In vitro antiviral activities of Chinese medicinal herbs against duck hepatitis B virus
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AbstractFifty-six different Chinese medicinal herbs from 29 families were evaluated for their antiviral activities against duck hepatitis B virus (DHBV) in vitro. The DHBV DNA level in primary duck hepatocyte cultures was monitored by dot blot hybridization and the cytotoxicity was evaluated by MTT assay. Anti-DHBV activities were found more strongly in the aqueous extracts of Ardisia chinensis and Pithecellobium clypearia with selective indices of 2.6 and >2.7, respectively, which were comparable to that of 2′,3′- dideoxycytidine. Further research on the isolation of the active antiviral phytochemicals from these herbs may provide alternative options for the treatment of chronic hepatitis B. Copyright © 2006 John Wiley & Sons, Ltd.
All Author(s) ListLeung K.T., Chiu L.C.M., Lam W.S., Li Y., Sun S.S.M., Ooi V.E.C.
Journal namePhytotherapy Research
Year2006
Month10
Day1
Volume Number20
Issue Number10
PublisherJohn Wiley & Sons Inc.
Place of PublicationUnited States
Pages911 - 914
ISSN0951-418X
eISSN1099-1573
LanguagesEnglish-United Kingdom
KeywordsAntiviral, Chinese medicinal herbs, Duck hepatitis B virus

Last updated on 2020-12-07 at 00:04