Noneffectiveness of electroacupuncture for comorbid generalized anxiety disorder and irritable bowel syndrome
Publication in refereed journal


引用次數
替代計量分析
.

其它資訊
摘要BACKGROUND AND AIM:
Comorbid generalized anxiety disorder and irritable bowel syndrome are common and therapeutically challenging. We aimed to assess the effectiveness of electroacupuncture in relieving anxiety and bowel symptoms in Chinese adults with this form of comorbidity.

METHODS:
In a single-blind randomized sham-controlled trial, subjects with comorbid generalized anxiety disorder and irritable bowel syndrome were randomly assigned to receive 10 weekly sessions of electroacupuncture or sham electroacupuncture. Patients were assessed at baseline, immediately after intervention and at 6-week follow-up. Primary outcome was anxiety (7-item Patient Health Questionnaire section for anxiety). Secondary outcomes included bowel symptoms (bowel symptoms questionnaire), depressive symptoms (9-item Patient Health Questionnaire), somatic symptoms (15-item Patient Health Questionnaire), and health-related quality of life (EuroQol-5 Dimensions).

RESULTS:
Eighty subjects, 40 in each arm, were randomized. All but two in the sham group completed 10 weekly sessions. There was no significant difference in the proportion of patients experiencing significant (≥ 50%) reduction of anxiety symptoms between the two groups immediately after intervention (32.4% vs 21.6%, P = 0.06) and at 6-week follow-up (25.7% in electroacupuncture vs 27% in sham, P = 0.65). Anxiety, depressive symptom, and bowel symptom severity did not differ significantly between electroacupuncture and sham groups.

CONCLUSIONS:
Findings failed to support the effectiveness of electroacupuncture for comorbid generalized anxiety disorder and irritable bowel syndrome. Further studies are needed to identify effective acupuncture treatment protocols for such comorbidity.
出版社接受日期15.03.2019
著者Arthur Dun‐Ping Mak, Vincent Chi Ho Chung, Suet Ying Yuen, Yee Kit Tse, Samuel Yeung Shan Wong, Yanli Ju, Sheung Sheung Hung, Ka Chun Leung, Joyce Hoi Sze You, Rashid Lui, Sunny Hei Wong, Owen Ngo Wang Leung, Linda Chiu Wa Lam, Sing Lee, Justin Che Yuen Wu
期刊名稱Journal of Gastroenterology and Hepatology
出版年份2019
月份10
卷號34
期次10
出版社Wiley
頁次1736 - 1742
國際標準期刊號0815-9319
電子國際標準期刊號1440-1746
語言英式英語

上次更新時間 2020-24-10 於 03:48