A randomized controlled neurophysiological study of a Chinese Chan -based mind-body intervention in patients with major depressive disorder
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摘要Our previous studies have reported the therapeutic effects of 10-session Chinese Chan-based Dejian mind-body interventions (DMBI) in reducing the intake of antidepressants, improving depressive symptoms, and enhancing the attentional abilities of patients with depression. This study aims to explore the possible neuroelectrophysiological mechanisms underlying the previously reported treatment effects of DMBI in comparison with those of cognitive behavioral therapy (CBT). Seventy-five age-, gender-, and education-matched participants with depression were randomly assigned to receive either CBT or DMBI or placed on a waitlist. Eyes-closed resting EEG data were obtained individually before and after 10 weeks. After intervention, the DMBI group demonstrated significantly enhanced frontal alpha asymmetry (an index of positive mood) and intra- and interhemispheric theta coherence in frontoposterior and posterior brain regions (an index of attention). In contrast, neither the CBT nor the waitlist group showed significant changes in EEG activity patterns. Furthermore, the asymmetry and coherence indices of the DMBI group were correlated with self-reported depression severity levels and performance on an attention test, respectively. The present findings provide support for the effects of a Chinese Chan-based mind-body intervention in fostering human brain states that can facilitate positive mood and an attentive mind. © 2013 Agnes S. Chan et al.
著者Chan A.S., Han Y.M.Y., Sze S.L., Wong Q.Y., Cheung M.-C.
期刊名稱Evidence-Based Complementary and Alternative Medicine
出版年份2013
月份1
日期1
卷號2013
出版社Oxford University Press
出版地United Kingdom
國際標準期刊號1741-427X
電子國際標準期刊號1741-4288
語言英式英語

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