Incidence of inflammatory bowel disease in Asia-Pacific: First results from the Asia-Pacific epidemiology Crohn's and colitis (ACCESS) study
Refereed conference paper presented and published in conference proceedings


Full Text

Times Cited
Web of Science0WOS source URL (as at 28/11/2021) Click here for the latest count

Other information
AbstractBackground: Incidence of inflammatory bowel disease (IBD) is increasing in Asia but there are no comparative epidemiological data. The ACCESS study assessed the incidence of IBD across 21 centers, 12 districts and 7 countries in Asia-Pacific. Methods: A prospective, populationbased IBD inception study was conducted (1.4.2011-31.3.2012) using web-based database. Results: 380 new cases were identified: 212 (55.8%) ulcerative colitis (UC), 149 (39.2%) Crohn's disease (CD), and 19 (5.0%) indeterminate colitis (IC). Mean age at diagnosis 40 years (SD 16.4). Crude annual overall incidence per 100,000 of IBD was 1.02 (95% CI 0.91-1.14) (UC 0.63, CD 0.35 and IC 0.04) in Asia and 23.67 (95% CI 18.48-29.85) (UC 7.33, CD 14.00, IC 2.33) in Australia (Table 1). Ratio of CD to UC was 2.0, 0.8, and 0.4 in Australia, Hong Kong, and rest of Asia, respectively. Median number of months from symptom to diagnosis was 6 months (IQR 3-24) for Australia and 4.9 months (IQR 1.4-16.3) for Asia. Disease site was similar in Asia and Australia. Complicated CD (B2+B3) was more common in Asia than Australia (34% vs. 12%). Conclusion: This is the first prospective, population-based incidence study of IBD across Asia- Pacific. Incidence of IBD in Asia showed geographical variation. IBD can be as severe, or more severe in Asia than the West. (Table Presented).
All Author(s) ListNg SC, Ching J, Wong M, Tang W, Kamm M, Bell S, Studd C, Hui AJ, Wong TC, Leung V, Tsang S, Leong R, Mustaffa N, Kasturiratne A, Mufeena MNF, De Silva HJ, Ho Yu H, Li MF, Ng KK, Ling KL, Ooi CJ, Ong D, Goh KL, Hilmi I, Wang YF, Ouyang Q, Zeng Z, Chen MH, Wang X, Wu KC, Simadibrata M, Abdullah M, Pisespongsa P, Rerknimitr R, Aniwan S, Manatsathit S, Chan FKL
Name of ConferenceAsian Pacific Digestive Week
Start Date of Conference05/12/2012
End Date of Conference08/12/2012
Place of ConferenceBangkok
Country/Region of ConferenceThailand
Proceedings TitleJOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
Year2012
Month12
Volume Number27
Issue NumberSuppl. 5
Pages12 - 13
ISSN0815-9319
eISSN1440-1746
LanguagesEnglish-United States

Last updated on 2021-29-11 at 00:39