Identifying the risk of sarcopenia in patients with knee Osteoarthritis
Refereed conference paper presented and published in conference proceedings
香港中文大學研究人員
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摘要Introduction: As patients with osteoarthritis (OA) often have concomitant sarcopenia, these conditions have been recognised as important health issues affecting the aging population. This study aimed to identify the predictors of sarcopenia in patients with OA, and to document the impact on physical function and quality of life.
Methods: In this cross-sectional study, 100 patients with knee OA were recruited. Quality of life, appendicular muscle mass index (ASM), handgrip strength, and gait speed were assessed. Logistic regression models were used to identify risk factors of sarcopenia in knee OA patients.
Results: ASM (OR=0.028; 95% CI=0.003, 0.254) and handgrip strength (OR=0.441; 95% CI=0.003, 0.254) were the independent predictors of sarcopenia. Among the patients with knee OA, those with end stage tended to be older, having longer history of knee OA and have slower gait speed (p=0.038) than those with early stage knee OA, which consequently correlated with poorer self-report physical (p=0.028) and social functioning (p=0.046).
Discussion and Conclusion: Handgrip strength instead of gait speed shows more reliability in screening sarcopenia in knee OA patients. Further research could explore the effects of improving muscle strength for knee OA patients and prevention of sarcopenia.
Methods: In this cross-sectional study, 100 patients with knee OA were recruited. Quality of life, appendicular muscle mass index (ASM), handgrip strength, and gait speed were assessed. Logistic regression models were used to identify risk factors of sarcopenia in knee OA patients.
Results: ASM (OR=0.028; 95% CI=0.003, 0.254) and handgrip strength (OR=0.441; 95% CI=0.003, 0.254) were the independent predictors of sarcopenia. Among the patients with knee OA, those with end stage tended to be older, having longer history of knee OA and have slower gait speed (p=0.038) than those with early stage knee OA, which consequently correlated with poorer self-report physical (p=0.028) and social functioning (p=0.046).
Discussion and Conclusion: Handgrip strength instead of gait speed shows more reliability in screening sarcopenia in knee OA patients. Further research could explore the effects of improving muscle strength for knee OA patients and prevention of sarcopenia.
著者Qian-wen Wang, Gene Chi-Wai Man, Chi-Yin Choi, Ming-Qian Yu, Xin He, Jonathan Patrick Ng, Michael Tim-Yun Ong, Patrick Shu-Hang Yung
會議名稱The HKOA 43rd Annual Congress of The Hong Kong Orthopaedic Association
會議開始日04.11.2023
會議完結日05.11.2023
會議地點Hong Kong
會議國家/地區香港
出版年份2023
月份11
出版社Hong Kong Academy of Medicine Press
出版地Hong Kong
頁次109 - 109
語言美式英語
