Prevalence of levator ani muscle avulsion and effect on quality of life in women with pelvic organ prolapse
Publication in refereed journal

香港中文大學研究人員
替代計量分析
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其它資訊
摘要INTRODUCTION AND HYPOTHESIS:
Levator ani muscle (LAM) avulsion is associated with pelvic organ prolapse (POP). There is limited information on the prevalence of LAM avulsion in Chinese women with POP. This study evaluated the prevalence of LAM avulsion in women presenting with POP and the effects on their quality of life (QoL).

METHODS:
This prospective study was conducted in a tertiary urogynecology center. Chinese women presenting with POP were recruited and completed standardized questionnaires exploring their symptoms and QoL and underwent gynecological examination to assess the stage of POP and involved compartments. Four-dimensional translabial ultrasound (US) was performed on all women, and evaluation of LAM avulsion was done offline.

RESULTS:
Three hundred and ninety-eight women completed the study. The prevalence of LAM avulsion was 38.9% [95% confidence interval (CI) 34.1-43.7%]; 31 (7.8%), 26 (6.5%), and 98 (24.6%) had left, right, and bilateral LAM avulsion, respectively. LAM avulsion was associated with a more advanced stage of prolapse (P < 0.005) and prolapse of stage ≥II of all three compartments. Bilateral LAM avulsion was associated with a more severe stage of prolapse. More women with LAM avulsion reported bothersome symptoms of prolapse and had higher Pelvic Organ Prolapse Distress Inventory (POPDI) and Urinary Incontinence Questionnaire (UIQ) scores, implying more impairment in QoL. However, after multivariate linear regression analysis, POP stage remained a significant predictor of POPDI and UDI scores (P ≤ 0.006); LAM avulsion was not a predictor (P = 0.2 and 0.27, respectively).

CONCLUSIONS:
LAM avulsion was detected in 39% of Chinese women with POP. It was associated with a more advanced POP stage, and these women had more impairment of QoL. However, LAM avulsion was not an independent factor influencing the QoL of these women.
出版社接受日期10.08.2017
著者Yu CH, Chan SSC, Cheung RYK, Chung TKH
期刊名稱International Urogynecology Journal
出版年份2018
月份5
卷號29
期次5
出版社Springer London Ltd
出版地England
頁次729 - 733
國際標準期刊號0937-3462
語言英式英語
關鍵詞Levator ani muscle avulsion, Levator ani muscle injury, Pelvic organ prolapse, PFDI, PFIQ

上次更新時間 2021-13-10 於 23:36