Autophagy in intracellular bacterial infection
Publication in refereed journal

替代計量分析
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其它資訊
摘要Autophagy is a conserved intracellular degradation process enclosing the bulk of cytosolic components for lysosomal degradation to maintain cellular homeostasis. Accumulating evidences showed that a specialized form of autophagy, known as xenophagy, could serve as an innate immune response to defend against pathogens invading inside the host cells. Correspondingly, infectious pathogens have developed a variety of strategies to disarm xenophagy, leading to a prolonged and persistent intracellular colonization. In this review, we first summarize the current knowledge about the general mechanisms of intracellular bacterial infections and xenophagy. We then focus on the ongoing battle between these two processes.
出版社接受日期30.07.2019
著者Hu W, Chan H, Lu L, Wong KT, Wong SH, Li MX, Xiao ZG, Cho CH, Gin T, Chan MTV, Wu WKK, Zhang L
期刊名稱Seminars in Cell and Developmental Biology
出版年份2020
月份5
卷號101
出版社Elsevier
頁次41 - 50
國際標準期刊號1084-9521
語言英式英語
關鍵詞Xenophagy, Intracellular bacteria, Infection

上次更新時間 2020-17-09 於 04:02