The Effect of platelet-rich plasma injections on people with Achilles tendinopathy: a systematic review and meta-analysis
Refereed conference paper presented and published in conference proceedings


摘要Introduction: Achilles tendinopathy is commonly occurring among various populations. Platelet-rich plasma (PRP) injection was suggested, but its effectiveness is controversial. This systematic review and meta-analysis reviews the current evidence of the effect of PRP injection on Achilles tendinopathy.
Methods: This review follows the PRISMA guidelines. CINAHL via EBSCOhost, Cochrane Library, and PubMed were searched for RCTs comparing PRP injection to another conservative treatment on VISA-A score or max AT thickness. Risk of bias assessment was done with RoB2. Meta-analysis was performed with Revman 5.3.
Results: Six studies including 422 participants suffering from chronic mid-portion Achilles tendinopathy were identified. Two, one and three of them were with low risk, some concerns and high risk of bias, respectively. There were no statistically significant differences between PRP injection and control at all time-points for VISA-A score (short-term: MD=2.28, 95% confidence interval [CI]=[-1.95, 6.51], p=0.29; Intermediate-term: MD=1.83, 95% CI=[-2.66, 6.32], p=0.42; Long-term: MD=3.46, 95% CI=[-8.62, 15.55], p=0.56) and max AT thickness (Short-term: MD=0.26, 95% CI=[-0.71, 1.24], p=0.60; Intermediate-term: MD=-0.84, 95% CI=[-2.12, 0.43], p=0.20; Long-term: MD=-0.28, 95% CI=[-1.19, 0.64], p=0.55)
Discussion and Conclusion: Despite trends of increasing PRP injections, no solid evidence exists. Future studies need to standardise and investigate the injection site and technique and quantify the type and dose of PRP to ascertain if PRP injections are an effective treatment for Achilles tendinopathy.
著者Clarence Tsz-kit Mak, Patrick Shu-Hang Yung, Samuel Ka-Kin Ling
會議名稱The Hong Kong Orthopaedic Association 42nd Annual Congress
會議地點Hong Kong

上次更新時間 2023-27-07 於 16:29