Combined application of prophylactic corneal cross-linking and laser in-situ keratomileusis - a review of literature
Publication in refereed journal
Officially Accepted for Publication

Times Cited
Web of Science4WOS source URL (as at 16/01/2021) Click here for the latest count
Altmetrics Information

Other information
AbstractLaser in-situ keratomileusis (LASIK) is safe and effective laser refractive procedures in treating refractive errors. However, regression of treatment and iatrogenic keratectasia remain to be a major concern, especially in treating thin cornea with high ametropia. Collagen cross-linking (CXL) is an effective method in stopping keratoconus progression through increasing the biomechanical strength of the cornea. Adjuvant cross-linking to refractive procedures can theoretically help prevent regression and reduce the risk of keratectasia development by increasing the mechanical stability of cornea. During the procedure, riboflavin is directly applied to the corneal stroma, thereby reducing the need of de-epithelialization as in the conventional protocol for keratoconus. Currently, there is still no consensus regarding the indication of CXL during refractive procedure, nor any standardized treatment protocol. This article aims to summarize the current evidence regarding the use of adjuvant CXL in LASIK.
Acceptance Date26/09/2016
All Author(s) ListTommy C. Y. Chan, Alex L. K. Ng, Karen K. W. Chan, George P. M. Cheng, Ian Y. H. Wong, Vishal Jhanji
Journal nameActa Ophthalmologica
Volume Number95
Issue Number7
LanguagesEnglish-United Kingdom
Keywordscollagen cross-linking; laser in-situ keratomileusis; LASIK ; refractive surgery

Last updated on 2021-17-01 at 01:36