Preliminary results of a randomized controlled trial evaluating efficacy of promoting Human Papillomavirus (HPV) vaccination among Chinese men who have sex with men
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AbstractIntroduction & purpose: HPV-related disease burden is high among men who have sex with men (MSM). HPV vaccination is highly effective in preventing HPV-related diseases among men but under-utilized by Chinese MSM. The primary objective of the randomized controlled trial (RCT) study is to evaluate the relative efficacies of two online, theory-based and interactive interventions [online health communication with and without motivational interviewing (MI)] in increasing uptake of three required doses of HPV vaccination within a 9-month follow-up period among Hong Kong Chinese MSM, as compared to the control group.
Methods: A three-arm parallel-group, non-blinded randomized controlled trial was conducted. Participants were Hong Kong Chinese speaking MSM who had never received HPV vaccination. A total of 624 eligible MSM will be recruited and randomized 1:1:1 into three groups: 1) Group HC (Online Health Communication Only Group): exposure to interactive and theory-based online health communication promoting HPV vaccination among MSM, 2) Group HC-MI (Online Health Communication plus MI): receiving 15-minute MI over phone, administered by a trained fieldworkers, on top of the health promotion given to Group HC, and 3) Control group: exposure to online health communication related to mental health that was unrelated to HPV vaccination. Participants were given coded discount coupons (10% discount of the market price) for taking up the three doses of HPV vaccines at a collaborating private clinic. To date, 578 participants completed the baseline telephone survey and were assigned to Group HC (n=207), Group HC-MI (n=191) and the control group (n=180); 162 participants (56 in Group HC, 63 in Group HC-MI, and 43 in the control group) completed the Month 3 follow-up.
Results: Among those who have completed the Month 3 follow-up, the uptake of the first dose of HPV vaccination was 14.3% (8/56) in Group HC, 54.0% (34/63) in Group HC-MI and 23.2% (10/43) in the control group. The uptake was significantly higher in the Group HC-MI than that of the control group (RR: 2.32, 95%CI: 1.29, 4.18; ARR: 30.7, 95%CI: 13.1, 48.3; p<0.001).
Conclusions: The theory-based online health communication plus brief MI is of good potential to increase HPV vaccination uptake among Hong Kong Chinese MSM.
All Author(s) ListZixin Wang, Joseph T.F. Lau, Mary Ip, Polly P.K. Lam, Francois Fong, Paul Chan
Name of Conference2018 International Congress of Behavioral Medicine
Start Date of Conference14/11/2018
End Date of Conference17/11/2018
Place of ConferenceSatiago, Chile
Country/Region of ConferenceRepublic of Chile
Proceedings TitleInternational Journal of Behavioral Medicine
Volume Number25
Issue NumberSuppl 1
PagesS35 - S35
LanguagesEnglish-United States

Last updated on 2021-21-09 at 00:39