A Safety and Feasibility Trial of Ultrasound-Guided Radiofrequency Ablation of Parotid Warthin's Tumor
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AbstractObjective: To determine if ultrasound-guided (USG) radiofrequency ablation (RFA) of Parotid Warthin's tumor under local anesthesia is a safe and effective procedure.

Study design: Safety and feasibility study.

Setting: Tertiary academic medical center.

Methods: This is an IDEAL phase 2a trial in a tertiary referral center. Twenty patients with Parotid Warthin's tumor were recruited. RFA was done between September and December 2021 for all 20 patients using a CoATherm AK-F200 machine with a disposable, 18G × 7 mm radiofrequency electrode. Results and follow-up statistics were compared with a historic sample of patients with parotid Warthin's tumor who underwent parotidectomy between 2019 and 2021 in the same center.

Results: Nineteen patients were included in the analysis as 1 patient dropped out after 4 weeks of follow-up. The mean age for the RFA group was 67 years old with most of them being male smokers. At a median of 45 weeks (44-47 weeks) postprocedure there was a 7.48 mL (68.4%) volume reduction compared to baseline. Three patients had transient facial nerve (FN) paresis, 1 recovered within hours, and the other 2 by 12 weeks follow-up. Three patients had great auricular nerve numbness; 1 patient had infected hematoma treated in an out-patient manner. Compared to a historic cohort of parotidectomy patients for Warthin's tumor, there was no significant difference in FN paresis and other minor complications between the 2 treatment modalities.

Conclusion: The current analysis suggests that USG RFA of Warthin's Tumor is a safe alternative to parotidectomy with shorter operative time and length of stay.
Acceptance Date12/07/2023
All Author(s) ListDavid C M Yeung, Hanson H S Leung, Ronald Lai, Alex K F Lee, Jefferey K T Wong, Eddy W Y Wong, Jason Y K Chan, Eric H L Lau
Journal nameOtolaryngology - Head and Neck Surgery
Volume Number170
Issue Number1
Pages103 - 111
LanguagesEnglish-United Kingdom
Keywordslocal anesthesia, minimally invasive, parotid Warthin's tumor, radiofrequency ablation, safety and feasibility, ultrasound

Last updated on 2023-28-12 at 12:33