Can We Predict the Bone Quality and Bone Strength by Assessing Handgrip Muscle Strength in Normal Chinese Adolescents?
Other conference paper


The objective of this study was to evaluate the correlation between muscle strength and bone quality in adolescents after adjusted for maturity and body size. Methods Five hundred and fifty-one normal boys and girls
aged 7 to 17 years were randomly recruited from local primary and secondary school. Muscle strength of non-dominant hand was assessed by standard handgrip dynamometer. Bone quality of distal radius was assessed with High resolution peripheral quantitative computed tomography (HR-pQCT) and bone mechanical properties (stiffness, failure load and apparent modulus) were evaluated with finite element analysis (FEA). Partial correlation for adjustment for age, height and weight was used for statistical analysis. Results In girls, there was significant correlation between muscle strength and total, cortical and trabecular area of distal radius (R ranged from 0.13 to 0.33). In boys, in addition to cortical area and cortical thickness, muscle strength was also correlated positively with vBMD in both cortical and trabecular compartment, trabecular bone volume fraction (BV/TV) and trabecular thickness (R ranged from 0.17 to 0.33) and negatively correlated with SMI (R=-0.25). Positive correlation between stiffness, failure load and muscle strength was detected in both genders (R ranged from 0.23 to 0.42).

Our result indicated that bone morphometry parameters were well correlated with handgrip muscle strength in both genders. In boys, additional correlation with vBMD and trabecular micro-architectural parameters was found. Further studies are warranted to evaluate if handgrip muscle strength and other muscle parameters can predict bone density, bone quality and bone strength in different ages.
著者K. Y. Cheuk, V. W. Y. Hung, B. K. W. Ng, J. C. Y. Cheng,T. P. Lam
會議名稱8th International Conference on Osteoporosis and Bone Research
會議地點Chongqing, China

上次更新時間 2018-22-01 於 09:17