What can we measure in 60 seconds? The complexity of verbal fluency test
Refereed conference paper presented and published in conference proceedings

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AbstractCategory verbal fluency test (CVFT) has been widely used to assess the cognitive functioning, but the components of CVFT and its corresponding neural underpinnings are still controversial. We aimed to combine the psychometric and morphometric approaches to decode the performance of CVFT in senior adults with different cognitive status. Methods: Capacity- and speed-based measures of CVFT were conducted in the elderly with high performing, normal ageing and neurocognitive disorders (NCD) (n = 488). Surface-based regional gray matter volume was calculated in a subsample (n = 52). Pearson correlation analysis was used to examine associations with brain volume and component-specific CVFT performance. Results: Speed-based measures showed stronger associations with other cognitive function than capacity-based measures. Meanwhile, CVFT performance showed component-specific patterns of neural correlates. Capacity-based measures were left lateralized, and speed-based measures were right lateralized. Conclusions: The complexity ofCVFT could be decomposed into multiple components, including memory, executive control and language. The capacity- and speed-based measures embedded in the domain-specific and lateralized function also highlight the underlying theoretical meaning of CVFT and its utility of tracing the cognitive trajectory in preclinical dementia.
Acceptance Date11/03/2018
All Author(s) ListLU Hanna, NI Xi, LAM Chiu Wa
Name of ConferenceAnnual Meeting of the Organization for Human Brain Mapping
Start Date of Conference17/06/2018
End Date of Conference21/06/2018
Place of ConferenceSingapore
Country/Region of ConferenceSingapore
LanguagesEnglish-United Kingdom
KeywordsNeuroimaging, Verbal function, Capacity, Speed, Grey matter volume

Last updated on 2018-03-07 at 12:31