome alterations in ulcerative colitis
Zuo T, Lu XJ, Zhang Y, Cheung CP, Lam S, Zhang F, Tang W, Ching JYL, Zhao R, Chan PKS, Sung JJY, Yu J, Chan FKL, Cao Q, Sheng JQ, Ng SC ( 2019 )
Gut
Publication in refereed journal
View Full-text in CUHK:
Gut mucosal virome alterations in ulcerative colitis.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1136/gutjnl-2018-318131
Higher viral load of emerging norovirus GII.P16-GII.2 than pandemic GII.4 and epidemic GII.17, Hong Kong, China
Sarah K.C. Cheung, Kirsty Kwok, Lin-Yao Zhang, Kirran N. Mohammad, Grace C.Y. Lui, Nelson Lee, E. Anthony S. Nelson, Raymond W.M. Lai, Ting F. Leung, Paul K.S. Chan, Martin Chi-Wai Chan ( 2019 )
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.3201/eid2501.180395
Human organoids: past, present, and future
Martin Chi-Wai Chan, Jenny C.M. Chan ( 2019 )
Chapter in an edited book (author)
Human papillomavirus 16 sub-lineage dispersal and cervical cancer risk worldwide: Whole viral genome sequences from 7116 HPV16-positive women
Clifford G., Tenet V., Georges D., Alemany L., Pavón M., Chen Z., Yeager M., Cullen M., Boland J., Bass S., Steinberg M., Raine-Bennett T., Lorey T., Wentzensen N., Walker J., Zuna R., Schiffman M., Mirabello L. ( 2019 )
Papillomavirus Research
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.pvr.2019.02.001
Human papillomavirus E6 oncoprotein interacts with Aurora kinase B
Siaw Shi Boon, KYC Lee, PKS Chan ( 2019 )
Refereed conference paper presented and published in conference proceedings
Human papillomavirus type 18 oncoproteins exert their oncogenicity in esophageal and tongue squamous cell carcinoma cell lines distinctly
Siaw Shi Boon, Zigui Chen, Jintao Li, Karen Y. C. Lee, Liuyang Cai, Rugang Zhong, Paul K. S. Chan ( 2019 )
BMC Cancer
Publication in refereed journal
View Full-text in CUHK:
s12885-019-6413-7.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1186/s12885-019-6413-7
Impact of inter- and intra-individual variation, sample storage and sampling fraction on human stool microbial community profiles
Yeoh YK, Chen ZG, Hui MM, Wong MCS, Ho WCS, Chin ML, Ng SC, Chan FKL, Chan PKS ( 2019 )
PEERJ
Publication in refereed journal
View Full-text in CUHK:
peerj-6172.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.7717/peerj.6172
Impact of Preservation Method and 16S rRNA Hypervariable Region on Gut Microbiota Profiling
Zigui Chen, Pak Chun Hui, Mamie Hui, Yun Kit Yeoh, Po Yee Wong, Martin C. W. Chan, Martin C. S. Wong, Siew C. Ng, Francis K. L. Chan, Paul K. S. Chan ( 2019 )
mSystems
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1128/mSystems.00271-18
Increased Bacteriophage Abundance and Loss of Viralbacterial Interactions in the Mucosa of Ulcerative Colitis: Key to Pathogenesis?
Zuo T, Lu X, Cheung CP, Lam S, Zhang F, Tang W, Ching JY, Zhao R, Chan PK, Sung JJ, Yu J, Chan FK, Sheng J, Ng SC ( 2019 )
Gastroenterology
Refereed conference paper presented and published in conference proceedings
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/S0016-5085(19)36903-3
Initial experience of faecal microbiota transplantation with frozen stools for the treatment of recurrent or refractory clostridioides difficile infection – a retrospective review from a quaternary referral centre in Hong Kong
Lui R, Lau L, Chan T, Wong S, Cheung K, Li A, Chin M, Tang W, Ching J, Lam K, Chan P, Wu J, Sung J, Chan F, CNG S ( 2019 )
Gut; Gut
Refereed conference paper presented and published in conference proceedings
Digital Object Identifier (DOI): http://dx.doi.org/10.1136/gutjnl-2019-IDDFAbstracts.189
In vitro inhibition on biofilm production of Candida species by probiotic Lactobacillus strains
Y Poon, M Hui ( 2019 )
Other conference paper
Liquid biopsy of HPV DNA in cervical cancer
Tak Hong Cheung, So Fan Yim, Mei Yun Yu, Michael J. Worley, Stephen J. Fiascone, Rossa W.K. Chiu, Keith W.K. Lo, Nelson S.S. Siu, Martin C.S. Wong, Apple C.M. Yeung, Raymond R.Y. Wong, Zi Gui Chen, Kevin M. Elias, Tony K.H. Chung, Ross S. Berkowitz, Yick Fu Wong, Paul K.S. Chan ( 2019 )
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Publication in refereed journal
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/j.jcv.2019.03.005
Metagenomic identification and winter seasonality of picobirnavirus in stool of hospitalized patients with acute gastroenteritis
Martin Chi-Wai Chan, Lin-Yao Zhang, Liutao Guo, Paul K.S. Chan ( 2019 )
Refereed conference paper presented and published in conference proceedings
Molecular detection of respiratory pathogens and typing of human rhinovirus of adults hospitalized for exacerbation of asthma and chronic obstructive pulmonary disease
Fanny Wai-san Ko, Paul Kay-sheung Chan, Renee W. Y. Chan, Ka-Pang Chan, April Ip, Angela Kwok, Jenny Chun-li Ngai, So-Shan Ng, Chan Tat On, David Shu-cheong Hui ( 2019 )
RESPIRATORY RESEARCH
Publication in refereed journal
View Full-text in CUHK:
141776791.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1186/s12931-019-1181-0
Molecular epidemiological study of enterovirus D68 in hospitalised children in Hong Kong in 2014-2015 and their complete coding sequences
Haichao Wang, Kin Pong Tao, Cheuk Yin Leung, Kam Lun Hon, Apple CM Yeung, Zigui Chen, Paul KS Chan, Ting-Fan Leung, Renee WY Chan ( 2019 )
BMJ Open Respiratory Research
Publication in refereed journal
View Full-text in CUHK:
e000437.full.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.1136/bmjresp-2019-000437
Non-human Primate Papillomaviruses Share Similar Evolutionary Histories and Niche Adaptation as the Human Counterparts
Chen Zigui, Long Teng, Wong Po Yee, Ho Wendy C.S., Burk Robert D., Chan Paul K.S. ( 2019 )
Frontiers in Microbiology
Publication in refereed journal
View Full-text in CUHK:
fmicb-10-02093.pdf
Digital Object Identifier (DOI): http://dx.doi.org/10.3389/fmicb.2019.02093
Norovirus-induced immune response in human intestinal enteroids
Chan J, Mohammad K, Zhang L, Wong S, Chan M ( 2019 )
Refereed conference paper presented and published in conference proceedings
Norovirus Virus-like Particles - Good Surrogates for Native Virions in Binding Analyses?
Martin Chi-Wai Chan, Sarah K.C. Cheung ( 2019 )
Refereed conference paper presented and published in conference proceedings

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