Epidemic and Emerging Coronaviruses (Severe Acute Respiratory Syndrome and Middle East Respiratory Syndrome)
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AbstractBats are the natural reservoirs of severe acute respiratory syndrome (SARS)-like coronaviruses (CoVs) and likely the reservoir of Middle East respiratory syndrome (MERS)-CoV. The clinical features of SARS-CoV infection and MERS-CoV infection are similar but MERS-CoV infection progresses to respiratory failure more rapidly. Although the estimated pandemic potential of MERS-CoV is lower than that of SARS-CoV, the case fatality rate of MERS is higher. The transmission route and the possibility of other intermediary animal sources remain uncertain among many sporadic primary cases. Clinical trial options for MERS-CoV infection include monotherapy and combination therapy.
All Author(s) ListHui DS
Journal nameClinics in Chest Medicine
Year2017
Month3
Volume Number38
Issue Number1
PublisherW B SAUNDERS CO-ELSEVIER INC
Pages71 - 86
ISSN0272-5231
eISSN1557-8216
LanguagesEnglish-United Kingdom
KeywordsSARS-CoV, MERS-CoV, Respiratory tract infections, Clinical features, Pathogenesis, Treatment
Web of Science Subject CategoriesRespiratory System;Respiratory System

Last updated on 2020-11-08 at 02:53