Chinese herbal medicines for atopic dermatitis: A systematic review
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AbstractAtopic dermatitis (AD) is a common chronic inflammatory skin disease in children that could adversely affect their quality of life, and its prevalence is increasing in the last few decades. As definitive cure is lacking, there has been a considerable interest on using traditional Chinese Herbal Medicines (CHM) as an alternative treatment for AD. However, no data are available to provide an overview of the use of CHM for AD. In this chapter, we explored all the available relevant literatures on the clinical applications of CHM for AD, including its indications, contraindications, individual medicines, formulae, regimes, effectiveness, efficacy, safety, adverse effects and toxicity. The main objective is to review the available clinical studies on CHM for its therapeutic use in AD patients and the potential adverse outcomes. Over 140 literatures were identified, including the observational designed studies (exploratory studies, descriptive studies and analytical studies as case series, cohort studies, case-control studies, cross-sectional studies), the experimental studies (quasi- and randomized controlled trials) and the qualitative studies. Based on the principles and workflows from Centre for Evidence-Based Medicine of Oxford University and Cochrane Review, only few studies were selected for the systematic review and further meta-analysis. The result showed that compared with modern medicine groups, combined use of CHMs and modern medicines was significantly effective as a treatment option for atopic dermatitis. However there was insufficient proof on its safety although no specific safety problem was reported in the clinical trials. More scientific evidences through comprehensive studies on the efficacy and safety of CHM for AD are still necessary for its wider application.
All Author(s) ListLi L., Hon K.L., Wang C.C., Leung P.C.
All Editor(s) Listed. by Brian L. Duke.
Detailed descriptioned. by Brian L. Duke.
Pages149 - 166
LanguagesEnglish-United Kingdom

Last updated on 2021-20-09 at 00:26