Short Sleep Duration Is Weakly Associated with Carotid Intima-Media Thickness in Adolescents
Publication in refereed journal


To investigate the relationship between sleep duration and carotid intima-media thickness (CIMT) in adolescents. We hypothesized that short sleep duration was associated with an increased CIMT.

Study design
This was a cross-sectional study. Healthy participants aged 10-18 years were recruited from a school-based cohort established to examine the prevalence of obstructive sleep apnea in Hong Kong. All participants completed a prospective 7-day sleep diary, underwent anthropometric measurements, overnight polysomnography, and CIMT assessment. Overweight participants or those with an obstructive apnea hypopnea index of ≥5 were excluded from analysis. Regression analysis was used to assess the association between CIMT and sleep duration and other possible correlates.

One hundred forty-two participants completed the assessments. Male participants tended to have shorter sleep duration than females (P = .012). There were no differences in age, body mass index, Tanner developmental stage, or parental history of hypertension between groups of different sleep durations. There was a weak but significant association between short sleep duration and CIMT (r = −0.273; P < .001).

Sleep duration was found to have a weakly negative association with CIMT. Further research is needed to determine whether adult adverse cardiovascular events may originate in childhood owing to short sleep duration.
著者Jade Wing Sum Li, Chun Ting Au, Kate Ching Ching Chan, Ping Chook, Yun Kwok Wing, Albert Martin Li
期刊名稱Journal of Pediatrics
頁次80 - 84
關鍵詞sleep insufficiency, atherosclerosis, cardiovascular

上次更新時間 2021-16-09 於 01:16