Incidence of inflammatory bowel disease in Asia-Pacific: First results from the Asia-Pacific epidemiology Crohn's and colitis (ACCESS) study
Refereed conference paper presented and published in conference proceedings

香港中文大學研究人員

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摘要Background: Incidence of inflammatory bowel disease (IBD) is increasing in Asia but there are no comparative epidemiological data. The ACCESS study assessed the incidence of IBD across 21 centers, 12 districts and 7 countries in Asia-Pacific. Methods: A prospective, populationbased IBD inception study was conducted (1.4.2011-31.3.2012) using web-based database. Results: 380 new cases were identified: 212 (55.8%) ulcerative colitis (UC), 149 (39.2%) Crohn's disease (CD), and 19 (5.0%) indeterminate colitis (IC). Mean age at diagnosis 40 years (SD 16.4). Crude annual overall incidence per 100,000 of IBD was 1.02 (95% CI 0.91-1.14) (UC 0.63, CD 0.35 and IC 0.04) in Asia and 23.67 (95% CI 18.48-29.85) (UC 7.33, CD 14.00, IC 2.33) in Australia (Table 1). Ratio of CD to UC was 2.0, 0.8, and 0.4 in Australia, Hong Kong, and rest of Asia, respectively. Median number of months from symptom to diagnosis was 6 months (IQR 3-24) for Australia and 4.9 months (IQR 1.4-16.3) for Asia. Disease site was similar in Asia and Australia. Complicated CD (B2+B3) was more common in Asia than Australia (34% vs. 12%). Conclusion: This is the first prospective, population-based incidence study of IBD across Asia- Pacific. Incidence of IBD in Asia showed geographical variation. IBD can be as severe, or more severe in Asia than the West. (Table Presented).
著者Ng SC, Ching J, Wong M, Tang W, Kamm M, Bell S, Studd C, Hui AJ, Wong TC, Leung V, Tsang S, Leong R, Mustaffa N, Kasturiratne A, Mufeena MNF, De Silva HJ, Ho Yu H, Li MF, Ng KK, Ling KL, Ooi CJ, Ong D, Goh KL, Hilmi I, Wang YF, Ouyang Q, Zeng Z, Chen MH, Wang X, Wu KC, Simadibrata M, Abdullah M, Pisespongsa P, Rerknimitr R, Aniwan S, Manatsathit S, Chan FKL
會議名稱Asian Pacific Digestive Week
會議開始日05.12.2012
會議完結日08.12.2012
會議地點Bangkok
會議國家/地區泰國
會議論文集題名JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
出版年份2012
月份12
卷號27
期次Suppl. 5
頁次12 - 13
國際標準期刊號0815-9319
電子國際標準期刊號1440-1746
語言美式英語

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