Association of the DYX1C1 Gene with Chinese Literacy in a Healthy Chinese Population
Refereed conference paper presented and published in conference proceedings


摘要DYX1C1, the first dyslexia candidate gene, has been associated with developmental dyslexia in different populations, but its influence on reading abilities in the general population is less well known. Copy number variants (CNVs) have been implicated in neurodevelopmental and childhood-onset disorders involving cognitive development in previous studies. In this report, we investigated the extent to which genomic CNVs for the SNP previously linked to dyslexia, -3G/A (rs3743205) in the gene DYX1C1, contribute to Chinese and English literacy in the general population in a Chinese cohort, and whether these processes, in turn, are influenced by environmental factors, such as family income, parents’ education, and IQ. Our findings suggest that the logR ratio (which is a way to detect CNVs) of a previously reported dyslexia-related SNP, -3G/A (rs3743205) is significantly associated with Chinese literacy in a cohort of Chinese children with normal reading abilities.
著者Waye Mary Miu Yee, Siu Cynthia O, McBride Catherine, Ho Connie Suk-han, Wong Cheuk Wa
會議名稱51st Hawaii International Conference on System Sciences
會議論文集題名Proceedings of the 51st Hawaii International Conference on System Sciences
頁次2804 - 2813

上次更新時間 2022-15-01 於 23:47