Crosstalk between gut microbiota and RNA N6-methyladenosine modification in cancer
Publication in refereed journal

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其它資訊
摘要The gut microbiota plays a crucial role in regulating various host metabolic, immune, and neuroendocrine functions, and has a significant impact on human health. Several lines of evidence suggest that gut dysbiosis is associated with a variety of diseases, including cancer. The gut microbiota can impact the development and progression of cancer through a range of mechanisms, such as regulating cell proliferation and death, modulating the host immune response, and altering the host metabolic state. Gene regulatory programs are considered critical mediators between the gut microbiota and host phenotype, of which RNA N6-methyladenosine (m6A) modifications have attracted much attention recently. Aberrant m6A modifications have been shown to play a crucial role in cancer development. This review aims to provide an overview of the diverse roles of gut microbiota and RNA m6A modifications in cancer and highlight their potential interactions in cancer development.
著者Su H., Cheung H., Lau H.C.H., Chen H., Zhang X., Qin N., Wang Y., Chan M.T.V., Wu W.K.K., Chen H.
期刊名稱FEMS Microbiology Reviews
出版年份2023
月份7
卷號47
期次4
出版社Oxford University Press
文章號碼fuad036
國際標準期刊號0168-6445
電子國際標準期刊號1574-6976
語言英式英語
關鍵詞cancer, crosstalk, microbiota, N6-methyladenosine

上次更新時間 2024-16-10 於 14:12