Overview of systematic reviews with meta-analyses on acupuncture in post-stroke cognitive impairment and depression management
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AbstractBackground: Acupuncture has been using as an alternative non-pharmacological therapy in the management of post stroke depression and cognitive impairment but its effectiveness and safety remain controversial. We conducted an overview of systematic reviews with meta-analyses to evaluate the evidence on the effect of acupuncture in the treatment of stroke with conventional medicine intervention.
Methods: Systematic reviews summarized the treatment effects of acupuncture for post stroke cognitive impairment and post stroke depression were considered eligible. Methodological quality of included systematic reviews was assessed using A MeaSurement Tool to Assess systematic Reviews 2 (AMSTAR 2).
Results: Four systematic reviews on post stroke cognitive impairment and ten systematic reviews on post stroke depression with good methodological quality were included. Meta-analyses revealed that acupuncture plus cognitive rehabilitation; and acupuncture or moxibustion plus cognitive rehabilitation, versus cognitive rehabilitation demonstrated statistically significant increase in Mini-Mental State Examination scores in compared to cognitive rehabilitation after 4 weeks treatment [Pooled weighted mean difference (WMD)= 3.14, 95% confidence interval (CI)= 2.06 to 4.21, I2 = 36%]; and (Pooled WMD= 3.22, 95% CI= 2.09 to 4.34, I2 = 0%). Furthermore, acupuncture versus antidepressant demonstrated statistically significant improve depression measured by increasing in 17-item Hamilton Depression Rating Scale in comparing to cognitive rehabilitation after 2 weeks treatment (Pooled WMD= -2.34, 95% CI= -3.46 to -1.22, I2 = 5%). Acupuncture usage was not associated with increased risk of adverse events.
Conclusions: Acupuncture is safe and improves cognitive function and depressive disorder without obvious serious adverse events for post stroke patients.
Acceptance Date01/05/2019
All Author(s) ListCaroline Yik-fong Hung, Xin-yin Wu, Vincent Chi-ho Chung, Endy Chun-hung Tang, Justin Che-yuen Wu, Alexander Yuk-lun Lau
Journal nameIntegrative Medicine Research
Volume Number8
Issue Number3
Pages145 - 159
LanguagesEnglish-United Kingdom
KeywordsSystematic review, acupuncture, cognitive impairment, depression, stroke

Last updated on 2020-28-03 at 02:19