Multi-target Pharmacological Effects of Platycodin D
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摘要Plant secondary metabolites are considered as a valuable source to identify promising lead compounds for developing novel drugs. Platycodin D is regarded as one of the major bioactive compounds from medicinal plant Platycodon grandiflorum, which attracts growing interests from researchers these years due to its potent effects. The present paper reviews the latest knowledge of biological and pharmacological activities of platycodin D. In vitro and in vivo experimental evidences have revealed that platycodin D demonstrates multiple pharmacological properties including anti-oxidative, anti-inflammatory, anticancer, anti-obesity, anti-diabetes and hepatoprotective effects. The underlying mechanisms of multiple therapeutic functions of platycodin D are very likely associated with its antiinflammatory and antioxidant nature whereas low bioavailability should be considered in drug development.
著者Zhong-Rong Zhang, Chun Wai Chan
期刊名稱Mini-Reviews in Organic Chemistry
出版年份2017
卷號14
期次6
出版社Bentham Science Publishers
國際標準期刊號1570-193X
電子國際標準期刊號1875-6298
語言英式英語
關鍵詞Platycodin D, Platycodon grandiflorum, Antioxidant, Anti-inflammation, Anticancer, anti-obesity, anti-diabetes, hepatoprotection

上次更新時間 2021-20-10 於 00:53