Ultra-high loading of sinoporphyrin sodium in ferritin for single-wave motivated photothermal and photodynamic co-therapy
Publication in refereed journal

香港中文大學研究人員
替代計量分析
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其它資訊
摘要In this work, a potent photosensitizer, sinoporphyrin sodium (DVDMS), was loaded into RGD-modified ferritin (R-Fn) nanocages by a rapid, scalable and versatile approach for imaging guided photodynamic and photothermal (PTT/PDT) co-therapy. The resulting nanocomposite formed a well-defined nanocage with a photosensitizer loading capacity as high as 66.67 wt%, which far exceeds those reported previously. The bioengineered protein nanocage-based nanotheranostics exhibits a remarkably improved tumor treatment effect over DVDMS with good biocompatibility and the potential of clinical translation.
出版社接受日期31.05.2017
著者Chao Huang, Chengchao Chu, Xiaoyong Wang, Huirong Lin, Junqing Wang, Yun Zeng, Wenzhen Zhu, Yi-Xiang J. Wang, Gang Liu
期刊名稱Biomaterials Science
出版年份2017
月份8
卷號5
期次8
出版社Royal Society of Chemistry
頁次1512 - 1516
國際標準期刊號2047-4830
電子國際標準期刊號2047-4849
語言英式英語
關鍵詞Ultra-high, sodium, ferritin, photthermal, photodynamic

上次更新時間 2021-20-02 於 01:21