New insights and therapeutic implication of gut microbiota in non-alcoholic fatty liver disease and its associated liver cancer
Publication in refereed journal

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摘要The gastrointestinal tract represents one of the largest interfaces between the host and environmental factors. It contains a vast and complex community of microbes, forming what is collectively known as the microbiota. This gut microbiota plays a pivotal role in the maintenance of health, and 'dysbiosis' of the gut microbiota, commonly considered as perturbation of microbiota diversity and composition, has been associated with intestinal and extra-intestinal diseases, including non-alcoholic fatty liver disease (NAFLD) and its associated hepatocellular carcinoma (NAFLD-HCC).

In this review, we highlight microbiota dysbiosis and the microbiota-host interactions that link to the pathogenesis of NAFLD and NAFLD-HCC. We discuss the potential therapeutic implications of the gut microbiota in the progression of NAFLD-HCC.
著者Niama Ezzaidi, Xiang Zhang, Olabisi Oluwabukola Coker, Jun Yu
期刊名稱Cancer Letters
出版年份2019
月份9
日期10
卷號459
頁次186 - 191
國際標準期刊號0304-3835
語言美式英語

上次更新時間 2020-21-10 於 02:54