Association of the DYX1C1 Gene with Chinese Literacy in a Healthy Chinese Population
Refereed conference paper presented and published in conference proceedings

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AbstractDYX1C1, the first dyslexia candidate gene, has been associated with developmental dyslexia in different populations, but its influence on reading abilities in the general population is less well known. Copy number variants (CNVs) have been implicated in neurodevelopmental and childhood-onset disorders involving cognitive development in previous studies. In this report, we investigated the extent to which genomic CNVs for the SNP previously linked to dyslexia, -3G/A (rs3743205) in the gene DYX1C1, contribute to Chinese and English literacy in the general population in a Chinese cohort, and whether these processes, in turn, are influenced by environmental factors, such as family income, parents’ education, and IQ. Our findings suggest that the logR ratio (which is a way to detect CNVs) of a previously reported dyslexia-related SNP, -3G/A (rs3743205) is significantly associated with Chinese literacy in a cohort of Chinese children with normal reading abilities.
All Author(s) ListWaye Mary Miu Yee, Siu Cynthia O, McBride Catherine, Ho Connie Suk-han, Wong Cheuk Wa
Name of Conference51st Hawaii International Conference on System Sciences
Start Date of Conference03/01/2018
End Date of Conference06/01/2018
Place of ConferenceHawaii
Country/Region of ConferenceUnited States of America
Proceedings TitleProceedings of the 51st Hawaii International Conference on System Sciences
Year2018
Pages2804 - 2813
ISBN978-0-9981331-1-9
LanguagesEnglish-United States

Last updated on 2020-26-05 at 00:47