Narrow band imaging endoscopy of the nasopharynx for malignancy: an inter- and intraobserver study
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摘要Objective: To assess interobserver agreement and intraobserver reproducibility when assessing the nasopharynx formalignancy under white light and narrow band imaging endoscopy because the decision to biopsy hinges on the examiner’sperceived chance of malignancy.Methods: An interobserver and intraobserver agreement study utilizing white light and narrow band endoscopic imagesof the nasopharynx. The setting was an academic referral hospital.Participants were 156 adults with suspected nasopharyngeal carcinoma who underwent white light and narrow band imagingendoscopy and biopsy. Images of the nasopharynges were subsequently scored for malignancy by four otolaryngologists.The nasopharynx was scored on 4-point scales under white light and narrow band imaging endoscopy for the likelihood ofmalignancy or abnormality, respectively.Results: Intraclass correlation coefficients for intraobserver agreement for nasopharyngeal malignancy for four observersunder white light were 0.86, 0.89, 0.79 and 0.88 (mean 0.855), respectively; and under narrow band imaging they were 0.64,0.68, 0.64, and 0.66 (mean 0.655), respectively (all P values < 0.001). The coefficient for interobserver reliability under whitelight was 0.79 (95% confidence interval [CI] 0.76–0.82; P < 0.001), which indicated strong agreement. The coefficient for inter-observer reliability under narrow band imaging was 0.56 (95% CI 0.50– 0.61; P < 0.001), which indicated moderate agreement.Conclusions: Intraobserver and interobserver agreement for nasopharyngeal malignancy was strong on white lightendoscopy but only moderate on narrow band imaging endoscopy. Agreement may be improved by adopting a standard set ofassessment guidelines, including an objective detailed morphological analysis under white light and vasculature analysis undernarrow band imaging.
出版社接受日期13.07.2018
著者Alexander C Vlantis, Eddy WY Wong, SK Ng, Jason YK Chan, Michael CF Tong
期刊名稱Laryngoscope
出版年份2019
月份6
卷號129
期次6
出版社JOHN WILEY & SONS INC
出版地New York
頁次1374 - 1379
國際標準期刊號0023-852X
電子國際標準期刊號1531-4995
語言美式英語
關鍵詞Nasopharyngeal carcinoma, narrow band imaging, endoscopy, observer variation.

上次更新時間 2020-12-09 於 02:47