Compact high-resolution endomicroscopy based on fiber bundles and image stitching
Publication in refereed journal

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摘要In this Letter, we report a compact endomicroscope (��=2.8  mm) based on a fiber bundle and a two-axis piezoelectric tube scanner, achieving a resolution of ∼1  μm and an imaging speed of 30–120 fps. Compared with distal end scanning systems, typical fiber-bundle-based endomicroscopes achieve a more compact envelope (��∼1.5  mm) at the expense of compromised imaging quality. The resolution of fiber-bundle-based systems is largely limited by the diameter of the constituent fibers (��∼5.0  μm), where each fiber serves as a single pixel, i.e., a sampling point, in the imaging system. To retrieve the lost information, we integrate a piezo tube scanner at the tip of the fiber bundle. Next, we rapidly scan the fiber tip over a range of ±2.5  μm and combine the signals obtained at different inter-fiber locations. Direct alignment and feature-based registration methods are applied to register the raw images. Imaging experiments are performed on a resolution target and biological samples to demonstrate the performance enhancement.
出版社接受日期26.07.2018
著者Yina CHANG, Wei LIN, Jiyi CHENG, Shih-Chi CHEN
期刊名稱Optics Letters
出版年份2018
月份9
日期1
卷號43
期次17
出版社OSA
出版地USA
頁次4168 - 4171
國際標準期刊號0146-9592
電子國際標準期刊號1539-4794
語言美式英語

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