Fine structural observations on the human sperm nuclear matrix
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AbstractThe nucleus of the mammalian sperm is formed after a series of morphological and biochemical changes during spermatogenesis. The human sperm nucleus, after sequential extraction with detergents, nuclease and ammonium sulfate, consists of a fibroskeletal structure which maintains the original nuclear shape. The chromatin-depleted skeleton is formed by thick and thin fibers as well as electron-dense patches of different sizes. These highly branched matrix fibers had average diameters of 35 and 12 nm. Polarization of the fibroskeletal structure is apparent and can be used as a good model to study the function of nuclear matrix in nuclear compartmentation in germ cells.
All Author(s) ListChew E.C., Cheng-Chew S.B., Yam H.F., Yang L., Leung P.Y., Liew C.T., Ding M.X.
Journal nameIn Vivo
Volume Number9
Issue Number3
PublisherInternational Institute of Anticancer Research
Place of PublicationGreece
Pages195 - 198
LanguagesEnglish-United Kingdom
KeywordsHuman sperm, Nuclear matrix, Ultrastructure

Last updated on 2021-23-01 at 02:27