Low-magnitude high-frequency vibration: An alternative approach for sarcopenia and bone health?
Invited conference paper presented and published in conference proceedings


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AbstractAging population is a global challenging problem and aging-induced musculoskeletal problems impose huge healthcare cost to many countries. The most common geriatric musculoskeletal problems include sarcopenia, osteoporosis and related fractures, which are highly associated to each other. To date, there are quite many available interventions to deal with osteoporosis, including physical exercise, vitamin D or pharmaceutical approaches. Sarcopenia is, however, not well studied and the recommended interventions include resistance exercise and high protein diet only but the compliance to exercise is not satisfactory, while promising medication is even not available yet. In Hong Kong, the issue of sarcopenia cannot draw sufficient attention of the general public. Furthermore, some recent clinical reports indicated that the prevalence of sarcopenia in hip fracture patients is very high up to ~70% that is alarming to orthopaedic field. Hence, an effective intervention for sarcopenia with good compliance is in pressing need.
Low-magnitude high-frequency vibration (LMHFV) is a biophysical intervention to provide systemic mechanical signals at 35Hz, 0.3g (g=gravitational acceleration) to musculoskeletal system. Previously, our laboratory has reported that LMHFV is effective to enhance fracture healing by shortening the healing time (~30%), increase blood flow and muscle performance in preclinical studies. In the meantime, a large-scale randomized controlled clinical studies involving 710 elderly demonstrated a significant reduction of fall rates in community elderly with good improvement of muscle performance and balancing ability. Based on these evidences, we therefore speculate that LMHFV may be of intriguing potential to resist against the progression of sarcopenia. With using our established sarcopenia animal model, we are trying to testify our speculation and our next goal is to conduct a clinical trial.
Acceptance Date02/12/2017
All Author(s) ListWing Hoi Cheung
Name of ConferenceMini Symposium on Nutrition and Optimal Health: Bone Health & Sarcopenia
Start Date of Conference02/12/2017
End Date of Conference02/12/2017
Place of ConferencePolyU, Hong Kong
Country/Region of ConferenceHong Kong
Year2017
Month12
Day2
LanguagesEnglish-United States
KeywordsLow-magnitude high-frequency vibration, sarcopenia, bone health

Last updated on 2018-30-10 at 16:26