Trichosanthin - A protein with multiple pharmacological properties
Publication in refereed journal

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其它資訊
摘要Trichosanthin (TCS), a protein isolated from the root tuber of the Chinese medicinal herb Trichosanthes kirilowii Maxim., is used to induce abortion in China. It also possesses immunomodulatory, anti-tumor and anti-human immunodeficiency virus properties. TCS is a member of the family of ribosome-inactivating proteins and inactivates eukaryotic ribosomes via its N-glycosidase activity. The gene encoding TCS has been cloned and over-expressed and the crystal structure of this protein resolved to 1.73 Å. In this review, the various pharmacological properties of TCS are discussed and assessed.
著者Shaw P.-C., Chan W.-L., Yeung H.-W., Ng T.-B.
期刊名稱Life Sciences
出版年份1994
月份7
日期5
卷號55
期次4
出版社Elsevier BV
出版地Netherlands
頁次253 - 262
國際標準期刊號0024-3205
語言英式英語
關鍵詞Abortion, HIV, Immunomodulation, Placenta, Trichosanthin, Tumor suppression

上次更新時間 2020-12-10 於 00:33