Effect of sarcopenia in elderly women with vertebral compression fracture on global sagittal alignment and its relationship with quality of life
Refereed conference paper presented and published in conference proceedings
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摘要Introduction: Vertebral compression fracture (VCF) is the most common type of osteoporotic fracture, while Sarcopenia is characterised by the degenerative loss of muscle mass and quality. In this study, we wish to investigate whether VCF patients with sarcopenia have more severe global sagittal alignment (GSA) imbalance, and whether such changes are associated with quality of life, disability, and pain.
Methods: Chinese female patients with VCF aged >60 years were recruited to this study, then classified into sarcopenic or non-sarcopenic groups. Whole-body standing radiographs were acquired for evaluating GSA from spine to lower limb. Parameters include thoracic kyphosis (TK), lumbar lordosis (LL), pelvic incidence (PI), pelvic tilt (PT), sagittal vertical axis (SVA), T1 pelvic angle (TPA), knee flexion angle (KA) and, ankle dorsiflexion angle (AA). Quality of life was assessed with the Oswestry Disability Index (ODI), Short-form (SF)-12 and The Numerical Pain Rating Scale (NPRS).
Results: In total, 36 sarcopenic and 26 non-sarcopenic VCF patients were recruited. There was a significant difference in KA (p=0.046) between sarcopenic and non-sarcopenic VCF patients. An increase in KA also showed a positive correlation with more severe back pain (r=0.22). In VCF patients with sarcopenia, LL was found to be negatively correlated with ODI scores.
Discussion and Conclusion: Current findings may imply the worsening of sagittal imbalance and increase in pain may be due to the increase of muscle frailty. The identification on these GSA changes may be a potential prognostic indicator for conservative management in improving the disability for VCF patients with sarcopenia.
Methods: Chinese female patients with VCF aged >60 years were recruited to this study, then classified into sarcopenic or non-sarcopenic groups. Whole-body standing radiographs were acquired for evaluating GSA from spine to lower limb. Parameters include thoracic kyphosis (TK), lumbar lordosis (LL), pelvic incidence (PI), pelvic tilt (PT), sagittal vertical axis (SVA), T1 pelvic angle (TPA), knee flexion angle (KA) and, ankle dorsiflexion angle (AA). Quality of life was assessed with the Oswestry Disability Index (ODI), Short-form (SF)-12 and The Numerical Pain Rating Scale (NPRS).
Results: In total, 36 sarcopenic and 26 non-sarcopenic VCF patients were recruited. There was a significant difference in KA (p=0.046) between sarcopenic and non-sarcopenic VCF patients. An increase in KA also showed a positive correlation with more severe back pain (r=0.22). In VCF patients with sarcopenia, LL was found to be negatively correlated with ODI scores.
Discussion and Conclusion: Current findings may imply the worsening of sagittal imbalance and increase in pain may be due to the increase of muscle frailty. The identification on these GSA changes may be a potential prognostic indicator for conservative management in improving the disability for VCF patients with sarcopenia.
出版社接受日期05.11.2022
著者Cheuk-Kin Kwan, Koko Shaau-Yiu Ko,Leo Tsz-Ching Chau,Zongshan Hu,Ying-Yang Law,Winnie Chiu-Wing Chu,Gene Chi-Wai Man,Sheung-Wai Law
會議名稱The Hong Kong Orthopaedic Association 42nd Annual Congress 2022
會議開始日05.11.2022
會議完結日06.11.2022
會議地點Hong Kong
會議國家/地區香港
會議論文集題名The Hong Kong Orthopaedic Association 42nd Annual Congress 2022
出版年份2022
月份11
出版社HKAM Press
出版地Hong Kong
語言英式英語
