7S protein is more effective than total soybean protein isolate in reducing plasma cholesterol
Publication in refereed journal

替代計量分析
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其它資訊
摘要7S protein is one of four major storage proteins in soybean. The present study compared the relative cholesterol-lowering activity of the 7S protein with that of total soybean protein isolate (SPI). Forty-eight hamsters were divided into six groups fed non-cholesterol diet or one of five high-cholesterol diets containing 24.2% casein, 12.1–24.2% SPI, 12.1–24.2% 7S protein, respectively. Results showed the 7S protein reduced plasma total cholesterol (TC) by 20–41% while SPI reduced it by 9–16%. 7S protein increased the fecal excretion of neutral sterols by 43–116%, while SPI only had 18–68% increase. 7S protein increased the excretion of total bile acids by 208–367%, while SPI only increased it by 41–86%. 7S protein could not only down regulate gene expression of HMG-CoA reductase but also up regulate gene expression of CYP7A1. It was concluded that dietary 7S protein was more hypocholesterolemic than SPI, mediated by increasing the sterol excretion and decreasing the cholesterol synthesis.
出版社接受日期15.06.2017
著者Y Liu, J Yang, L Lei, L Wang, X Wang, KY Ma, X Yang, ZY Chen
期刊名稱Journal of Functional Foods
出版年份2017
月份9
卷號36
出版社Elsevier
頁次18 - 26
國際標準期刊號1756-4646
語言美式英語
關鍵詞Cholesterol, β-conglycinin, CYP7A1, 7S protein, Soy protein isolate, Sterols

上次更新時間 2020-27-03 於 04:04