A Randomized Controlled Trial of the Impact of MusicTherapy on Pain and Stress Reduction During Transvaginal Ultrasound-guided Oocyte Retrieval
Refereed conference paper presented and published in conference proceedings


摘要Study question: Does music therapy reduce pain and stress scores during transvaginal ultrasound-guided oocyte retrieval (TUGOR)?
Summary answer: Both group of women had similar stress score but women in the music group experienced significantly less pain score.
What is known already: A recent randomized controlled trial demonstrated that music therapy reduced anxiety in patients undergoing embryo transfer. However, it is not known if music therapy may help in women undergoing
Study design, size, duration: A randomized controlled open label study of 180 women (music group n = 60, headphone only group n = 60, no intervention group, n = 60) undergoing TUGOR over a 12 months period in an IVF unitof a university based teaching hospital.
Participants/materials, setting, methods: Women undergoing TUGOR were recruited and randomized into 3 groups (music group, headphone only group and no intervention group). Patient’s psychological status was systematically
assessed through various instruments including visual analog scale of pain (VAS-P), state-trait anxiety inventories (STAI), Beck depression inventory (BDI) and general health questionnaire (GHQ). Salivary alpha amylase (sAA) was
examined before and after TUGOR.
Main results and the role of chance: There was no difference in mean (±SD) psychological scores between 3 groups in (STAI, music group: 54.8 ± 9.4, headphone only group: 56.9 ± 10.3, no intervention group: 54.9 ± 10.2; BDI,
music group: 6.6 ± 6.2, headphone only group: 6.8 ± 6.4, no interventiongroup: 8.1 ± 8.2; GHQ, music group: 2.3 ± 2.5, headphone only group: 2.8 ± 2.8, no intervention group: 2.5 ± 2.6). There was also no difference in the change of mean (± SD) sAA level (U/ml) between 3 groups (music group: 4.5 ± 0.7, headphone only group: 4.7 ± 0.6, no intervention group: 4.6 ± 0.7). However, the mean (± SD) vaginal pain scores in women receiving music therapy
(19.3 ± 22.4) was significantly (P< 0.034) lower than those receiving headphone only (29.4 ± 26.9) and no intervention (30.6 ± 28.2). Limitations, reasons for caution: Due to the nature of the study, double
blinding was not possible.
Wider implications of the findings: This is the first randomized controlled trial to demonstrate that music therapy significantly reduced the perception of pain during TUGOR. Music therapy, being simple and inexpensive, is now routinely offered in our unit during TUGOR.
Trial registration number: This study was registered at Centre for Clinical Research And Biostatistics (Primary Registry and Trial Identifying Number: ChiCTR-TRC-11001657).
著者Cheung CWC, Kong GWS, Wong AWY, Saravelos SH, Cheung LP, Li TC
會議名稱The 33rd Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE)
會議論文集題名Human Reproduction
期次Supp 1
出版社Oxford University Press

上次更新時間 2018-20-01 於 18:37