Worldwide Occurrence and Investigations of Contamination of Herbal Medicines by Tropane Alkaloids
Publication in refereed journal

香港中文大學研究人員
替代計量分析
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其它資訊
摘要Tropane alkaloids occur mainly in Solanaceae plants. In the present review, the main objective is to describe the worldwide occurrence and investigations of anticholinergic poisoning due to the contamination of herbal teas and herbs by tropane alkaloids. Tropane alkaloid poisoning can occur after consumption of any medicinal plant if Solanaceae plants or plant parts are present as contaminants. Globally, almost all reports in 1978–2014 involve herbal teas and one of the prescribed herbs in composite formulae. Contamination most likely occurs during harvest or processing. As for prescribed herbs, on-site inspection is necessary to exclude cross-contamination and accidental mix-up at the retail level. The diagnosis is confirmed by screening for the presence of Solanaceae species and tropane alkaloids. Herbal teas and herbs contaminated by tropane alkaloids can pose a serious health hazard because these relatively heat-stable alkaloids may exist in large quantities. The WHO repeatedly emphasises the importance of good agricultural and collection practices for medicinal plants. DNA barcoding is increasingly used to exclude the presence of contaminants (particularly toxic species) and product substitution. All suspected cases should be reported to health authorities so that investigations along the supply chain and early intervention measures to protect the public can be initiated.
出版社接受日期15.09.2017
著者Thomas Y. K. Chan
期刊名稱Toxins
出版年份2017
月份9
卷號9
期次9
頁次284
國際標準期刊號2072-6651
語言英式英語
關鍵詞Tropane alkaloids, anticholinergic poisoning, herbal medicines

上次更新時間 2020-18-10 於 02:32