Thermal gradient induced tweezers for the manipulation of particles and cells
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AbstractOptical tweezers are a well-established tool for manipulating small objects. However, their integration with microfluidic devices often requires an objective lens. More importantly, trapping of non- transparent or optically sensitive targets is particularly challenging for optical tweezers. Here, for the first time, we present a photon-free trapping technique based on electro-thermally induced forces.
We demonstrate that thermal-gradient-induced thermophoresis and thermal convection can lead to trapping of polystyrene spheres and live cells. While the subject of thermophoresis, particularly in the micro- and nano-scale, still remains to be fully explored, our experimental results have provided a reasonable explanation for the trapping effect. The so-called thermal tweezers, which can be readily fabricated by femtosecond laser writing, operate with low input power density and are highly versatile in terms of device configuration, thus rendering high potential for integration with microfluidic devices as well as lab-on-a-chip systems.
Acceptance Date06/10/2016
All Author(s) ListJiajie Chen, Hengji Cong, Fong-Chuen Loo, Zhiwen Kang, Minghui Tang, Haixi Zhang, Shu-Yuen Wu, Siu-Kai Kong, Ho-Pui Ho
Journal nameScientific Reports
Year2016
Month11
Day17
Volume Number6
PublisherNature Publishing Group
Article number35814
ISSN2045-2322
eISSN2045-2322
LanguagesEnglish-United States

Last updated on 2020-25-10 at 02:47