The first phytochemical investigation of Rhododendron websterianum: triterpenoids and their cytotoxic activity
Publication in refereed journal

香港中文大學研究人員
替代計量分析
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其它資訊
摘要The first phytochemical investigation of the fruits of Rhododendron websterianum resulted in the isolation of two new triterpenoids, 11-dehydroxytrisnormogrol acid (1), 11-dehydroxytrisnormogrol (2), and 21 known analogues. Their structures were determined by extensive analysis of spectroscopic and mass data, as well as by comparison with those in literature. All isolates were assayed their cytotoxic activities on human hepatoma SMMC-7721 cells and human lung adenocarcinoma A549 cells. Three known compounds, dammarenediol II, lup-20(29)-ene-2α,3β-diol, and 19,24-dihydroxyurs-12-en-3-one-28-oic acid exhibited cytotoxic activities against these two human cancer cell lines with the IC50 values in a range of 27.4–42.8 μM.
著者Rui ZHANG, Chunping TANG, Yan LI, Chang-Qiang KE, Ge LIN, Hua XIE, Sheng YAO, Yang YE
期刊名稱Phytochemistry Letters
出版年份2018
月份6
卷號25
出版社Elsevier
頁次43 - 46
國際標準期刊號1874-3900
電子國際標準期刊號1876-7486
語言英式英語
關鍵詞Cytotoxicity, Triterpenoids, Ericaceae, Rhododendron websterianum

上次更新時間 2021-17-09 於 00:04