Association of the DYX1C1 Gene with Chinese Literacy in a Healthy Chinese Population
Refereed conference paper presented and published in conference proceedings

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其它資訊
摘要DYX1C1, the first dyslexia candidate gene, has been associated with developmental dyslexia in different populations, but its influence on reading abilities in the general population is less well known. Copy number variants (CNVs) have been implicated in neurodevelopmental and childhood-onset disorders involving cognitive development in previous studies. In this report, we investigated the extent to which genomic CNVs for the SNP previously linked to dyslexia, -3G/A (rs3743205) in the gene DYX1C1, contribute to Chinese and English literacy in the general population in a Chinese cohort, and whether these processes, in turn, are influenced by environmental factors, such as family income, parents’ education, and IQ. Our findings suggest that the logR ratio (which is a way to detect CNVs) of a previously reported dyslexia-related SNP, -3G/A (rs3743205) is significantly associated with Chinese literacy in a cohort of Chinese children with normal reading abilities.
著者Waye Mary Miu Yee, Siu Cynthia O, McBride Catherine, Ho Connie Suk-han, Wong Cheuk Wa
會議名稱51st Hawaii International Conference on System Sciences
會議開始日03.01.2018
會議完結日06.01.2018
會議地點Hawaii
會議國家/地區美國
會議論文集題名Proceedings of the 51st Hawaii International Conference on System Sciences
出版年份2018
頁次2804 - 2813
國際標準書號978-0-9981331-1-9
語言美式英語

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