Childhood adversities and post-traumatic stress disorder: Evidence for stress sensitisation in the World Mental Health Surveys
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AbstractBackground:
Although childhood adversities are known to predict increased risk of post-traumatic stress disorder (PTSD) after traumatic experiences, it is unclear whether this association varies by childhood adversity or traumatic experience types or by age.

Aims:
To examine variation in associations of childhood adversities with PTSD according to childhood adversity types, traumatic experience types and life-course stage.

Method:
Epidemiological data were analysed from the World Mental Health Surveys (n = 27017).

Results:
Four childhood adversities (physical and sexual abuse, neglect, parent psychopathology) were associated with similarly increased odds of PTSD following traumatic experiences (odds ratio (OR)=1.8), whereas the other eight childhood adversities assessed did not predict PTSD. Childhood adversity–PTSD associations did not vary across traumatic experience types, but were stronger in childhood-adolescence and early-middle adulthood than later adulthood.

Conclusion:
Childhood adversities are differentially associated with PTSD, with the strongest associations in childhood-adolescence and early-middle adulthood. Consistency of associations across traumatic experience types suggests that childhood adversities are associated with generalised vulnerability to PTSD following traumatic experiences.
Acceptance Date01/07/2017
All Author(s) ListMcLaughlin KA, Koenen KC, Bromet EJ, Karam EG, Liu H, Petukhova M, Ruscio AM, Sampson NA, Stein DJ, Aguilar-Gaxiola S, Alonso J, Borges G, Demyttenaere K, Dinolova RV, Ferry F, Florescu S, de Girolamo G, Gureje O, Kawakami N, Lee S, Navarro-Mateu F, Piazza M, Pennell BE, Posada-Villa J, Ten Have M, Viana MC, Kessler RC
Journal nameThe British Journal of Psychiatry
Year2017
Month11
Volume Number211
Issue Number5
Pages280 - 288
ISSN0007-1250
LanguagesEnglish-United Kingdom

Last updated on 2020-30-09 at 00:39