Magnesium sulphate for aneurysmal subarachnoid hemorrhage: Why, how, and current controversy
Refereed conference paper presented and published in conference proceedings

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摘要The neuroprotective effect of magnesium sulphate infusion has been confirmed in experimental models. Pilot clinical trials using magnesium sulphate in patients with acute aneurysmal subarachnoid hemorrhage (SAH) have reported a trend toward a reduction in clinical deterioration due to delayed cerebral ischemia (DCI) and an improvement in clinical outcomes. However, our recent multicenter trials and systemic review failed to confirm benefit in neurological outcome. In post hoc analysis, data also did not support that a higher dose of magnesium sulphate infusion might improve clinical outcome. We here review the current literature, highlight these discrepancies, and explore alternatives. © 2013 Springer-Verlag Wien.
著者Wong G.K.C., Poon W.S.
出版年份2013
月份1
日期1
期次115
出版社Springer Verlag
出版地Germany
頁次45 - 48
國際標準書號9783709111918
國際標準期刊號0065-1419
語言英式英語
關鍵詞Clinical outcome, Delayed cerebral ischemia, Magnesium, Stroke, Subarachnoid hemorrhage

上次更新時間 2020-25-11 於 01:02