Memory Impairment Following Electroconvulsive Therapy in Chinese Patients with Schizophrenia: Meta-Analysis of Randomized Controlled Trials
Publication in refereed journal
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香港中文大學研究人員
替代計量分析
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其它資訊
摘要PURPOSE

To evaluate memory impairment associated with electroconvulsive therapy (ECT)–antipsychotic (AP) combination in comparison to AP monotherapy in schizophrenia.

DESIGN AND METHODS

A systematic literature search of randomized controlled trial (RCTs) was performed.

FINDINGS

Eleven RCTs that compared ECT–AP combination (n = 508) with AP monotherapy (n = 510) were analyzed. ECT–AP combination was associated with greater impairment than AP monotherapy in (1) endpoint memory quotient (MQ) of the Wechsler Memory Scale (WMS)–Revised at the end of the ECT course; and (2) picture recall, counting, recognition, and associative learning of the WMS. However, no group difference was found in MQ at 1 and 2 weeks post-ECT.

PRACTICE IMPLICATIONS

The ECT–AP combination was associated with greater transient memory impairment compared to AP monotherapy.
著者Wei Zheng, Guo Tong, Gabor S. Ungvari, Chee H. Ng, Helen F.K. Chiu, Ying-Qiang Xiang, Xiao-Lan Cao, Zheng-Rong Liu, Li-Rong Meng, Gábor Gazdag, Yu-Tao Xiang
期刊名稱Perspectives in Psychiatric Care
出版年份2017
出版社Wiley
國際標準期刊號0031-5990
語言英式英語

上次更新時間 2020-14-08 於 01:30