Comparison of portable blood-warming devices under simulated pre-hospital conditions: a randomised in-vitro blood circuit study
Publication in refereed journal

香港中文大學研究人員
替代計量分析
.

其它資訊
摘要Pre-hospital transfusion of blood products is a vital component of many advanced pre-hospital systems. Portable fluid warmers may be utilised to help prevent hypothermia, but the limits defined by manufacturers often do not reflect their clinical use. The primary aim of this randomised in-vitro study was to assess the warming performance of four portable blood warming devices (Thermal Angel, Hypotherm X LG, °M Warmer, BuddyLite)againstcontrolatdifferentclinically-relevantflowrates.Thesecondaryaimwastoassesshaemolysis ratesbetweendevicesatdifferent flowrates.Weassessedeachofthefourdevicesandthecontrol,at flowrates of50 ml.min1,100 ml.min1 and200 ml.min1,usingacontrolledperfusioncircuitwithmultisitetemperature monitoring.Freehaemoglobinconcentration, amarker ofhaemolysis,wasmeasuredatmultiplepointsduring each initial study run with spectrophotometry. At all flow rates, the four devices provided superior warming performance compared with the control (p < 0.001). Only the °M Warmer provided a substantial change in temperatureatallflowrates(mean(95%CI)temperaturechangeof21.1(19.8–22.4) C,20.4(19.1–21.8) Cand 19.4 (17.7–21.1) C at 50 ml.min1, 100 ml.min1 and 200 ml.min1, respectively). There was no association between warming and haemolysis with any device (p = 0.949) or flow rate (p = 0.169). Practical issues, which may be relevant to clinical use, also emerged during testing. Our results suggest that there were significant differences in the performance of portable blood warming devices used at flow rates encountered in clinical practice.
出版社接受日期29.03.2019
著者A.Weatherall, M.Gill, J.Milligan, C.Tetlow, C.Harris, A.Garner, A.Lee
期刊名稱Anaesthesia
出版年份2019
月份8
卷號74
期次8
出版社Wiley
頁次1026 - 1032
國際標準期刊號0003-2409
電子國際標準期刊號1365-2044
語言英式英語

上次更新時間 2020-28-11 於 02:11