Hearing outcome of cochlear implantation for post-irradiated nasopharyngeal carcinoma (NPC) patients
Refereed conference paper presented and published in conference proceedings


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AbstractBackground: Nasopharyngeal cancer (NPC) is highly prevalent in Hong Kong and the mainstay of treatment is radiotherapy. Sensorineural haring loss is a common complication in post-irradiated NPC patients which may progress to profound deafness over years. Method and Materials: A case comparative study was conducted to evaluate the efficacy of cochlear implantation (CI) as an option of hearing rehabilitation in deafened patients who had received radiotherapy for nasopharyngeal carcinoma. In this study we retrospectively reviewed the adult patients who underwent CI in our center form 1995 to 2015 and compared the outcomes of NPC patients to non-NPC patients matched with age, sex and duration of deafness. Speech perception tests were used to assess the hearing performance of patients pre-operatively, and then at 6 months, 12 months and 24 months postoperatively using the Cantonese speech perception tests. Results: The NPC group did significantly better at the 12 months and 24 months postoperatively in terms of sentence recognition. The two groups performed similarly in the other two outcome measures, namely word recognition and tone perception within the two-year period. Discussion and Conclusion: The radiotherapy-induced damage to was the hair cells primarily while the cochlear nerve is resistant to radiation and its function was well preserved. This probably contributed the overall better performance in this group of patients. Therefore, cochlear implantation is recommended for the management of significant hearing impairment with NPC.
All Author(s) ListHenry CK Lam, WT Chang, Kammy NK Yeung, Betty PK Luk, Karman KY Leung, Michael CF Tong
Name of Conference15th International Conference on Cochlear Implants and Other Implantable Auditory Technology
Start Date of Conference27/06/2018
End Date of Conference30/06/2018
Place of ConferenceAntwerp
Country/Region of ConferenceBelgium
Proceedings TitleJournal of Hearing Science
Year2018
Month6
Volume Number8
Issue Number2
Pages123 - 123
ISSN2083-389X
eISSN2084-3127
LanguagesEnglish-United Kingdom

Last updated on 2018-22-11 at 10:36