ZNF1, a new negative regulator of brassinosteroid signaling in Arabidopsis
Invited conference paper presented and published in conference proceedings



摘要Brassinosteroids (BRs) are steroidal hormones that are essential for normal plant growth and developmental. BR signaling is mediated by a signaling pathway composed of the BR receptors BRI1/BAK1, transcription factors BZR1/BES1, and other key components. Recent studies indicated that BZR1 family of proteins mediate BR crosstalk with other signaling pathways but the detailed mechanisms are not fully understood. From a BZR1-based yeast two-hybrid screen, we identified a BZR1-interacting protein ZNF1, which is a CCCH-type zinc finger protein with putative transcriptional regulatory activity. ZNF1 and family proteins have been previously reported to be involved in plant response to abiotic stresses; however, whether they are involved in plant growth is not known. Here we show that ZNF1 interacts with BZR1 in vitro and in vivo and overexpression of ZNF1 inhibits plant growth. ZNF1 accumulation in plants is BR-inducible and overexpression of ZNF1 suppresses BZR1’sactivity in regulating plant growth, target gene expression and responses to BR treatments. Our results suggest that ZNF1 may be a new negative regulator of pant growth and BR signaling.
著者Zheze Zhao, Mei Hui Yu, Zhiyong Wang, Junxian He
會議名稱A Joint-Meeting of Institute of Plant Biology (IPB), NTU and HK RGC-Area of Excellence Center for Genomic Studies on Plant-Environment Interaction for Sustainable Agriculture and Food Security, CUHK
關鍵詞Zinc-Finger protein, brassinosteroid signaling, in Arabidopsis

上次更新時間 2018-06-11 於 09:54