Identifying the risk of sarcopenia in patients with knee Osteoarthritis
Refereed conference paper presented and published in conference proceedings
CUHK Authors
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AbstractIntroduction: As patients with osteoarthritis (OA) often have concomitant sarcopenia, these conditions have been recognised as important health issues affecting the aging population. This study aimed to identify the predictors of sarcopenia in patients with OA, and to document the impact on physical function and quality of life.
Methods: In this cross-sectional study, 100 patients with knee OA were recruited. Quality of life, appendicular muscle mass index (ASM), handgrip strength, and gait speed were assessed. Logistic regression models were used to identify risk factors of sarcopenia in knee OA patients.
Results: ASM (OR=0.028; 95% CI=0.003, 0.254) and handgrip strength (OR=0.441; 95% CI=0.003, 0.254) were the independent predictors of sarcopenia. Among the patients with knee OA, those with end stage tended to be older, having longer history of knee OA and have slower gait speed (p=0.038) than those with early stage knee OA, which consequently correlated with poorer self-report physical (p=0.028) and social functioning (p=0.046).
Discussion and Conclusion: Handgrip strength instead of gait speed shows more reliability in screening sarcopenia in knee OA patients. Further research could explore the effects of improving muscle strength for knee OA patients and prevention of sarcopenia.
Methods: In this cross-sectional study, 100 patients with knee OA were recruited. Quality of life, appendicular muscle mass index (ASM), handgrip strength, and gait speed were assessed. Logistic regression models were used to identify risk factors of sarcopenia in knee OA patients.
Results: ASM (OR=0.028; 95% CI=0.003, 0.254) and handgrip strength (OR=0.441; 95% CI=0.003, 0.254) were the independent predictors of sarcopenia. Among the patients with knee OA, those with end stage tended to be older, having longer history of knee OA and have slower gait speed (p=0.038) than those with early stage knee OA, which consequently correlated with poorer self-report physical (p=0.028) and social functioning (p=0.046).
Discussion and Conclusion: Handgrip strength instead of gait speed shows more reliability in screening sarcopenia in knee OA patients. Further research could explore the effects of improving muscle strength for knee OA patients and prevention of sarcopenia.
All Author(s) ListQian-wen Wang, Gene Chi-Wai Man, Chi-Yin Choi, Ming-Qian Yu, Xin He, Jonathan Patrick Ng, Michael Tim-Yun Ong, Patrick Shu-Hang Yung
Name of ConferenceThe HKOA 43rd Annual Congress of The Hong Kong Orthopaedic Association
Start Date of Conference04/11/2023
End Date of Conference05/11/2023
Place of ConferenceHong Kong
Country/Region of ConferenceHong Kong
Year2023
Month11
PublisherHong Kong Academy of Medicine Press
Place of PublicationHong Kong
Pages109 - 109
LanguagesEnglish-United States
