Associations between shift work and glycemic control in Hong Kong Chinese patients with type 2 diabetes
Refereed conference paper presented and published in conference proceedings


摘要Considerable data exist on how shift work increases insulin resistance, the risk of metabolic syndrome and incidence of type 2 diabetes (T2D). However, few research has studied the influence of shift work on glycemic control in diabetes population. We aimed to examine whether shift work is associated with glycemic control in Hong Kong Chinese patients with T2D.

This was a cross-sectional study including patients with T2D recruited from the Hong Kong Diabetes Registry [1] between July 2010 and June 2015. The information of working patterns was collected by self-reported questionnaire. Indices of glycemic control including fasting plasma glucose (FPG) and glycated hemoglobin (HbA1c) were measured. Sleep parameters were assessed by validated questionnaires including Epworth Sleepiness Scale (ESS) and Insomnia Severity Index (ISI). Excessive daytime sleepiness (EDS) was defined as ESS score ≥ 10. Insomnia was defined as ISI >14. HbA1c < 7.0% was considered as reaching glycemic goal. Workers doing shift work frequently were defined as shift workers.

After excluded duplicate cases and cases with incomplete data, 4067 eligible patients were included in this present analysis. Mean age was 53.8±8.8 (standard deviation, SD) years and 58.1% were men. Median disease duration of diabetes was 7.0 (3.0-13.0) (inter-quartile range, IQR) years. In this cohort, 4.5% participants needed to take shift work frequently. T2D patients who were shift workers were younger (49.9±9.8 years versus 54.0±8.7 years, P<0.001) compared with others. They had higher FPG (8.1±2.8 mmol/l versus 7.6±2.5 mmol/l, P=0.012) and higher HbA1c (7.8±1.7% versus 7.5±1.5%, P=0.015). After adjustment for age, gender, BMI, disease duration of diabetes, anxiety/depression status, EDS and insomnia, shift work was associated with higher FPG and HbA1c (β=0.43, P=0.031 and β=0.23, P=0.046 respectively). A lower percentage of shift workers with T2D reached glycemic goal compared to their non-shift work counterparts although not statistically significant (39.5% versus 43.6%, P = 0.301).

T2D patients who were shift workers had worse glycemic control compared to those non-shift workers.

This work was supported by Research Grants Council (RGC) of the Hong Kong SAR (Project no. CUHK 466711).

1. Kong AP, et al. Diabetes Care. 2014.
著者Chenzhao Ding, Jihui Zhang, Eric Siu Him Lau, Andrea On Yan Luk, Wing Yee So, Ronald Ching Wan Ma, Kai Chow Choi, Juliana Chung Ngor Chan, Yun Kwok Wing, Alice Pik Shan Kong
會議名稱1st Interdisciplinary Behavioral Health Conference: Opportunities and Challenges
會議論文集題名1st Interdisciplinary Behavioral Health Conference: Opportunities and Challenges
關鍵詞type 2 diabetes, shift work, glycemic control, Chinese

上次更新時間 2018-08-06 於 16:21