Effect of combined use of Fructus Schisandrae and statin on high-fat-diet-induced metabolic syndrome in rats
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Abstract1. The combined use of Fructus Schisandrae aqueous extract (FSE) and atorvastatin (AS) exerts no further synergistic effect on diet-induced non-alcoholic fatty liver disease in rats, compared with rats given AS alone.
2. The use of FSE can protect high-fat-fed rats from AS-induced liver toxicity.
3. Preliminary pharmacokinetic studies suggest that FSE can enhance plasma metabolites of AS but reduce the liver metabolites of AS.
All Author(s) ListWat E, Ng CF, Liu CL, Zhang C, Koon CM, Lau CP, Wong CW, Pang KY, Zhang X, Fung KP, Lau CBS, Leung PC
Journal nameHong Kong Medical Journal
Volume Number22
Issue Number6 Suppl 6
Pages24 - 27
LanguagesEnglish-United Kingdom

Last updated on 2021-23-09 at 00:24